Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GJS33_RS02570 Genome accession   NZ_CP046041
Coordinates   529230..531383 (+) Length   717 a.a.
NCBI ID   WP_012515169.1    Uniprot ID   A0A2X3T8J4
Organism   Streptococcus equi subsp. zooepidemicus strain AZ-45470     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 524230..536383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS33_RS02540 (GJS33_02540) metG 524435..526438 (+) 2004 WP_154298741.1 methionine--tRNA ligase -
  GJS33_RS02545 (GJS33_02545) - 526996..527889 (+) 894 WP_012678373.1 helix-turn-helix domain-containing protein -
  GJS33_RS02550 (GJS33_02550) - 528242..528382 (+) 141 WP_012515166.1 hypothetical protein -
  GJS33_RS02555 (GJS33_02555) - 528495..528653 (+) 159 WP_021320463.1 hypothetical protein -
  GJS33_RS02560 (GJS33_02560) - 528667..528813 (+) 147 WP_021320464.1 hypothetical protein -
  GJS33_RS02565 (GJS33_02565) - 528836..529003 (+) 168 WP_012515168.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  GJS33_RS02570 (GJS33_02570) comA 529230..531383 (+) 2154 WP_012515169.1 peptide cleavage/export ABC transporter ComA Regulator
  GJS33_RS10005 comB 531398..531994 (+) 597 WP_269206546.1 hypothetical protein Regulator
  GJS33_RS10010 - 532004..532765 (+) 762 WP_282884772.1 HlyD family efflux transporter periplasmic adaptor subunit -
  GJS33_RS02580 (GJS33_02580) - 533274..533510 (+) 237 WP_024273149.1 hypothetical protein -
  GJS33_RS02585 (GJS33_02585) nrdF 533968..534981 (+) 1014 WP_043040212.1 class 1b ribonucleoside-diphosphate reductase subunit beta -
  GJS33_RS02590 (GJS33_02590) nrdI 534983..535390 (+) 408 WP_043025398.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80481.42 Da        Isoelectric Point: 9.0606

>NTDB_id=400514 GJS33_RS02570 WP_012515169.1 529230..531383(+) (comA) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MKFRRKHYRAQVDTRDCGVASLAMIYGYYGSYYSLATLREAAKTTQEGTTAFGLVKVSEALGFETRAIRADMSLFDVEGL
SYPFIAHVLKKGKFLHYYVVTGQDKKYIHIADPDPTVKLTCLSRQRFASEWTGVTIFIAPTPEYKPHKEKKNSLLDFVPL
LAKQKGLITNIVVATLLVTIINIIGSYYLQSIIDTYVPSVMKNTLGIISVGLVIVYALQQVISYAQEYLLLILGQRLSID
VILSYIKHIFNLPMSFFATRRTGEIVSRFNDANSIIDALASTILSIFLDVSVIVIISLVLFSQNVNLFVISLLALPIYAV
IIFAFMKPFERMNQETMEANSIMSSSIIEDINGIETIKSLTSEKIRYQKIDKEFVAYLKKSFNYSRAESQQRALKKVAQL
ILNVSILWIGANLVMDGKMSLGQLITYNSLLIYFTNPLENIINLQTKLQTAQVANNRLNEVYLVESEFSEKKNVQDLSLT
SGDIKFNDVSYRYGYGKDVLSEINLHIKRGSKVAFVGISGSGKTTLAKMIVSFFEPSKGEISLNNVNLNQIDKHALRQHI
NYLPQQPYVFNGTILENLLLGAREGTTQEDIMKAVELAEIKSDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDS
PVLILDEATSNLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEHVVVLDKGKIIEQGTHRDLVSQNGFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=400514 GJS33_RS02570 WP_012515169.1 529230..531383(+) (comA) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGAAATTTAGAAGAAAACACTACCGTGCTCAGGTTGATACTCGCGATTGTGGCGTAGCTTCTCTGGCCATGATTTACGG
TTATTATGGATCGTATTATTCGCTAGCAACGTTACGTGAAGCTGCAAAGACAACGCAGGAAGGGACTACAGCTTTTGGTT
TAGTCAAAGTTTCTGAGGCGCTTGGGTTTGAAACGAGAGCTATTAGGGCTGACATGAGTTTATTTGATGTGGAAGGATTA
TCTTATCCTTTTATTGCCCATGTTCTAAAAAAAGGTAAGTTCCTTCATTATTATGTGGTAACAGGACAAGATAAAAAATA
TATTCATATTGCAGATCCAGATCCAACTGTAAAGTTGACTTGTCTTTCTCGTCAGCGATTTGCTTCAGAGTGGACAGGTG
TGACAATTTTTATCGCTCCTACTCCTGAATACAAACCTCACAAGGAAAAGAAAAATAGTCTGCTAGATTTTGTGCCTCTC
CTAGCAAAGCAAAAAGGATTGATTACTAATATCGTTGTGGCAACGCTTTTGGTAACGATTATCAATATTATTGGTTCGTA
TTATCTTCAATCAATCATTGATACCTATGTTCCTAGTGTGATGAAGAATACACTAGGTATTATTTCCGTAGGTTTGGTTA
TTGTCTATGCCCTTCAACAAGTGATCTCATATGCGCAAGAGTATTTATTGCTGATATTAGGGCAACGTTTATCTATTGAT
GTAATTCTTTCTTATATCAAACATATTTTCAACCTTCCTATGTCTTTTTTCGCGACGAGAAGGACCGGGGAAATTGTTTC
TCGTTTTAATGATGCTAATTCAATCATTGATGCTTTAGCAAGTACAATTTTATCTATTTTCCTTGATGTTTCTGTCATTG
TAATTATATCTCTTGTTCTTTTTTCGCAGAATGTAAATCTATTTGTTATCAGTTTGCTTGCTCTGCCTATCTATGCAGTG
ATTATCTTTGCCTTCATGAAGCCATTTGAACGGATGAATCAAGAGACAATGGAAGCAAATTCAATCATGTCATCTTCTAT
TATTGAAGATATAAACGGTATTGAGACTATTAAATCATTAACTAGCGAAAAGATAAGATACCAAAAAATAGATAAAGAAT
TTGTAGCTTATCTTAAGAAATCTTTCAACTATAGTAGGGCAGAAAGCCAACAACGAGCATTGAAAAAAGTAGCTCAGCTT
ATCCTAAACGTGAGCATACTCTGGATAGGAGCCAATCTGGTTATGGACGGAAAAATGAGTTTAGGTCAACTGATTACCTA
TAACTCTCTCCTAATCTACTTTACAAATCCTCTGGAGAATATTATCAATCTTCAAACGAAACTTCAAACCGCTCAAGTCG
CTAATAATCGATTGAATGAGGTATATCTAGTTGAATCCGAGTTCTCTGAAAAGAAGAATGTTCAAGACTTATCTTTGACC
TCTGGTGACATAAAATTCAATGATGTTAGCTATCGATATGGATATGGAAAAGATGTTTTATCAGAAATAAATTTGCATAT
TAAACGAGGAAGCAAGGTTGCTTTTGTTGGGATTTCAGGTTCTGGAAAAACGACTTTAGCTAAGATGATTGTCAGTTTCT
TTGAACCAAGCAAAGGCGAAATATCATTAAATAATGTGAATCTAAATCAAATTGACAAACATGCTCTTCGCCAGCACATT
AACTATCTTCCTCAACAACCTTACGTATTTAATGGGACAATCCTTGAGAATTTACTTCTTGGAGCACGTGAAGGGACGAC
TCAAGAAGACATTATGAAGGCAGTAGAATTGGCTGAAATCAAGTCTGATATTGAACGTATGCCTTTGAATTATCAAACAG
AGTTAACCTCAGATGGTGCAGGGATTTCTGGAGGTCAACGTCAACGTATTGCCTTAGCAAGGGCATTATTGACAGATTCT
CCTGTTTTGATATTAGACGAAGCTACAAGTAACTTGGATATTTTGACTGAGAAGCGAATTGTTGATAACCTGATGGCTTT
AGATAAAACCTTGATATTTATTGCTCACCGTTTAACTATTGCAGAGCGTACAGAGCATGTCGTCGTTTTGGATAAAGGAA
AGATCATAGAGCAAGGAACACACAGAGACCTTGTTTCTCAGAATGGCTTTTATGCTCACTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(169-438)

Peptidase C39 family (Peptidase_C39)

(6-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3T8J4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

82.148

100

0.821
  comA Streptococcus mitis SK321

81.729

100

0.817
  comA Streptococcus pneumoniae Rx1

81.729

100

0.817
  comA Streptococcus pneumoniae D39

81.729

100

0.817
  comA Streptococcus pneumoniae R6

81.729

100

0.817
  comA Streptococcus pneumoniae TIGR4

81.45

100

0.815
  comA Streptococcus gordonii str. Challis substr. CH1

78.661

100

0.787
  comA/nlmT Streptococcus mutans UA159

62.901

100

0.629

Multiple sequence alignment