Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FSA31_RS08970 Genome accession   NZ_CP044492
Coordinates   1785525..1786556 (-) Length   343 a.a.
NCBI ID   WP_257646399.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1780525..1791556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS08930 (FSA31_1767) - 1780711..1780956 (-) 246 WP_002265894.1 helix-turn-helix transcriptional regulator -
  FSA31_RS08935 (FSA31_1768) - 1781501..1782700 (-) 1200 WP_002263443.1 acetate kinase -
  FSA31_RS08940 (FSA31_1769) comYH 1782759..1783712 (-) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  FSA31_RS08945 (FSA31_1770) comYG 1783767..1784156 (-) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  FSA31_RS08950 (FSA31_1771) comYF 1784134..1784568 (-) 435 WP_002274770.1 competence type IV pilus minor pilin ComGF Machinery gene
  FSA31_RS08955 (FSA31_1772) comYE 1784555..1784848 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  FSA31_RS08960 (FSA31_1773) comYD 1784820..1785224 (-) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  FSA31_RS08965 (FSA31_1774) comYC 1785211..1785525 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  FSA31_RS08970 (FSA31_1775) comYB 1785525..1786556 (-) 1032 WP_257646399.1 competence type IV pilus assembly protein ComGB Machinery gene
  FSA31_RS08975 (FSA31_1776) comYA 1786492..1787433 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  FSA31_RS08980 (FSA31_1777) - 1787564..1787947 (-) 384 WP_002263434.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39856.51 Da        Isoelectric Point: 9.5151

>NTDB_id=390329 FSA31_RS08970 WP_257646399.1 1785525..1786556(-) (comYB) [Streptococcus mutans strain T8]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEEIWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=390329 FSA31_RS08970 WP_257646399.1 1785525..1786556(-) (comYB) [Streptococcus mutans strain T8]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CACGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGACATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAATATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

99.708

100

0.997
  comYB Streptococcus mutans UA140

99.125

100

0.991
  comYB Streptococcus gordonii str. Challis substr. CH1

59.767

100

0.598
  comGB/cglB Streptococcus mitis NCTC 12261

58.112

98.834

0.574
  comGB/cglB Streptococcus mitis SK321

56.25

97.959

0.551
  comGB/cglB Streptococcus pneumoniae Rx1

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae D39

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae R6

55.655

97.959

0.545
  comGB/cglB Streptococcus pneumoniae TIGR4

55.655

97.959

0.545
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507

Multiple sequence alignment