Detailed information NTG0400437

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GJS32_RS00280
• Genome accession: NZ_CP046040
• Coordinates: 48059..48973 (+)
• Length: 304 a.a.
• NCBI ID: WP_014622102.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain OH-71905
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 43059..53973

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS32_RS00260 (GJS32_00260)	purE	44088..44576 (+)	489	WP_014622098.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
GJS32_RS00265 (GJS32_00265)	purK	44563..45636 (+)	1074	WP_014622099.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
GJS32_RS00270 (GJS32_00270)	-	45651..45875 (+)	225	WP_014622100.1	hypothetical protein	-
GJS32_RS00275 (GJS32_00275)	purB	46468..47760 (+)	1293	WP_038674659.1	adenylosuccinate lyase	-
GJS32_RS00280 (GJS32_00280)	comR	48059..48973 (+)	915	WP_014622102.1	helix-turn-helix domain-containing protein	Regulator
GJS32_RS10795	comS	49056..49154 (+)	99	WP_200831644.1	quorum-sensing system DWW-type pheromone	Regulator
GJS32_RS00285 (GJS32_00285)	ruvB	49188..50189 (+)	1002	WP_014622103.1	Holliday junction branch migration DNA helicase RuvB	-
GJS32_RS00290 (GJS32_00290)	-	50437..50895 (+)	459	WP_012514717.1	low molecular weight protein-tyrosine-phosphatase	-
GJS32_RS00295 (GJS32_00295)	-	50901..51302 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
GJS32_RS00300 (GJS32_00300)	-	51299..53080 (+)	1782	WP_014622105.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35851.29 Da
• Isoelectric Point: 4.4139

>NTDB_id=400437 GJS32_RS00280 WP_014622102.1 48059..48973(+) (comR) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDVEMAEKCYDKACLFAQLTGDQYLEKKLREEWDKDIKQYQ

Nucleotide

• Length: 915 bp

>NTDB_id=400437 GJS32_RS00280 WP_014622102.1 48059..48973(+) (comR) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCGATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACGTAGA
AATGGCAGAAAAATGTTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTAGAAAAGAAATTAAGAG
AAGAATGGGATAAAGATATAAAACAATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.153	99.013	0.536
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.164	98.355	0.484
comR	Streptococcus suis D9	38.206	99.013	0.378
comR	Streptococcus suis 05ZYH33	38.983	97.039	0.378
comR	Streptococcus suis P1/7	38.983	97.039	0.378