Detailed information NTG0384776

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: FTN78_RS06995
• Genome accession: NZ_CP043523
• Coordinates: 1366905..1367552 (-)
• Length: 215 a.a.
• NCBI ID: WP_010906131.1
• Uniprot ID: A0A3N6KQH1
• Organism: Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1361905..1372552

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FTN78_RS06970 (FTN78_chr1383)	atpF	1361975..1362481 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
FTN78_RS06975 (FTN78_chr1384)	atpB	1362496..1363209 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
FTN78_RS06980 (FTN78_chr1385)	-	1363254..1363469 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
FTN78_RS06985 (FTN78_chr1386)	-	1363653..1364429 (-)	777	WP_004255244.1	alpha/beta hydrolase family protein	-
FTN78_RS06990 (FTN78_chr1387)	comEC	1364714..1366924 (-)	2211	WP_010906130.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FTN78_RS06995 (FTN78_chr1388)	comEA	1366905..1367552 (-)	648	WP_010906131.1	ComEA family DNA-binding protein	Machinery gene
FTN78_RS07000 (FTN78_chr1389)	-	1367612..1368973 (-)	1362	WP_021214597.1	ABC transporter permease	-
FTN78_RS07005 (FTN78_chr1390)	-	1368970..1369902 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
FTN78_RS07010 (FTN78_chr1391)	-	1370007..1370405 (-)	399	WP_004255236.1	hypothetical protein	-
FTN78_RS07015 (FTN78_chr1392)	-	1370509..1371072 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-
FTN78_RS07020 (FTN78_chr1393)	-	1371245..1372423 (-)	1179	WP_021214596.1	SLC13 family permease	-

Sequence

Protein

• Length: 215 a.a.
• Molecular weight: 23624.76 Da
• Isoelectric Point: 4.8659

>NTDB_id=384776 FTN78_RS06995 WP_010906131.1 1366905..1367552(-) (comEA) [Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96]
MDKILEKVKEYWKMIVLVVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVSKFSEPNEKSVSKIMVDLKGAVTKP
NVYQISSDERLVDLIKEAGGFTDQADQKSINLSAKLKDEEVIYVPKIGENSSTENTDSSANSVTSQVSTTTEKININQAD
LTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTLEKLKDELCFE

Nucleotide

• Length: 648 bp

>NTDB_id=384776 FTN78_RS06995 WP_010906131.1 1366905..1367552(-) (comEA) [Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96]
ATGGATAAGATTTTAGAAAAAGTAAAAGAATATTGGAAAATGATTGTTTTAGTTGTTTGTGGGCTCATTGCTGGTGGGAT
TTTTTACGTTTTAACCAACGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT
CTGTCAGTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAAGGTGCGGTAACAAAGCCT
AATGTCTATCAAATTTCGTCAGATGAACGTCTAGTTGATTTAATTAAAGAAGCTGGTGGTTTTACTGACCAAGCTGACCA
GAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTGGTGAAAATTCAAGCACAG
AAAATACTGACAGCTCTGCTAATTCGGTCACTAGTCAAGTCTCAACAACCACTGAAAAAATAAATATCAATCAAGCAGAT
TTGACTGAACTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATCGATTTTCGGACGAAAAATGGTGA
TTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTAGAAAAATTGAAAGATGAGTTGTGTT
TTGAATAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (70-125)

• Helix-hairpin-helix motif (HHH_3) (151-212)

3D structure

• AlphaFold DB: A0A3N6KQH1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Lactococcus lactis subsp. cremoris KW2	76.147	100	0.772
comEA/celA/cilE	Streptococcus mitis SK321	44.907	100	0.451
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.578	100	0.442
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.553	100	0.423
comEA/celA/cilE	Streptococcus pneumoniae D39	41.553	100	0.423
comEA/celA/cilE	Streptococcus pneumoniae R6	41.553	100	0.423
comEA/celA/cilE	Streptococcus mitis NCTC 12261	41.743	100	0.423
comEA	Latilactobacillus sakei subsp. sakei 23K	36.564	100	0.386