Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   LPB220_RS07890 Genome accession   NZ_CP044230
Coordinates   1520227..1520928 (-) Length   233 a.a.
NCBI ID   WP_003008151.1    Uniprot ID   -
Organism   Streptococcus sp. LPB0220     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1515227..1525928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB220_RS10810 - 1516217..1516678 (+) 462 WP_024054733.1 hypothetical protein -
  LPB220_RS07870 (LPB220_07875) - 1516941..1517327 (-) 387 WP_150906393.1 YbaN family protein -
  LPB220_RS07875 (LPB220_07880) - 1517361..1517906 (-) 546 WP_049497366.1 hypothetical protein -
  LPB220_RS07880 (LPB220_07885) vicX 1518065..1518874 (-) 810 WP_150906394.1 MBL fold metallo-hydrolase Regulator
  LPB220_RS07885 (LPB220_07890) micB 1518882..1520234 (-) 1353 WP_061591303.1 cell wall metabolism sensor histidine kinase VicK Regulator
  LPB220_RS07890 (LPB220_07895) micA 1520227..1520928 (-) 702 WP_003008151.1 response regulator YycF Regulator
  LPB220_RS07895 (LPB220_07900) - 1521433..1522482 (+) 1050 WP_150906395.1 DUF389 domain-containing protein -
  LPB220_RS07900 (LPB220_07905) thrS 1522694..1524637 (-) 1944 WP_150906396.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26690.49 Da        Isoelectric Point: 4.6027

>NTDB_id=389002 LPB220_RS07890 WP_003008151.1 1520227..1520928(-) (micA) [Streptococcus sp. LPB0220]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFAAENPDIIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADPQLENEADTEIVIGDLHILPDAFLVQKGNKELDLTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=389002 LPB220_RS07890 WP_003008151.1 1520227..1520928(-) (micA) [Streptococcus sp. LPB0220]
ATGAAAAAAATATTAGTAGTTGATGATGAAAAACCAATTTCAGATATTATCAAATTTAACATGGCAAAAGAAGGCTATGA
GGTATTGACAGCCTTTGATGGTCGGGAAGCTTTAGAGGTCTTTGCGGCTGAAAATCCGGATATCATTATTCTAGATTTGA
TGTTGCCAGAGATTGATGGCTTGGAAGTGGCGCGGACGATTCGTAAGACTAGCAATGTGCCGATCATTGTCCTATCTGCT
AAGGATACGGAATTTGATAAGGTCATTGGGCTTGAAATCGGGGCGGATGACTATGTAACCAAACCCTTCTCGAATCGGGA
ATTGCAAGCGCGTGTGAAAGCCTTGTTGCGTCGTTCGGAGTTTGCGGCTGATCCTCAACTTGAAAATGAGGCCGATACGG
AAATTGTCATTGGTGATCTTCACATTCTTCCAGATGCTTTCTTGGTTCAAAAAGGCAACAAAGAATTGGACTTGACCCAT
CGCGAATTTGAATTGCTCTATCACCTTGCGACCCATGTCGGTCAAGTGATGACCCGTGAACACCTTCTTGAGACGGTGTG
GGGCTATGATTACTTTGGTGATGTTCGGACAGTGGACGTGACAGTTCGTCGTTTGCGTGAAAAAATCGAGGACACACCGG
GACGTCCAGAATATATCTTGACCCGCCGTGGTGTCGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.403

100

0.824
  vicR Streptococcus mutans UA159

78.298

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

98.712

0.455
  covR Streptococcus salivarius strain HSISS4

43.668

98.283

0.429
  scnR Streptococcus mutans UA159

36.957

98.712

0.365

Multiple sequence alignment