Detailed information NTG0040058

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SPNINV200_RS06185
• Genome accession: NC_017593
• Coordinates: 1186756..1187604 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705304.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae INV200
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1181756..1192604

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPNINV200_RS06165 (SPNINV200_11510)	metG	1182006..1183643 (-)	1638	WP_000021543.1	methionine--tRNA ligase	-
SPNINV200_RS06170 (SPNINV200_11520)	-	1183711..1184385 (-)	675	WP_000903082.1	CatA-like O-acetyltransferase	-
SPNINV200_RS12900	-	1184444..1184743 (-)	300	WP_001138382.1	hypothetical protein	-
SPNINV200_RS06180 (SPNINV200_11540)	-	1185231..1186184 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
SPNINV200_RS06185 (SPNINV200_11550)	dprA/cilB/dalA	1186756..1187604 (-)	849	WP_000705304.1	DNA-processing protein DprA	Machinery gene
SPNINV200_RS06190 (SPNINV200_11560)	-	1187700..1188389 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
SPNINV200_RS06195 (SPNINV200_11570)	-	1188401..1189276 (-)	876	WP_000837615.1	DMT family transporter	-
SPNINV200_RS06200 (SPNINV200_11580)	licA	1189266..1190135 (-)	870	WP_000411218.1	choline kinase LicA	-
SPNINV200_RS06205 (SPNINV200_11590)	-	1190152..1191174 (-)	1023	WP_000609886.1	ribitol-5-phosphate dehydrogenase	-
SPNINV200_RS06210 (SPNINV200_11600)	-	1191179..1191886 (-)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31076.75 Da
• Isoelectric Point: 5.4047

>NTDB_id=40058 SPNINV200_RS06185 WP_000705304.1 1186756..1187604(-) (dprA/cilB/dalA) [Streptococcus pneumoniae INV200]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=40058 SPNINV200_RS06185 WP_000705304.1 1186756..1187604(-) (dprA/cilB/dalA) [Streptococcus pneumoniae INV200]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGCTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	63.214	99.291	0.628
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.456	100	0.376