Detailed information NTG0040045

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SGGBAA2069_RS03380
• Genome accession: NC_015215
• Coordinates: 639651..641882 (+)
• Length: 743 a.a.
• NCBI ID: WP_014619988.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 634651..646882

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGBAA2069_RS03355 (SGGBAA2069_c06010)	-	635424..637004 (+)	1581	WP_013642855.1	DEAD/DEAH box helicase	-
SGGBAA2069_RS03360 (SGGBAA2069_c06020)	-	637048..637311 (-)	264	WP_305727931.1	GIY-YIG nuclease family protein	-
SGGBAA2069_RS03365 (SGGBAA2069_c06030)	-	637295..638044 (-)	750	WP_013642857.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
SGGBAA2069_RS03370 (SGGBAA2069_c06040)	-	638152..638898 (+)	747	WP_009853766.1	lysophospholipid acyltransferase family protein	-
SGGBAA2069_RS03375 (SGGBAA2069_c06050)	comEA	638993..639658 (+)	666	WP_013642858.1	helix-hairpin-helix domain-containing protein	Machinery gene
SGGBAA2069_RS03380 (SGGBAA2069_c06060)	comEC/celB	639651..641882 (+)	2232	WP_014619988.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SGGBAA2069_RS03385 (SGGBAA2069_c06070)	-	641944..642132 (+)	189	WP_013642860.1	type II toxin-antitoxin system HicA family toxin	-
SGGBAA2069_RS03390 (SGGBAA2069_c06080)	-	642172..642549 (+)	378	WP_013642861.1	type II toxin-antitoxin system HicB family antitoxin	-
SGGBAA2069_RS03395 (SGGBAA2069_c06090)	-	642633..643211 (+)	579	WP_013642862.1	HD domain-containing protein	-
SGGBAA2069_RS03400 (SGGBAA2069_c06100)	-	643214..643750 (+)	537	WP_231844605.1	hypothetical protein	-
SGGBAA2069_RS12115 (SGGBAA2069_c06110)	-	643792..643944 (+)	153	WP_013642864.1	hypothetical protein	-
SGGBAA2069_RS03405 (SGGBAA2069_c06130)	holA	643996..645033 (+)	1038	WP_009853769.1	DNA polymerase III subunit delta	-
SGGBAA2069_RS03410 (SGGBAA2069_c06140)	sodA	645122..645730 (+)	609	WP_014619989.1	superoxide dismutase SodA	-
SGGBAA2069_RS03415 (SGGBAA2069_c06150)	-	645882..646607 (+)	726	WP_012961667.1	YebC/PmpR family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83882.27 Da
• Isoelectric Point: 8.6237

>NTDB_id=40045 SGGBAA2069_RS03380 WP_014619988.1 639651..641882(+) (comEC/celB) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MIKYFPIKPIQLTFLLILLYYFCFSKMIGCLMFLLLALVFLWQQYGWKTWCQVCLCLSCFAVFFLTKSNQTEQAYQAAPA
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTVVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVYKMTLWEKLHDVRRKAIVSIQRHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGAFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFIVMPN
FLLTTGGILSFTYAFILSFINFDDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSLIF
ILSPLVKLTCFNGCFVFLETVIKNTKAILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVGLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEILVSQGSLTKPDFVAKLQAMKTKVRVVTAGDVLPIMGSHLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELIATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=40045 SGGBAA2069_RS03380 WP_014619988.1 639651..641882(+) (comEC/celB) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
TTGATTAAATATTTTCCCATTAAGCCAATTCAATTGACTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAAT
GATTGGGTGTTTGATGTTTCTCTTGCTAGCCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGACTTGGTGTCAAGTTT
GCTTGTGTTTAAGCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGCAGCACCAGCT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGGGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGGTTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTTATAAGATGACTTTGTGGGAGAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCGGCATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGCATGCAGGTCGGCTTTTTTGTGGGGGCATTCCGCTTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
CATACTACAAATTCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTTTTCTGTTTCGGTGATTCGGAGTTTAATTCAGT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTAGCTTTAACTTTGTTTGTTCTTTTCATAGTTATGCCAAAT
TTTCTGCTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTAACTTTGATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGCTATCACTCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTCTTGGAAACTGTTATCAAGAACACTAAGGC
AATTTTGGGCGGTCCGATTGTTTTTGGGAAACCAAGTCTTGGTATCTTGGTGCTGCTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGGTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACGGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGCGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGCTGACGGATAGCAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAATTCTGGTTAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTGGTGATGTTTTGCCGATTATGGGAAGTCACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTGTTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTAATAGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGACATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTGA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCATCAAGAAACGCTTGAACGCTTCCGAGCACAAAACATGACCATT
TACCGTACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-174)

• Competence protein (Competence) (213-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.695	99.865	0.526
comEC/celB	Streptococcus mitis SK321	52.291	99.865	0.522
comEC/celB	Streptococcus pneumoniae TIGR4	51.144	100	0.511
comEC/celB	Streptococcus pneumoniae Rx1	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae D39	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae R6	50.606	100	0.506
comEC	Lactococcus lactis subsp. cremoris KW2	47.914	100	0.479