Detailed information NTG0387772

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: FOB76_RS08620
• Genome accession: NZ_CP044093
• Coordinates: 1685451..1686287 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain FDAARGOS_668
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1680451..1691287

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB76_RS08595 (FOB76_08600)	-	1680670..1681662 (-)	993	WP_002989762.1	D-lactate dehydrogenase	-
FOB76_RS08600 (FOB76_08605)	-	1681677..1682243 (-)	567	Protein_1599	PTS sugar transporter subunit IIC	-
FOB76_RS09520	-	1682283..1683140 (+)	858	Protein_1600	LysR family transcriptional regulator	-
FOB76_RS08615 (FOB76_08620)	topA	1683215..1685344 (-)	2130	WP_002989768.1	type I DNA topoisomerase	-
FOB76_RS08620 (FOB76_08625)	dprA	1685451..1686287 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
FOB76_RS08625 (FOB76_08630)	-	1686352..1687143 (-)	792	WP_002989771.1	ribonuclease HII	-
FOB76_RS08630 (FOB76_08635)	ylqF	1687133..1687981 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
FOB76_RS08635 (FOB76_08640)	-	1688200..1688640 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
FOB76_RS08640 (FOB76_08645)	-	1688637..1689287 (+)	651	WP_002984629.1	hemolysin III family protein	-
FOB76_RS08645 (FOB76_08650)	-	1689404..1690315 (+)	912	WP_002989777.1	diacylglycerol kinase family protein	-
FOB76_RS08650 (FOB76_08655)	-	1690365..1690805 (-)	441	WP_024623381.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=387772 FOB76_RS08620 WP_002989770.1 1685451..1686287(-) (dprA) [Streptococcus pyogenes strain FDAARGOS_668]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=387772 FOB76_RS08620 WP_002989770.1 1685451..1686287(-) (dprA) [Streptococcus pyogenes strain FDAARGOS_668]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367