Detailed information NTG0399361

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: GJE17_RS04595
• Genome accession: NZ_CP045930
• Coordinates: 892243..893079 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain AUSMDU00010539
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 887243..898079

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJE17_RS04565 (GJE17_04565)	-	887728..888165 (+)	438	WP_031488279.1	hypothetical protein	-
GJE17_RS04570 (GJE17_04570)	-	888215..889126 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
GJE17_RS04575 (GJE17_04575)	trhA	889243..889893 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
GJE17_RS04580 (GJE17_04580)	-	889890..890330 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
GJE17_RS04585 (GJE17_04585)	ylqF	890549..891397 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
GJE17_RS04590 (GJE17_04590)	-	891387..892178 (+)	792	WP_031488275.1	ribonuclease HII	-
GJE17_RS04595 (GJE17_04595)	dprA	892243..893079 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
GJE17_RS04600 (GJE17_04600)	topA	893186..895315 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
GJE17_RS08620	-	895390..896246 (-)	857	Protein_849	LysR family transcriptional regulator	-
GJE17_RS04615 (GJE17_04615)	-	896286..896831 (+)	546	Protein_850	PTS sugar transporter subunit IIC	-
GJE17_RS04620 (GJE17_04620)	-	896846..897838 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=399361 GJE17_RS04595 WP_031488274.1 892243..893079(+) (dprA) [Streptococcus pyogenes strain AUSMDU00010539]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=399361 GJE17_RS04595 WP_031488274.1 892243..893079(+) (dprA) [Streptococcus pyogenes strain AUSMDU00010539]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363