Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GJS32_RS03410 Genome accession   NZ_CP046040
Coordinates   718695..720845 (+) Length   716 a.a.
NCBI ID   WP_014622589.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain OH-71905     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 713695..725845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS32_RS03395 (GJS32_03395) - 714129..714623 (+) 495 WP_012679249.1 shikimate kinase -
  GJS32_RS03400 (GJS32_03400) - 714821..716251 (+) 1431 WP_014622587.1 LCP family protein -
  GJS32_RS03405 (GJS32_03405) rlmD 716329..717684 (+) 1356 WP_014622588.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  GJS32_RS03410 (GJS32_03410) comA 718695..720845 (+) 2151 WP_014622589.1 peptide cleavage/export ABC transporter ComA Regulator
  GJS32_RS03415 (GJS32_03415) comB 720854..722215 (+) 1362 WP_014622590.1 bacteriocin secretion accessory protein Regulator
  GJS32_RS03420 (GJS32_03420) - 722594..722866 (+) 273 WP_041788144.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  GJS32_RS10430 - 723148..723531 (+) 384 WP_158306818.1 CPBP family intramembrane glutamic endopeptidase -
  GJS32_RS10435 - 724240..724633 (-) 394 Protein_650 IS481 family transposase -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80650.82 Da        Isoelectric Point: 7.9447

>NTDB_id=400458 GJS32_RS03410 WP_014622589.1 718695..720845(+) (comA) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
MKFKKKHYRSQIDTKDCGVASLAMVFGYYGSYYSLATLRELAKTTQEGTTAFGLVKVAEGEGFETRAIRADMTLFDEDII
YPFIAHVVKNGTLMHYYVVVGCDKKTIHIADPDPSVKMIKMPRERFEKEWTGVSIFIAPTPSYKVHKERKDSLLSFLPIL
SRQKGLITNIVVATLLVTLINIIGSYYLQSIIDTYIPEQVKNTLSIVSVGLVIVYILQQLISYAQEYLLLVLGQRLSIDV
ILSYIKHVFRLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIIIIVSIVLFSQNINLFFISLLALPIYTVI
ILSFMKPFERMNQETMEANATLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVDYLKKSFAYGKAESTQKTLKKLAQLL
LNVAVLWMGANLVMDNKMSLGQLITYNSLLAYFTNPLENLINLQTKLQTAKVANNRLNEVYLVKSEFEETKTVHDLSHFK
GHLTFKNVTYRYGYGKDVLTDIDLSIKPGSKVSFVGISGSGKTTLAKMLVNFFSPTKGEMLLDDVNLEDIDKESLRRYIN
YLPQQPYVFNGTILDNLLLGAKEGTTQEDIFRAVQISEIKADIEAMPLNYQTELTSDGSGISGGQRQRIALARALLTDSP
ILILDEATSSLDVLTEKKIIDNLMALDKTLIFIAHRLTISERTEHIVVLDKGKIIEEGSHRELLAKQGFYAHLVNS

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=400458 GJS32_RS03410 WP_014622589.1 718695..720845(+) (comA) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
ATGAAATTTAAAAAGAAGCATTACAGGTCACAAATTGATACTAAGGACTGCGGTGTTGCGTCATTAGCTATGGTTTTTGG
GTATTACGGATCATATTATTCTTTAGCCACTCTTCGTGAGCTTGCTAAAACTACCCAAGAGGGAACAACAGCATTTGGAT
TGGTCAAGGTTGCTGAAGGAGAAGGATTTGAGACACGTGCCATTCGTGCTGATATGACTTTATTTGATGAAGATATTATC
TATCCATTCATTGCTCACGTTGTTAAGAATGGTACTCTGATGCATTATTACGTGGTTGTCGGATGCGATAAAAAGACAAT
TCATATTGCGGATCCTGATCCGTCAGTTAAGATGATAAAGATGCCACGTGAACGTTTTGAAAAAGAATGGACTGGAGTAT
CAATTTTTATTGCTCCTACGCCTAGTTATAAGGTTCATAAGGAACGGAAGGACAGCTTACTTTCCTTTTTACCAATTTTA
TCTCGTCAAAAAGGGTTAATTACTAATATTGTTGTAGCCACCTTATTAGTTACCTTAATTAATATTATTGGCTCTTACTA
TTTGCAGTCGATTATTGATACCTATATCCCAGAACAAGTAAAAAATACATTGAGTATTGTTTCTGTAGGACTTGTGATTG
TTTATATTTTACAACAATTAATTTCTTATGCTCAAGAGTATTTACTTTTAGTTCTTGGGCAGAGACTGTCTATTGATGTT
ATTTTGTCCTATATTAAGCATGTCTTTCGTCTTCCAATGTCATTCTTTGCGACAAGAAGAACAGGAGAGATTGTATCACG
TTTTACGGATGCCAATTCTATCATTGATGCCTTGGCAAGTACAATCTTATCTATTTTCTTAGATGTTTCCATTATCATTA
TTGTATCGATAGTATTGTTTTCTCAAAATATCAATCTCTTTTTCATTAGTTTATTAGCTTTACCAATTTATACTGTCATT
ATTCTATCGTTTATGAAGCCCTTCGAGCGTATGAATCAAGAAACAATGGAAGCAAATGCTACCTTATCTTCTTCAATTAT
TGAAGATATCAACGGTATTGAGACTATTAAATCATTGACAAGTGAAAAGCAACGTTATCAAAAAATTGATAAAGAATTTG
TTGATTACTTGAAAAAATCTTTTGCTTACGGTAAAGCTGAAAGTACTCAAAAAACATTGAAAAAATTAGCGCAATTGTTA
CTCAATGTAGCAGTCCTTTGGATGGGTGCTAATCTAGTTATGGATAATAAAATGTCTCTTGGGCAATTAATTACCTATAA
TTCTTTACTAGCCTATTTCACAAATCCGTTAGAAAATCTGATAAACCTGCAGACCAAGTTACAAACAGCTAAAGTTGCTA
ATAATCGTTTAAATGAAGTATATCTCGTTAAATCAGAATTCGAAGAAACCAAAACAGTTCATGATTTAAGTCATTTCAAA
GGTCATTTAACGTTTAAAAATGTTACTTACCGTTATGGATACGGAAAAGATGTTTTAACTGATATTGATTTAAGTATTAA
GCCTGGTAGTAAAGTATCTTTTGTTGGTATATCAGGCTCAGGAAAAACAACATTAGCCAAAATGTTAGTCAATTTCTTTA
GTCCTACTAAAGGAGAGATGTTATTAGACGATGTTAACTTAGAAGATATTGATAAAGAAAGTCTACGTCGTTATATCAAC
TATCTGCCACAGCAGCCATATGTTTTTAATGGAACGATTTTAGATAATCTTTTATTAGGTGCTAAAGAAGGAACGACCCA
GGAAGATATCTTCAGAGCAGTTCAGATTTCTGAAATTAAGGCAGATATCGAAGCTATGCCACTTAATTATCAAACGGAAT
TAACATCGGATGGCTCAGGGATATCAGGTGGGCAACGTCAACGTATTGCTTTAGCCCGTGCCTTATTAACAGATTCCCCA
ATTCTCATTCTTGATGAGGCAACCAGTAGTTTAGATGTCTTAACAGAAAAGAAAATTATTGATAATCTCATGGCGCTCGA
TAAAACATTGATATTCATTGCCCATAGATTAACGATTTCAGAGAGAACTGAGCATATTGTAGTGCTAGATAAGGGGAAAA
TTATTGAAGAAGGCAGCCATAGGGAGTTATTGGCTAAACAAGGCTTCTATGCCCATCTTGTCAATAGTTAG

Domains

Predicted by InterProScan.

ABC transporter transmembrane region (ABC_membrane)

(168-437)

ABC transporter (ABC_tran)

(499-649)

Peptidase C39 family (Peptidase_C39)

(6-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

79.916

100

0.8
  comA Streptococcus mitis SK321

79.498

100

0.796
  comA Streptococcus pneumoniae D39

79.358

100

0.795
  comA Streptococcus pneumoniae R6

79.358

100

0.795
  comA Streptococcus pneumoniae Rx1

79.358

100

0.795
  comA Streptococcus pneumoniae TIGR4

79.079

100

0.792
  comA Streptococcus gordonii str. Challis substr. CH1

75.314

100

0.754
  comA/nlmT Streptococcus mutans UA159

63.04

100

0.631

Multiple sequence alignment