Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FSA40_RS00355 Genome accession   NZ_CP044493
Coordinates   57335..58249 (+) Length   304 a.a.
NCBI ID   WP_002266376.1    Uniprot ID   -
Organism   Streptococcus mutans strain MD     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 52335..63249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS00330 (FSA40_0065) - 52779..53198 (+) 420 WP_002280110.1 SRPBCC family protein -
  FSA40_RS00335 (FSA40_0066) - 53302..53898 (+) 597 WP_002280109.1 hypothetical protein -
  FSA40_RS00340 (FSA40_0067) - 53920..54651 (+) 732 WP_002280108.1 hypothetical protein -
  FSA40_RS00345 (FSA40_0068) purB 54945..56243 (+) 1299 WP_002263398.1 adenylosuccinate lyase -
  FSA40_RS00350 (FSA40_0069) - 56263..56949 (+) 687 WP_002280106.1 DNA alkylation repair protein -
  FSA40_RS00355 (FSA40_0070) comR 57335..58249 (+) 915 WP_002266376.1 helix-turn-helix domain-containing protein Regulator
  FSA40_RS00360 - 58781..60624 (-) 1844 Protein_48 carbohydrate-binding domain-containing protein -
  FSA40_RS00365 - 60747..62094 (-) 1348 Protein_49 IS3-like element ISSmu1 family transposase -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 35246.44 Da        Isoelectric Point: 5.1281

>NTDB_id=390342 FSA40_RS00355 WP_002266376.1 57335..58249(+) (comR) [Streptococcus mutans strain MD]
MLKDFGKKIKSLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSMPTLNKAIYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide


Download         Length: 915 bp        

>NTDB_id=390342 FSA40_RS00355 WP_002266376.1 57335..58249(+) (comR) [Streptococcus mutans strain MD]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAGCCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCTTGATGA
ATCGCAGTTGTCAACACGGCAGCTGACTAGAATTGAATCAGGACAGTCTATGCCAACTCTTAATAAAGCTATTTATATTG
CAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAAAATGTCGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGTGACCAACAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTTTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTTAGCAATAAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(9-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

98.684

100

0.987
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.778

94.737

0.5
  comR Streptococcus pyogenes MGAS8232

47.351

99.342

0.47
  comR Streptococcus pyogenes MGAS315

47.492

98.355

0.467
  comR Streptococcus suis P1/7

43.478

98.355

0.428
  comR Streptococcus suis 05ZYH33

43.478

98.355

0.428
  comR Streptococcus suis D9

37

98.684

0.365

Multiple sequence alignment