Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   LPB220_RS05920 Genome accession   NZ_CP044230
Coordinates   1120304..1121152 (-) Length   282 a.a.
NCBI ID   WP_150906117.1    Uniprot ID   A0A5J6LMB6
Organism   Streptococcus sp. LPB0220     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1115304..1126152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB220_RS05905 (LPB220_05910) - 1115685..1116512 (-) 828 WP_150906112.1 alpha/beta hydrolase -
  LPB220_RS05910 (LPB220_05915) trmFO 1116606..1117940 (-) 1335 WP_150906113.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  LPB220_RS05915 (LPB220_05920) topA 1118136..1120217 (-) 2082 WP_150906115.1 type I DNA topoisomerase -
  LPB220_RS05920 (LPB220_05925) dprA/cilB/dalA 1120304..1121152 (-) 849 WP_150906117.1 DNA-processing protein DprA Machinery gene
  LPB220_RS05925 (LPB220_05930) - 1121226..1122143 (-) 918 WP_150906119.1 ROK family protein -
  LPB220_RS05930 (LPB220_05935) - 1122147..1122914 (-) 768 WP_150906121.1 ribonuclease HII -
  LPB220_RS05935 (LPB220_05940) ylqF 1122901..1123752 (-) 852 WP_150906123.1 ribosome biogenesis GTPase YlqF -
  LPB220_RS05940 (LPB220_05945) - 1123864..1125294 (-) 1431 WP_150906125.1 zinc-ribbon domain-containing protein -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31729.52 Da        Isoelectric Point: 6.3432

>NTDB_id=388996 LPB220_RS05920 WP_150906117.1 1120304..1121152(-) (dprA/cilB/dalA) [Streptococcus sp. LPB0220]
MEKFEIFKLKEAGLSNEQVLRVLDYCRKEQVLPSLEEIARIARCRSILHFVDKYRQLDEDHLHKEFERFPSLSIFDPEYP
EELLQIYNPPVLLFYQGDLELLTRPKIAVVGARETTREGVRSVEKIIKELGNELVIVSGLAKGIDATAHYASIRNGGKTI
GVIGTGLDVFYPKSNQRLQAHMGEHHLILSEYGPGQAPLKFHFPERNRIIAGLCQAVIVAEARLRSGSLITCERAMEEGR
DVFAIPGNILDGKSAGCHHLIQEGAKLVTSGQDILDELKYEL

Nucleotide


Download         Length: 849 bp        

>NTDB_id=388996 LPB220_RS05920 WP_150906117.1 1120304..1121152(-) (dprA/cilB/dalA) [Streptococcus sp. LPB0220]
ATGGAGAAATTTGAAATCTTTAAATTAAAAGAAGCCGGTTTATCAAATGAGCAAGTCTTGAGAGTCTTGGACTACTGTAG
GAAAGAGCAAGTCTTACCAAGCTTAGAAGAGATAGCAAGGATCGCTCGCTGTCGCAGTATCCTTCATTTTGTAGACAAAT
ACCGGCAACTAGATGAAGACCATTTACACAAGGAGTTTGAACGGTTCCCATCTCTATCCATTTTTGATCCAGAATACCCT
GAGGAATTGCTACAGATCTACAATCCTCCTGTACTCCTTTTTTACCAAGGGGATTTGGAGCTGTTAACCAGACCGAAGAT
CGCAGTTGTTGGAGCTCGGGAGACCACGCGAGAAGGGGTTCGTTCTGTAGAGAAGATTATTAAGGAACTTGGGAATGAAT
TGGTCATTGTTAGTGGACTTGCTAAGGGAATTGATGCGACCGCTCATTATGCCAGTATCCGAAATGGTGGCAAGACCATC
GGAGTGATAGGAACGGGACTGGATGTCTTTTATCCTAAGAGCAATCAAAGACTGCAGGCGCATATGGGGGAACACCATCT
GATCTTGAGCGAGTATGGTCCAGGTCAGGCACCACTTAAGTTTCATTTTCCTGAGCGAAACCGCATCATTGCAGGTCTCT
GTCAGGCAGTGATTGTGGCAGAAGCTCGACTCCGTTCAGGCAGTTTGATTACTTGTGAGCGTGCTATGGAAGAAGGACGA
GACGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAATCTGCAGGCTGCCATCATCTGATTCAAGAAGGTGCAAAGCT
TGTCACCTCAGGCCAGGACATTCTTGATGAATTGAAATACGAATTGTGA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(72-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5J6LMB6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

65.357

99.291

0.649
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

65

99.291

0.645
  dprA/cilB/dalA Streptococcus pneumoniae D39

65

99.291

0.645
  dprA/cilB/dalA Streptococcus pneumoniae R6

65

99.291

0.645
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

65

99.291

0.645
  dprA/cilB/dalA Streptococcus mitis SK321

64.643

99.291

0.642
  dprA Streptococcus mutans UA159

62.143

99.291

0.617
  dprA Lactococcus lactis subsp. cremoris KW2

53.025

99.645

0.528
  dprA Bacillus subtilis subsp. subtilis str. 168

40.559

100

0.411
  dprA Legionella pneumophila strain ERS1305867

44.017

82.979

0.365

Multiple sequence alignment