Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GJS32_RS10040 Genome accession   NZ_CP046040
Coordinates   2105454..2106725 (-) Length   423 a.a.
NCBI ID   WP_014623641.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain OH-71905     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2100454..2111725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS32_RS10015 (GJS32_10015) - 2102340..2102639 (-) 300 WP_012516437.1 DUF1292 domain-containing protein -
  GJS32_RS10020 (GJS32_10020) ruvX 2102649..2103068 (-) 420 WP_015898660.1 Holliday junction resolvase RuvX -
  GJS32_RS10025 (GJS32_10025) - 2103065..2103334 (-) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  GJS32_RS10030 (GJS32_10030) spx 2103449..2103847 (-) 399 WP_012516440.1 transcriptional regulator Spx -
  GJS32_RS10035 (GJS32_10035) recA 2104224..2105360 (-) 1137 WP_012516441.1 recombinase RecA Machinery gene
  GJS32_RS10040 (GJS32_10040) cinA 2105454..2106725 (-) 1272 WP_014623641.1 competence/damage-inducible protein A Machinery gene
  GJS32_RS10045 (GJS32_10045) - 2107411..2107701 (-) 291 WP_012516443.1 hypothetical protein -
  GJS32_RS10050 (GJS32_10050) - 2107695..2108267 (-) 573 WP_038674692.1 phosphlipase A2 SlaA -
  GJS32_RS10055 (GJS32_10055) - 2108564..2109409 (+) 846 WP_012516446.1 helix-turn-helix domain-containing protein -
  GJS32_RS10060 (GJS32_10060) - 2109854..2110405 (-) 552 WP_038674690.1 DNA-3-methyladenine glycosylase I -
  GJS32_RS10065 (GJS32_10065) ruvA 2110415..2111011 (-) 597 WP_014623644.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45947.62 Da        Isoelectric Point: 5.3389

>NTDB_id=400494 GJS32_RS10040 WP_014623641.1 2105454..2106725(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKHTARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDGVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKYQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEVQ
LLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTNSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIATLYAFNMVRKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=400494 GJS32_RS10040 WP_014623641.1 2105454..2106725(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTCTATCGGA
AAAAATGGCAGAGCTTGGCATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCATACTGCTAGGACACCAAACAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTGTTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGCTTGATCACTGTAGATGGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGTTAAAGCCTATG
GTAAAAAATGAGCTGGTACCCCTTCTTTCAGCTAGTCACGCTAGTCTGTACTCAAGAGTGCTGCGCTTTTTTGGCATTGG
TGAGAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGTATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGACAACCAAGCATTAGCTGATGAAAGGCTGAATCGACTAGAGGTGCAG
CTCTTATCCATAAGAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCGCG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGTAAGACGATAACAGCAGCTGAAAGCTTAACAGCAGGACTGTTTCAGGCTC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGCATTCCATTGGTTGAGCTACAAAGGCATGGTGTTGTGAGCTCTTTCACAGCTGAGCAAATGGCTGCGCAGGCACG
CTGCTTGACCAATTCGGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGAACTCGAGGAGCAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTCATAGGAGGTCGCAGCCGTTTGGACGTG
CGGTACATTGCTACTCTGTACGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.686

100

0.707
  cinA Streptococcus mitis NCTC 12261

70.264

98.582

0.693
  cinA Streptococcus mitis SK321

70.264

98.582

0.693
  cinA Streptococcus pneumoniae TIGR4

69.784

98.582

0.688
  cinA Streptococcus pneumoniae Rx1

69.784

98.582

0.688
  cinA Streptococcus pneumoniae R6

69.784

98.582

0.688
  cinA Streptococcus pneumoniae D39

69.544

98.582

0.686
  cinA Streptococcus suis isolate S10

53.938

99.054

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

47.129

98.818

0.466

Multiple sequence alignment