Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   SOR_RS00180 Genome accession   NC_015291
Coordinates   32801..34954 (+) Length   717 a.a.
NCBI ID   WP_000668323.1    Uniprot ID   F2QG97
Organism   Streptococcus oralis Uo5     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 27801..39954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS00150 (SOR_0032) - 28416..29585 (+) 1170 WP_000366403.1 pyridoxal phosphate-dependent aminotransferase -
  SOR_RS00155 (SOR_0033) recO 29582..30352 (+) 771 WP_000616126.1 DNA repair protein RecO -
  SOR_RS00160 (SOR_0034) plsX 30349..31341 (+) 993 WP_000717448.1 phosphate acyltransferase PlsX -
  SOR_RS00165 (SOR_0035) - 31347..31583 (+) 237 WP_000136434.1 acyl carrier protein -
  SOR_RS00170 (SOR_0036) - 31905..32081 (+) 177 WP_000180837.1 hypothetical protein -
  SOR_RS10280 (SOR_0037) - 32094..32285 (+) 192 WP_013670143.1 hypothetical protein -
  SOR_RS00175 (SOR_0038) - 32314..32484 (+) 171 WP_000933509.1 H354_08695 family bacteriocin-like peptide -
  SOR_RS00180 (SOR_0039) comA 32801..34954 (+) 2154 WP_000668323.1 peptide cleavage/export ABC transporter ComA Regulator
  SOR_RS00185 (SOR_0040) comB 34967..36316 (+) 1350 WP_000801584.1 competence pheromone export protein ComB Regulator
  SOR_RS00190 (SOR_0041) purC 36486..37193 (+) 708 WP_000043280.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80371.62 Da        Isoelectric Point: 6.8353

>NTDB_id=40165 SOR_RS00180 WP_000668323.1 32801..34954(+) (comA) [Streptococcus oralis Uo5]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKKHIHIADPDPGVKLTKISRERFAQEWTGVSLFMAPSPDYKPHKEKKQGLLSFLPI
LLKQRGLIINIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDNEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
KGDMTFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVILNQGKIVEEGTHADLLAQDGFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=40165 SOR_RS00180 WP_000668323.1 32801..34954(+) (comA) [Streptococcus oralis Uo5]
ATGAAATTTGGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTTGCTTCCTTGGCTATGGTCTTTGG
TTACTACGGTAGTTATTACTCCTTGGCTCACCTGCGAGAATTGGCCAAGACGACCATGGATGGGACGACTGCTTTGGGTC
TTGTAAAGGTGGCAGAGGAGATTGGTTTTGAAACGCGGGCTATCAAGGCGGATATGACGCTCTTTGACCTGCCAGATTTG
ACCTTTCCGTTTGTGGCTCATGTGCTCAAGGAAGGGAAATTGCTCCACTATTATGTGGTGACAGGTCAGGATAAAAAGCA
CATTCATATCGCTGATCCAGATCCAGGTGTTAAGCTGACCAAGATTTCCCGTGAGCGATTTGCGCAAGAATGGACAGGGG
TCAGTCTCTTTATGGCTCCGTCTCCAGACTATAAACCCCATAAGGAGAAAAAACAGGGGCTCCTATCCTTCTTGCCAATC
TTACTCAAACAGCGGGGCTTGATTATCAATATTGTTTTGGCAACACTCTTGGTGACCCTGATCAATATCGTGGGCTCTTA
TTATCTGCAGTCTATCATTGATAGTTACGTACCAGACCAGATGCGTTCGACATTGGGTATCATCTCAATAGGACTAGTCA
TCGTCTATATCCTCCAGCAGATCTTGTCCTATGCGCAGGAATACCTCTTGCTTGTTCTGGGGCAACGGTTGTCAATTGAC
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCGATGTCCTTTTTTGCGACACGTAGGACAGGAGAGATTGTCTC
TCGTTTTACGGATGCCAATAGTATCATTGACGCGCTAGCGTCGACCATTCTTTCAATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTTGTCCTGTTTTCACAAAATATGACACTCTTTTTCATTAGTCTGCTTGCGCTTCCCATCTATACAGTG
ATTATTTTTGCCTTTATGAAGCCTTTTGAAAAGATGAATCGGGACACTATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAACGGTATTGAGACCATTAAATCTTTGACCAGTGAAAGTTCACGCTATCAAAAGATTGACAATGAAT
TTGTAGCTTATCTGAAAAAATCTTTTACCTATAGTCGGGCAGAAAGTCAGCAAAAGGCTCTGAAAAAAGTCGCCCAGCTC
CTTCTCAATGTTGCCGTTCTCTGGATGGGAGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAATTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACCAAACTTCAAACAGCGCAGGTTG
CCAATAATCGTCTGAACGAGGTCTATCTGGTCGCTTCAGAGTTTGAGGAGAAGAAAACAGTTGAGGATTTGAGCATGATG
AAGGGAGATATGACCTTTAAGCAGGTTCACTATAAGTATGGCTATGGTCGTGACGTCTTGTCGGATATCAATTTGACCAT
TCCGCAAGGGTCTAAGATGGCTTTCGTGGGAATTTCAGGTTCGGGTAAGACGACCTTGGCCAAGATGATGGTTAATTTCT
ACGACCCTAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTTAATCAGATTGATAAAAAGGCCCTGCGCCAGTACATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGACATCTTACGAGCAGTTGAATTGGCAGAGATTCGGGAGGATATCGAGCGCATGCCACTGAATTATCAGACAG
AATTGACTTCGGATGGGGCAGGAATTTCAGGTGGACAACGTCAGCGAATCGCTCTGGCGCGTGCTCTCTTAACAGATGCA
CCTGTTCTGATATTGGATGAGGCGACCAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTGGATAATCTTATGGCTTT
AGACAAGACCTTGATTTTCATTGCCCACCGCTTGACCATCGCTGAGCGGACAGAAAAGGTTGTTATTTTGAATCAGGGCA
AGATTGTCGAAGAAGGCACCCATGCAGACTTGCTCGCACAGGATGGCTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(169-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QG97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

95.397

100

0.954
  comA Streptococcus pneumoniae Rx1

95.119

100

0.951
  comA Streptococcus pneumoniae D39

95.119

100

0.951
  comA Streptococcus pneumoniae R6

95.119

100

0.951
  comA Streptococcus mitis SK321

95.119

100

0.951
  comA Streptococcus pneumoniae TIGR4

94.7

100

0.947
  comA Streptococcus gordonii str. Challis substr. CH1

80.056

100

0.801
  comA/nlmT Streptococcus mutans UA159

64.296

100

0.643

Multiple sequence alignment