Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   F1539_RS07200 Genome accession   NZ_CP043772
Coordinates   1412930..1414267 (-) Length   445 a.a.
NCBI ID   WP_013526477.1    Uniprot ID   -
Organism   Haemophilus influenzae biotype aegyptius strain HE24/F3037     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1407930..1419267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1539_RS07175 (F1539_07180) - 1409660..1409932 (-) 273 WP_013526482.1 HU family DNA-binding protein -
  F1539_RS07180 (F1539_07185) - 1410072..1410662 (-) 591 WP_013526481.1 YjaG family protein -
  F1539_RS07185 (F1539_07190) nudC 1410698..1411492 (-) 795 WP_013526480.1 NAD(+) diphosphatase -
  F1539_RS07190 (F1539_07195) nfuA 1411559..1412155 (-) 597 WP_013526479.1 Fe-S biogenesis protein NfuA -
  F1539_RS07195 (F1539_07200) - 1412231..1412917 (-) 687 WP_013526478.1 ComF family protein -
  F1539_RS07200 (F1539_07205) comE 1412930..1414267 (-) 1338 WP_013526477.1 type IV pilus secretin PilQ family protein Machinery gene
  F1539_RS07205 (F1539_07210) comD 1414277..1414690 (-) 414 WP_013526476.1 pilus assembly protein PilP Machinery gene
  F1539_RS07210 (F1539_07215) comC 1414687..1415208 (-) 522 WP_041174979.1 competence protein ComC Machinery gene
  F1539_RS07215 (F1539_07220) comB 1415205..1415711 (-) 507 WP_013526474.1 hypothetical protein Machinery gene
  F1539_RS07220 (F1539_07225) comA 1415712..1416509 (-) 798 WP_013526473.1 pilus assembly protein PilM Machinery gene
  F1539_RS07225 (F1539_07230) - 1416608..1419208 (+) 2601 WP_013526472.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49026.34 Da        Isoelectric Point: 8.2552

>NTDB_id=385845 F1539_RS07200 WP_013526477.1 1412930..1414267(-) (comE) [Haemophilus influenzae biotype aegyptius strain HE24/F3037]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVIGDTLENKISLKLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPVGSITFDDRSN
LLVIQDDPRSVQNIKKLISEMDKPIEQIAIEARIVTITDESLKELGIRWGIFNPTENARRVAGSLAGNSFENIADNLNVN
FATTATPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLAALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=385845 F1539_RS07200 WP_013526477.1 1412930..1414267(-) (comE) [Haemophilus influenzae biotype aegyptius strain HE24/F3037]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTCTAGTGTGTTTTTGTTTGCCCTTAATTGTTTTTGCTAATCCAAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCGCCTTTAGCCCAAACATTGGAACAGTTGGCTTTTCAACAAGATG
TAAATTTAGTGATTGGAGATACATTGGAAAACAAGATCTCTTTAAAATTAGACAATATTGATATGCCACGTTTGCTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTATTATCTGAATGGAGGGCAATCAGGCAAAGG
TCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGTGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACCACAGGAAGTGGCTCTTTACTTTCACCCGTTGGGAGCATTACCTTTGATGATCGTAGTAAT
TTGCTAGTTATTCAGGATGATCCTCGTTCTGTACAAAATATCAAAAAACTGATTTCTGAAATGGATAAGCCTATTGAGCA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCATTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGTCTTGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGGCGACACCTGCTGGCTCGATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTCGATTTAGAATT
AAGCGCGTTAGAGCGTGAAAATAATGTGGAAATTATCGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAAGGTACAGAAATTCCTTATGTTGTGAGTAATACTCGTAACGATACACAATCTGTGGAATTTCGCGAGGCGGTG
CTAGGTTTGGAAGTCACTCCACATATTTCCAAAGATAATAATATTTTGCTTGATTTATTAGTGAGTCAAAATTCCCCCGG
TTCTCGTGTCGCTTATGGACAAAACGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACTATTGTGCTTGGTGGCGTGTTCCACGATACGATCACTAAAAGCGAAGATAAAGTGCCATTACTTGGCGATATA
CCCGTCATTAAACGATTATTCAGCAAAGAAAGCGAACGACATCAAAAACGTGAGTTAGTGATTTTCGTGACGCCGCATAT
TTTAAAAGCAGGAGAAACGTTAGCGGCCTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

96.854

100

0.969
  comE Haemophilus influenzae 86-028NP

95.056

100

0.951
  comE Glaesserella parasuis strain SC1401

52.706

95.506

0.503
  pilQ Vibrio campbellii strain DS40M4

42.482

94.157

0.4
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.748

92.584

0.387
  pilQ Vibrio cholerae strain A1552

41.748

92.584

0.387

Multiple sequence alignment