Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   HKM25_RS00935 Genome accession   NZ_CP053210
Coordinates   175356..175796 (-) Length   146 a.a.
NCBI ID   WP_000861968.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 6A-10     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 170356..180796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS00910 (HKM25_185) - 170617..171903 (+) 1287 WP_000278865.1 response regulator transcription factor -
  HKM25_RS00915 (HKM25_186) - 171955..172488 (+) 534 WP_000729026.1 hypothetical protein -
  HKM25_RS00920 (HKM25_187) nrdI 172566..173036 (+) 471 WP_000849622.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  HKM25_RS00925 (HKM25_188) - 173329..174591 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  HKM25_RS00930 (HKM25_189) - 174901..175359 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  HKM25_RS00935 (HKM25_190) brsR 175356..175796 (-) 441 WP_000861968.1 LytTR family DNA-binding domain-containing protein Regulator
  HKM25_RS00940 (HKM25_192) hexB 176152..178101 (+) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  HKM25_RS00945 (HKM25_193) ribE 178426..178893 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  HKM25_RS00950 (HKM25_194) - 178894..180099 (-) 1206 WP_001818099.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  HKM25_RS00955 (HKM25_195) ribE 180119..180754 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17137.81 Da        Isoelectric Point: 5.9797

>NTDB_id=390370 HKM25_RS00935 WP_000861968.1 175356..175796(-) (brsR) [Streptococcus pneumoniae strain 6A-10]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=390370 HKM25_RS00935 WP_000861968.1 175356..175796(-) (brsR) [Streptococcus pneumoniae strain 6A-10]
ATGAAAGTAGAATTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
TCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment