Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FSA28_RS00370 Genome accession   NZ_CP044495
Coordinates   57832..58746 (+) Length   304 a.a.
NCBI ID   WP_002291529.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA140     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 52832..63746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA28_RS00345 (FSA28_1894) - 53452..54063 (+) 612 WP_002291527.1 CPBP family intramembrane glutamic endopeptidase -
  FSA28_RS00350 (FSA28_1895) - 54107..54523 (+) 417 WP_002286077.1 SRPBCC family protein -
  FSA28_RS00355 (FSA28_1896) - 54551..55426 (+) 876 WP_002264675.1 hypothetical protein -
  FSA28_RS00360 (FSA28_1897) purB 55443..56741 (+) 1299 WP_002264677.1 adenylosuccinate lyase -
  FSA28_RS00365 (FSA28_1898) - 56761..57447 (+) 687 WP_002291528.1 DNA alkylation repair protein -
  FSA28_RS00370 (FSA28_1899) comR 57832..58746 (+) 915 WP_002291529.1 helix-turn-helix domain-containing protein Regulator
  FSA28_RS00375 (FSA28_1900) - 59281..61122 (-) 1842 WP_002291531.1 carbohydrate-binding domain-containing protein -
  FSA28_RS00380 (FSA28_1901) - 61619..61894 (+) 276 WP_002283786.1 hypothetical protein -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 35284.44 Da        Isoelectric Point: 5.2885

>NTDB_id=390413 FSA28_RS00370 WP_002291529.1 57832..58746(+) (comR) [Streptococcus mutans strain UA140]
MLKDFGKKIKNLRLEKGLTKEAVCRDESQLSIRQLTRIESGQSTPTLNKAVYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide


Download         Length: 915 bp        

>NTDB_id=390413 FSA28_RS00370 WP_002291529.1 57832..58746(+) (comR) [Streptococcus mutans strain UA140]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAACCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCGTGATGA
ATCGCAGTTGTCAATACGGCAGCTGACTAGAATTGAATCAGGACAGTCTACGCCAACTCTTAATAAAGCTGTTTATATTG
CAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAGAATGTTGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGCGACCAACAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTCTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTTAGCAATAAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(9-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

98.355

100

0.984
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.778

94.737

0.5
  comR Streptococcus pyogenes MGAS8232

47.02

99.342

0.467
  comR Streptococcus pyogenes MGAS315

47.157

98.355

0.464
  comR Streptococcus suis P1/7

43.478

98.355

0.428
  comR Streptococcus suis 05ZYH33

43.478

98.355

0.428
  comR Streptococcus suis D9

37

98.684

0.365

Multiple sequence alignment