Detailed information NTG0387678

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FOB77_RS03780
• Genome accession: NZ_CP044091
• Coordinates: 682534..683436 (-)
• Length: 300 a.a.
• NCBI ID: WP_000912098.1
• Uniprot ID: A0AAD2WWZ7
• Organism: Streptococcus agalactiae strain FDAARGOS_669
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 677534..688436

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB77_RS03760 (FOB77_03760)	-	678496..680274 (-)	1779	WP_001220911.1	acyltransferase family protein	-
FOB77_RS03765 (FOB77_03765)	-	680271..680651 (-)	381	WP_000787702.1	membrane protein	-
FOB77_RS03770 (FOB77_03770)	-	680658..681095 (-)	438	WP_000754817.1	low molecular weight protein-tyrosine-phosphatase	-
FOB77_RS03775 (FOB77_03775)	ruvB	681247..682245 (-)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	-
FOB77_RS03780 (FOB77_03780)	comR	682534..683436 (-)	903	WP_000912098.1	helix-turn-helix domain-containing protein	Regulator
FOB77_RS03785 (FOB77_03785)	purB	683589..684887 (-)	1299	WP_000893937.1	adenylosuccinate lyase	-
FOB77_RS03790 (FOB77_03790)	-	684973..686076 (-)	1104	WP_001867169.1	DUF6287 domain-containing protein	-
FOB77_RS03795 (FOB77_03795)	-	686442..686699 (-)	258	WP_000590468.1	hypothetical protein	-
FOB77_RS03800 (FOB77_03800)	purK	686709..687782 (-)	1074	WP_001048172.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
FOB77_RS03805 (FOB77_03805)	purE	687769..688260 (-)	492	WP_001875905.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35606.08 Da
• Isoelectric Point: 6.5030

>NTDB_id=387678 FOB77_RS03780 WP_000912098.1 682534..683436(-) (comR) [Streptococcus agalactiae strain FDAARGOS_669]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YKLLRTPTYGDANRLAVREAYFDEIYEVFYEELPEDERLIIDCMQSKLDVHFSVNDNFGITILHDYFDQIKKKKEYTTND
FVMIDLYLLCFSINYGMKSLYSLENYHFIMSKLLEQDNLLPEDNFQLNNVLLNHVELAFQFKQKKYVQQIIHRSNAIMTE
IHDFQKRPILSLIEWKYLLIIEKDRTKAETCFKQSILFAELIGDLYLKGKLIEEWNKDLT

Nucleotide

• Length: 903 bp

>NTDB_id=387678 FOB77_RS03780 WP_000912098.1 682534..683436(-) (comR) [Streptococcus agalactiae strain FDAARGOS_669]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TACAAATTGTTGCGTACCCCGACTTACGGAGATGCTAATAGACTTGCAGTTAGAGAAGCATATTTTGATGAAATCTATGA
AGTATTTTATGAGGAGCTCCCAGAAGATGAAAGACTAATTATTGATTGTATGCAATCAAAATTAGATGTTCATTTTTCTG
TTAATGATAATTTTGGAATCACTATTTTACATGACTACTTTGATCAAATTAAGAAAAAAAAGGAATATACCACAAATGAT
TTTGTTATGATAGATTTATATTTACTTTGCTTTTCTATTAACTATGGAATGAAGAGCTTGTATTCTTTAGAGAACTATCA
TTTTATTATGTCAAAATTGTTAGAGCAAGATAATTTACTTCCTGAGGATAATTTTCAATTGAACAACGTTTTATTAAATC
ATGTCGAATTAGCTTTTCAATTTAAGCAGAAAAAATATGTACAGCAAATTATTCATAGAAGTAATGCTATTATGACAGAA
ATCCATGATTTTCAAAAAAGACCAATACTAAGCTTAATAGAGTGGAAATATTTATTAATTATTGAAAAAGATAGAACAAA
AGCAGAAACATGTTTTAAACAATCAATTCTATTTGCAGAGTTAATAGGTGATCTATATTTAAAAGGAAAATTAATAGAGG
AGTGGAATAAAGATTTAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-295)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	59.375	96	0.57
comR	Streptococcus mutans UA159	52.174	99.667	0.52
comR	Streptococcus pyogenes MGAS8232	50.166	100	0.503
comR	Streptococcus pyogenes MGAS315	47.667	100	0.477
comR	Streptococcus suis P1/7	40.067	99	0.397
comR	Streptococcus suis 05ZYH33	40.067	99	0.397
comR	Streptococcus suis D9	36.184	100	0.367