Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   FOB78_RS03735 Genome accession   NZ_CP044090
Coordinates   719674..720516 (+) Length   280 a.a.
NCBI ID   WP_001015240.1    Uniprot ID   Q8DZU1
Organism   Streptococcus agalactiae strain FDAARGOS_670     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 720636..721769 719674..720516 flank 120


Gene organization within MGE regions


Location: 719674..721769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB78_RS03735 (FOB78_03735) dprA 719674..720516 (+) 843 WP_001015240.1 DNA-processing protein DprA Machinery gene
  FOB78_RS03740 (FOB78_03740) - 720636..721769 (+) 1134 WP_000564846.1 ISAs1-like element IS1548 family transposase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31294.36 Da        Isoelectric Point: 9.3802

>NTDB_id=387604 FOB78_RS03735 WP_001015240.1 719674..720516(+) (dprA) [Streptococcus agalactiae strain FDAARGOS_670]
MNHFELFKLKKAGLTNLNIHNIINYLKKNSLTSLSVRNMAVVSKCKNPTFFIENYKQLDLKKLRQEFKKFPVLSILDSNY
PLELKEIYNPPVLLFYQGNIELLSKPKLAVVGARQASQIGCQSVKKIIKETNNQFVIVSGLARGIDTAAHVSALKNGGSS
IAVIGSGLDVYYPTENKKLQEYMSYNHLVLSEYFTGEQPLKFHFPERNRIIAGLCQGIVVAEAKMRSGSLITCERALEEG
REVFAIPGNIIDGKSDGCHHLIQEGAKCIISGKDILSEYQ

Nucleotide


Download         Length: 843 bp        

>NTDB_id=387604 FOB78_RS03735 WP_001015240.1 719674..720516(+) (dprA) [Streptococcus agalactiae strain FDAARGOS_670]
ATGAATCATTTTGAACTATTTAAGCTTAAAAAAGCTGGATTAACAAATCTTAATATCCACAATATTATCAACTATCTCAA
AAAGAATAGTTTAACTTCTCTATCTGTTCGCAATATGGCCGTAGTATCAAAATGTAAAAATCCTACTTTCTTTATAGAAA
ATTATAAACAGCTAGACCTTAAAAAACTTCGACAAGAATTCAAAAAATTTCCAGTTCTATCGATTTTGGATTCTAACTAT
CCTTTAGAGTTAAAAGAAATATATAATCCACCAGTTCTACTTTTTTATCAGGGTAATATTGAACTTCTATCTAAACCTAA
ATTAGCTGTAGTGGGGGCAAGACAGGCATCTCAGATAGGTTGTCAGTCTGTTAAAAAGATTATCAAGGAGACTAACAATC
AATTTGTTATCGTAAGTGGTTTAGCGCGTGGCATTGATACAGCAGCACATGTTAGTGCTTTAAAAAATGGCGGCAGTAGT
ATAGCTGTTATCGGGAGTGGTTTAGATGTTTATTATCCAACGGAGAATAAGAAACTTCAAGAATATATGTCATATAATCA
TCTCGTATTATCAGAATATTTTACCGGAGAACAACCCTTGAAATTTCATTTCCCCGAACGTAACCGTATTATTGCAGGGC
TGTGTCAAGGTATTGTGGTTGCCGAAGCTAAGATGAGATCTGGAAGTTTAATTACCTGTGAAAGAGCATTAGAAGAGGGA
CGAGAAGTTTTTGCCATTCCCGGAAATATTATCGATGGCAAATCAGATGGATGCCACCATCTTATCCAAGAAGGAGCTAA
ATGCATTATTTCAGGAAAAGATATCCTTTCTGAATATCAGTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(69-270)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DZU1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

70.251

99.643

0.7
  dprA/cilB/dalA Streptococcus mitis SK321

62.5

100

0.625
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

61.786

100

0.618
  dprA/cilB/dalA Streptococcus pneumoniae D39

61.786

100

0.618
  dprA/cilB/dalA Streptococcus pneumoniae R6

61.786

100

0.618
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

61.786

100

0.618
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

61.429

100

0.614
  dprA Lactococcus lactis subsp. cremoris KW2

60.932

99.643

0.607
  dprA Latilactobacillus sakei subsp. sakei 23K

42.231

89.643

0.379

Multiple sequence alignment