Detailed information NTG0388835

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: F5989_RS05110
• Genome accession: NZ_CP044221
• Coordinates: 1045698..1047980 (-)
• Length: 760 a.a.
• NCBI ID: WP_002274031.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NCH105
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1040698..1052980

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F5989_RS05095 (F5989_05175)	-	1040747..1042222 (-)	1476	WP_002273282.1	BglG family transcription antiterminator	-
F5989_RS05100 (F5989_05180)	-	1042761..1044425 (-)	1665	WP_002289832.1	BglG family transcription antiterminator	-
F5989_RS05105 (F5989_05185)	comB/nlmE	1044782..1045684 (-)	903	WP_002263524.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
F5989_RS05110 (F5989_05190)	comA/nlmT	1045698..1047980 (-)	2283	WP_002274031.1	peptide cleavage/export ABC transporter	Regulator
F5989_RS05115 (F5989_05195)	-	1048409..1048585 (-)	177	WP_019319593.1	hypothetical protein	-
F5989_RS05120 (F5989_05200)	-	1048634..1049041 (-)	408	WP_002263726.1	hypothetical protein	-
F5989_RS05125 (F5989_05205)	-	1049066..1049284 (-)	219	WP_002278706.1	Blp family class II bacteriocin	-
F5989_RS05130 (F5989_05215)	-	1050364..1050642 (-)	279	WP_002264456.1	hypothetical protein	-
F5989_RS05135 (F5989_05220)	-	1050880..1051089 (-)	210	WP_002263944.1	hypothetical protein	-
F5989_RS05140 (F5989_05225)	-	1051574..1051735 (-)	162	WP_162470319.1	hypothetical protein	-
F5989_RS05150 (F5989_05235)	-	1051949..1052224 (-)	276	WP_024781591.1	hypothetical protein	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 85112.79 Da
• Isoelectric Point: 8.9095

>NTDB_id=388835 F5989_RS05110 WP_002274031.1 1045698..1047980(-) (comA/nlmT) [Streptococcus mutans strain NCH105]
MKQVIYVVLIVIAVNILLEVIKRVTKRGGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIA
YLRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPS
VKVTRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEY
IPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQII
DAVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMET
IKSLTSESTRYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSN
PIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLV
GASGSGKTTLAKLIVNFYEPNKGIVRINGNDLKVIDKTALRRHISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACE
IAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILTEKKIISNLLQMTEKTIIFVAH
RLSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2283 bp

>NTDB_id=388835 F5989_RS05110 WP_002274031.1 1045698..1047980(-) (comA/nlmT) [Streptococcus mutans strain NCH105]
ATGAAACAAGTTATTTATGTTGTTTTAATCGTCATAGCCGTTAACATTCTCTTAGAGGTTATCAAAAGAGTAACAAAAAG
GGGAGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTAGTAC
CTCAGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTACGGATCTAACTACTCTATCGCT
TATCTGCGGGAACTCTCAAAGACTAACAAGCAGGGAACAACAGCTCTTGGCATTGTTGAAGCTGCTAAAAAGTTAGGCTT
TGAAACACGCTCTATCAAGGCGGATATGACGCTTTTTGATTATAATGATTTGACCTATCCTTTTATCGTCCATGTGATTA
AAGGAAAACGTCTGCAGCATTATTATGTCGTCTATGGCAGCCAGAATAATCAGCTGATTATTGGAGATCCTGATCCTTCA
GTTAAGGTGACTAGGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGCCTTGCAATTTTCCTAGCTCCTCAGCCTAA
CTATAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCTAATTTCTTCCCGTTGATCTTTAAGCAGAAAGCTTTGATGACTT
ATATTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTAC
ATTCCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGGTCATGGC
TTTTGCAAAAGAATACCTCTTGGCCGTACTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATCAAACATATTT
TTACGCTTCCTATGTCTTTCTTTGCGACAAGGCGAACAGGAGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATT
GATGCTGTAGCGTCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTAATTTTGGTTGGCGGGGTTTTGTTGGCGCA
AAACAATAACCTTTTCTTTCTAACCTTGCTCTCCATTCCGATTTATGCCATCATTATTTTTGCTTTCTTGAAACCCTTTG
AGAAAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGATATCAATGGGATGGAAACC
ATTAAATCACTCACAAGTGAGTCCACTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAA
GCTACACAAGTATAGTGCCATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATCCTCAATGTTGTCATTCTCTGGTATG
GCTCTCGTCTAGTTATGGATAATAAAATCTCAGTTGGTCAGCTTATCACCTTTAATGCTTTGCTGTCTTATTTCTCAAAT
CCAATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAGGTCTATCT
TGTCGAATCTGAATTTGAAAAAGACGGCGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAAAATCTTT
CTTATAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGTCTAGTT
GGAGCCAGTGGTTCTGGTAAGACAACTTTGGCTAAACTGATTGTCAATTTCTACGAGCCTAACAAGGGGATTGTTCGAAT
CAATGGCAATGATTTAAAAGTTATTGATAAGACAGCTTTGCGGCGGCATATTAGCTATTTGCCGCAACAGGCCTATGTTT
TTAGTGGCTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCTTGTGAA
ATTGCTGAAATCCGCTCGGACATTGAACAAATGCCTCAGGGCTATCAGACAGAGTTATCAGATGGTGCCGGTATTTCTGG
CGGTCAAAAACAGCGGATTGCTTTAGCTAGGGCCTTATTAACACAGGCACCGGTTTTGATTCTGGATGAAGCCACCAGCA
GTCTTGATATTTTGACAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACAATAATTTTTGTTGCCCAC
CGCTTAAGCATTTCACAGCGTACTGACGAAGTCATTGTCATGGATCAAGGAAAAATTGTTGAACAAGGCACTCATAAGGA
ACTTTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (212-481)

• ABC transporter (ABC_tran) (544-693)

• Peptidase C39 family (Peptidase_C39) (50-186)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	99.737	100	0.997
comA	Streptococcus mitis NCTC 12261	65.411	94.342	0.617
comA	Streptococcus pneumoniae Rx1	64.854	94.342	0.612
comA	Streptococcus pneumoniae D39	64.854	94.342	0.612
comA	Streptococcus pneumoniae R6	64.854	94.342	0.612
comA	Streptococcus mitis SK321	64.714	94.342	0.611
comA	Streptococcus pneumoniae TIGR4	64.575	94.342	0.609
comA	Streptococcus gordonii str. Challis substr. CH1	64.435	94.342	0.608