Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FOB62_RS05305 Genome accession   NZ_CP044102
Coordinates   1047973..1049196 (-) Length   407 a.a.
NCBI ID   WP_003054444.1    Uniprot ID   A0A9X8T5D3
Organism   Streptococcus dysgalactiae strain FDAARGOS_654     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1042973..1054196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB62_RS05280 (FOB62_05280) - 1043459..1043833 (-) 375 WP_003054451.1 helix-turn-helix transcriptional regulator -
  FOB62_RS05285 (FOB62_05285) - 1043958..1044155 (-) 198 WP_003054469.1 DUF951 family protein -
  FOB62_RS05290 (FOB62_05290) dnaN 1044229..1045365 (-) 1137 WP_003060971.1 DNA polymerase III subunit beta -
  FOB62_RS05295 (FOB62_05295) dnaA 1045519..1046874 (-) 1356 WP_003054481.1 chromosomal replication initiator protein DnaA -
  FOB62_RS05300 (FOB62_05300) spo0J 1047108..1047884 (-) 777 WP_003054458.1 ParB/RepB/Spo0J family partition protein Regulator
  FOB62_RS05305 (FOB62_05305) htrA 1047973..1049196 (-) 1224 WP_003054444.1 trypsin-like peptidase domain-containing protein Regulator
  FOB62_RS05310 (FOB62_05310) rlmH 1049408..1049887 (+) 480 WP_003057960.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FOB62_RS05320 (FOB62_05320) - 1050131..1051114 (-) 984 WP_014612660.1 IS30 family transposase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42746.35 Da        Isoelectric Point: 7.3920

>NTDB_id=387876 FOB62_RS05305 WP_003054444.1 1047973..1049196(-) (htrA) [Streptococcus dysgalactiae strain FDAARGOS_654]
MPSMKHILKSLSVLLIGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=387876 FOB62_RS05305 WP_003054444.1 1047973..1049196(-) (htrA) [Streptococcus dysgalactiae strain FDAARGOS_654]
ATGCCAAGTATGAAACATATCTTAAAATCCTTAAGTGTTTTACTAATTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTTAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTGGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGGATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGACTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAATCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGATGTTATTAAAATTATTAAACAGCTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGATTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(109-254)

PDZ domain (PDZ_2)

(301-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.634

99.263

0.612
  htrA Streptococcus gordonii str. Challis substr. CH1

55.473

98.771

0.548
  htrA Streptococcus mitis NCTC 12261

53.317

100

0.533
  htrA Streptococcus pneumoniae Rx1

53.071

100

0.531
  htrA Streptococcus pneumoniae D39

53.071

100

0.531
  htrA Streptococcus pneumoniae R6

53.071

100

0.531
  htrA Streptococcus pneumoniae TIGR4

53.071

100

0.531

Multiple sequence alignment