Detailed information NTG0039713

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: TSC_RS03130
• Genome accession: NC_014974
• Coordinates: 582309..583310 (+)
• Length: 333 a.a.
• NCBI ID: WP_015716548.1
• Uniprot ID: E8PMJ1
• Organism: Thermus scotoductus SA-01
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 577309..588310

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TSC_RS03110 (TSC_c06340)	-	578342..579475 (+)	1134	WP_015716544.1	citrate synthase/methylcitrate synthase	-
TSC_RS03115 (TSC_c06350)	-	579544..580353 (-)	810	WP_015716545.1	molybdopterin-synthase adenylyltransferase MoeB	-
TSC_RS03120 (TSC_c06360)	-	580356..581237 (-)	882	WP_015716546.1	acyltransferase	-
TSC_RS03125 (TSC_c06370)	era	581282..582187 (-)	906	WP_015716547.1	GTPase Era	-
TSC_RS03130 (TSC_c06380)	dprA	582309..583310 (+)	1002	WP_015716548.1	DNA-processing protein DprA	Machinery gene
TSC_RS03135 (TSC_c06390)	-	583350..584258 (-)	909	WP_015716549.1	manganese catalase family protein	-
TSC_RS03140 (TSC_c06400)	-	584361..585257 (+)	897	WP_015716550.1	LysR family transcriptional regulator	-
TSC_RS03145 (TSC_c06410)	-	585295..586248 (+)	954	WP_015716551.1	branched-chain amino acid transaminase	-
TSC_RS03150 (TSC_c06420)	trmH	586238..586813 (-)	576	WP_015716552.1	tRNA (guanosine(18)-2'-O)-methyltransferase TrmH	-
TSC_RS03155 (TSC_c06430)	hisG	586797..587420 (-)	624	WP_015716553.1	ATP phosphoribosyltransferase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 35697.27 Da
• Isoelectric Point: 5.5690

>NTDB_id=39713 TSC_RS03130 WP_015716548.1 582309..583310(+) (dprA) [Thermus scotoductus SA-01]
MDPLALALLPGIGPKRLLELLAEENPLLSLKERFPQVATQLPQAEGEARRERERAEALGVRILGLWEEAFPEGLRRLPQP
PTHLYVQGDLPEEGKAVAIVGTRKASAWALSFTRKLARELSEAGLCVVSGLARGVDREAHLGALEGGGSTLGVLGSALDR
IYPPEHRELARKVALVSEFPFGTGPKPEFFPRRNRIIAGLVRAVIVVEAPMESGALITARYALELGKEVLAVPGRPTDAN
SLGTNRLIQDGAYPVLSAEDVLSYLGFSGKPKKAVELSQEEEGLYALLRQGEALPEDLAQALGVPAEKVLSLLTLLELKG
LAQALPGGRYGAL

Nucleotide

• Length: 1002 bp

>NTDB_id=39713 TSC_RS03130 WP_015716548.1 582309..583310(+) (dprA) [Thermus scotoductus SA-01]
GTGGATCCCTTGGCCCTGGCCCTGCTTCCCGGCATCGGGCCCAAGCGGCTTCTTGAGCTTTTGGCGGAGGAAAACCCCCT
TCTTTCCTTAAAAGAACGCTTTCCCCAGGTGGCAACCCAGCTTCCCCAGGCGGAAGGGGAGGCCAGGCGGGAAAGGGAGC
GGGCGGAGGCCTTGGGGGTACGCATCCTGGGGCTTTGGGAAGAGGCCTTTCCCGAGGGGCTTAGGAGGCTTCCCCAACCT
CCCACCCACCTCTATGTGCAAGGGGATCTTCCGGAGGAAGGGAAGGCGGTGGCCATCGTGGGCACCAGGAAAGCCTCCGC
CTGGGCGCTTTCCTTCACCCGCAAACTTGCCCGGGAGCTTTCCGAGGCCGGGCTTTGCGTGGTTTCCGGCCTGGCCAGGG
GGGTGGATCGGGAGGCCCACCTGGGGGCCCTGGAGGGAGGTGGGTCCACCCTGGGGGTTTTGGGAAGCGCCTTGGACCGC
ATCTATCCTCCCGAGCACCGGGAGCTGGCCCGGAAGGTGGCCCTGGTTTCCGAGTTCCCCTTCGGCACCGGACCCAAGCC
GGAGTTTTTCCCGAGAAGAAACCGCATCATTGCGGGGCTGGTGCGGGCGGTGATCGTGGTGGAGGCCCCCATGGAATCCG
GAGCCCTCATCACCGCCCGGTATGCCCTGGAACTGGGCAAGGAGGTTTTGGCGGTGCCGGGCCGTCCCACCGATGCGAAC
TCCTTGGGGACCAACCGCCTCATCCAGGATGGAGCCTATCCGGTCCTTTCCGCAGAGGACGTTCTTTCCTACCTGGGATT
TTCCGGGAAGCCCAAAAAGGCAGTGGAGCTTTCCCAGGAGGAGGAGGGGCTTTATGCCCTTCTTAGGCAAGGGGAAGCCC
TCCCCGAGGACCTGGCCCAGGCCTTGGGGGTTCCTGCGGAAAAAGTGCTTTCCCTCCTCACCCTGCTGGAGCTTAAGGGG
CTGGCCCAGGCTTTGCCCGGGGGGAGGTATGGGGCGCTTTAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (56-255)

• DprA winged helix domain (DprA_WH) (270-328)

3D structure

• AlphaFold DB: E8PMJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Thermus thermophilus HB27	78.012	99.7	0.778
dprA	Vibrio campbellii strain DS40M4	40.227	100	0.426
dprA	Vibrio cholerae strain A1552	36.842	100	0.399
dprA	Glaesserella parasuis strain SC1401	34.853	100	0.39
dprA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	43.299	87.387	0.378
dprA	Neisseria meningitidis strain C311	39.103	93.694	0.366
dprA	Neisseria meningitidis MC58	39.103	93.694	0.366