Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   SOR_RS00185 Genome accession   NC_015291
Coordinates   34967..36316 (+) Length   449 a.a.
NCBI ID   WP_000801584.1    Uniprot ID   F2QG98
Organism   Streptococcus oralis Uo5     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 29967..41316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS00160 (SOR_0034) plsX 30349..31341 (+) 993 WP_000717448.1 phosphate acyltransferase PlsX -
  SOR_RS00165 (SOR_0035) - 31347..31583 (+) 237 WP_000136434.1 acyl carrier protein -
  SOR_RS00170 (SOR_0036) - 31905..32081 (+) 177 WP_000180837.1 hypothetical protein -
  SOR_RS10280 (SOR_0037) - 32094..32285 (+) 192 WP_013670143.1 hypothetical protein -
  SOR_RS00175 (SOR_0038) - 32314..32484 (+) 171 WP_000933509.1 H354_08695 family bacteriocin-like peptide -
  SOR_RS00180 (SOR_0039) comA 32801..34954 (+) 2154 WP_000668323.1 peptide cleavage/export ABC transporter ComA Regulator
  SOR_RS00185 (SOR_0040) comB 34967..36316 (+) 1350 WP_000801584.1 competence pheromone export protein ComB Regulator
  SOR_RS00190 (SOR_0041) purC 36486..37193 (+) 708 WP_000043280.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  SOR_RS00195 (SOR_0042) - 37395..41120 (+) 3726 WP_001042268.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49917.93 Da        Isoelectric Point: 5.0423

>NTDB_id=40166 SOR_RS00185 WP_000801584.1 34967..36316(+) (comB) [Streptococcus oralis Uo5]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQLIVANYLEENKL
VKQGELLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYISQANGLRSNVSQQN
ANISSQNAAASQSQAEIGNLISQTEEKIRDYKTAKSAIEKGDQLDSQNPAYSFYQTYKNQGEEDPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGILDKGKITASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAATLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=40166 SOR_RS00185 WP_000801584.1 34967..36316(+) (comB) [Streptococcus oralis Uo5]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCGCTTCTGCTCGTGTTTCTGTTAGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTGTCTACCAGAGCGACTGTTG
AACCTAGTCGGATTATTGCTAATATCCAGTCGACTAGCAATCAACTCATCGTGGCCAATTATCTAGAAGAAAACAAACTA
GTCAAGCAGGGGGAACTCCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTTGAGGCATATGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCTAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGTTACCAGGAGATGTTTCGAGATTATATCAGCCAAGCGAATGGTCTAAGAAGTAATGTTTCTCAGCAAAAT
GCTAACATCTCCTCGCAGAATGCAGCAGCAAGTCAGAGTCAGGCTGAGATTGGCAATCTTATCAGCCAAACAGAGGAAAA
AATCCGAGACTACAAAACAGCTAAATCAGCGATTGAAAAAGGAGATCAACTGGATAGTCAGAATCCAGCCTACTCTTTTT
ACCAAACCTATAAAAACCAAGGTGAAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCGCAAGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGTTTAGCTACCTATCGTGTACAATATGCGGGTTCTGGAGCTCAACAAGCCTACGCAACGGGACTAGA
TAGTCAACTGGAATCACTCAAATCTCAGCACTTAGTTAAAGTCGGTCAGGAATTAACTCTTCTAGATCAGAAAATTTTGG
AGGCGGAATCAGGTAAGAAGGTTCAAGGAGGTATCCTAGATAAAGGTAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGAATCTACGATGGTTGCAGAAGGAACCTTGCTAGCCCAACTCTATCCATCCTTGGAAAAAGA
AGGAAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTCAAGATTGGGGACTCTGTCCGTTATACTA
CGACTAACGATGCCAAGAATCAAATTTTCCTGGATTCCACGATTACGAGTATTGATGCGACAGCTACAAAAACTGAAAAA
GGGAATTTCTTTAAAATTGAGGCGGAGACTAATTTAACTTCGGAACAGGCTGCAACACTTCGTTATGGTTTAGAAGGTCG
CCTGCAGATGATTACAGGAAAGAAAAGCTATCTCCGATATTTTTGGGATCAATTTTTAAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QG98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

84.152

99.777

0.84
  comB Streptococcus pneumoniae Rx1

82.812

99.777

0.826
  comB Streptococcus pneumoniae D39

82.812

99.777

0.826
  comB Streptococcus pneumoniae R6

82.812

99.777

0.826
  comB Streptococcus mitis NCTC 12261

82.589

99.777

0.824
  comB Streptococcus pneumoniae TIGR4

82.366

99.777

0.822
  comB Streptococcus gordonii str. Challis substr. CH1

55.31

100

0.557

Multiple sequence alignment