Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   GJS32_RS03415 Genome accession   NZ_CP046040
Coordinates   720854..722215 (+) Length   453 a.a.
NCBI ID   WP_014622590.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain OH-71905     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 715854..727215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS32_RS03405 (GJS32_03405) rlmD 716329..717684 (+) 1356 WP_014622588.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  GJS32_RS03410 (GJS32_03410) comA 718695..720845 (+) 2151 WP_014622589.1 peptide cleavage/export ABC transporter ComA Regulator
  GJS32_RS03415 (GJS32_03415) comB 720854..722215 (+) 1362 WP_014622590.1 bacteriocin secretion accessory protein Regulator
  GJS32_RS03420 (GJS32_03420) - 722594..722866 (+) 273 WP_041788144.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  GJS32_RS10430 - 723148..723531 (+) 384 WP_158306818.1 CPBP family intramembrane glutamic endopeptidase -
  GJS32_RS10435 - 724240..724633 (-) 394 Protein_650 IS481 family transposase -
  GJS32_RS03435 (GJS32_03435) - 724866..727175 (+) 2310 WP_154293421.1 DUF4135 domain-containing protein -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 50720.10 Da        Isoelectric Point: 4.9306

>NTDB_id=400459 GJS32_RS03415 WP_014622590.1 720854..722215(+) (comB) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
MYEELLESSEFYQKRYHNFSSRIILPIFGLLIFLVIFLAFMKKEVTLKSQATVEPVKVLAQIQSTSNNTIKTNNLQENKL
VNKDDLLIEYETASEMIQHDSTQDQLNNLKLQKEQLELLKSSVESGISQFPQTDSFGYYKRFEDYLNQRQTLTSNIEQQN
GTIASQNAASQNAQNTIGGLINDTTQKIANYEAAKSAIQNGQVVDVTNPAYSIYSTYIAQSATLLTDVEKTTLMNQVVAQ
LDSQIQQYQTELSNYQIQYSGSGTQQAYNSSLDSQLASLQSQKIAEISQELTALDQKIKELNGGFLLQENTLKETKIKAS
VAGIVHVNPEVIDSTIIPEGTVIAQIFPKLEDEKAVKIETYISSRDITSLKIGDTVKFKTQDSSNKEVTLKSKITSIDSS
ATKTKEGSYFKVVSEAKLSNKELKDLKYGSSGDLVVVTGEKTYLKYYLDKFLN

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=400459 GJS32_RS03415 WP_014622590.1 720854..722215(+) (comB) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
ATGTACGAAGAACTATTAGAAAGCTCGGAATTCTATCAGAAACGTTATCATAATTTTTCAAGTAGAATTATTTTACCAAT
ATTTGGTTTATTGATTTTTTTGGTAATCTTTTTAGCCTTTATGAAAAAGGAAGTTACCCTAAAAAGTCAAGCGACAGTCG
AACCGGTAAAAGTATTAGCTCAAATTCAATCAACTAGTAATAATACGATTAAAACAAATAATCTTCAGGAAAATAAGTTG
GTCAATAAAGATGACTTACTTATCGAATATGAGACAGCTAGTGAAATGATTCAACATGATAGTACTCAAGATCAGTTAAA
TAACCTTAAGCTGCAAAAAGAACAATTGGAATTGTTGAAATCTAGTGTTGAGAGTGGCATAAGCCAGTTTCCTCAAACAG
ATTCCTTTGGTTACTATAAGAGATTTGAAGATTATCTTAACCAACGTCAAACCCTTACTAGTAATATAGAGCAACAAAAT
GGAACAATCGCATCTCAAAATGCAGCCTCTCAAAATGCTCAGAATACTATCGGAGGTCTGATTAATGATACCACTCAAAA
AATAGCCAATTATGAAGCTGCAAAGAGTGCAATCCAAAATGGCCAAGTAGTAGATGTTACTAACCCAGCTTACTCGATAT
ATTCTACGTATATAGCCCAAAGTGCAACATTGCTCACAGATGTTGAAAAGACAACTTTAATGAATCAGGTAGTTGCTCAA
CTTGATTCTCAAATTCAGCAGTACCAGACTGAATTATCAAATTATCAGATTCAGTATTCTGGTTCAGGAACGCAGCAGGC
TTATAATTCGAGTTTAGATAGTCAACTGGCTTCATTGCAATCTCAAAAAATAGCGGAGATAAGCCAGGAATTAACAGCTT
TAGATCAAAAAATTAAAGAATTAAATGGTGGTTTCTTGTTGCAAGAAAATACTTTAAAAGAAACTAAAATTAAGGCTAGT
GTAGCAGGAATCGTCCATGTTAATCCAGAAGTAATTGATTCAACAATTATTCCTGAAGGGACAGTTATTGCACAAATTTT
TCCGAAGCTAGAAGATGAGAAAGCAGTTAAAATTGAGACCTACATATCATCTAGAGATATAACAAGTTTGAAAATTGGTG
ATACGGTTAAGTTCAAAACCCAGGATTCTTCAAATAAAGAAGTGACTTTGAAATCTAAAATCACTAGTATTGACAGTAGT
GCAACGAAGACAAAAGAGGGAAGCTATTTCAAAGTTGTATCAGAAGCAAAATTATCAAATAAAGAATTAAAAGATTTGAA
ATATGGTTCATCAGGTGACTTAGTTGTAGTAACTGGAGAGAAAACTTACCTAAAATACTATCTTGATAAATTTTTAAACT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein (HlyD_3)

(316-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

49.227

100

0.492
  comB Streptococcus mitis SK321

47.903

100

0.479
  comB Streptococcus mitis NCTC 12261

47.903

100

0.479
  comB Streptococcus pneumoniae R6

47.682

100

0.477
  comB Streptococcus pneumoniae Rx1

47.682

100

0.477
  comB Streptococcus pneumoniae D39

47.682

100

0.477
  comB Streptococcus pneumoniae TIGR4

47.241

100

0.472

Multiple sequence alignment