Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FY406_RS03955 Genome accession   NZ_CP043405
Coordinates   804102..804818 (+) Length   238 a.a.
NCBI ID   WP_003090200.1    Uniprot ID   A0A7X9LCM5
Organism   Streptococcus ratti strain ATCC 31377     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 799102..809818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS03940 (FY406_03940) comR/comR1 799994..800896 (-) 903 WP_003090206.1 helix-turn-helix transcriptional regulator Regulator
  FY406_RS03945 (FY406_03945) - 801222..803114 (+) 1893 WP_003090205.1 DUF2207 domain-containing protein -
  FY406_RS03950 (FY406_03950) - 803165..804010 (+) 846 WP_003090201.1 undecaprenyl-diphosphate phosphatase -
  FY406_RS03955 (FY406_03955) mecA 804102..804818 (+) 717 WP_003090200.1 adaptor protein MecA Regulator
  FY406_RS03960 (FY406_03960) - 804824..805984 (+) 1161 WP_003090195.1 glycosyltransferase family 4 protein -
  FY406_RS03965 (FY406_03965) sufC 806059..806829 (+) 771 WP_003090193.1 Fe-S cluster assembly ATPase SufC -
  FY406_RS03970 (FY406_03970) sufD 806866..808128 (+) 1263 WP_003090192.1 Fe-S cluster assembly protein SufD -
  FY406_RS03975 (FY406_03975) - 808130..809362 (+) 1233 WP_003090191.1 cysteine desulfurase -
  FY406_RS03980 (FY406_03980) sufU 809349..809792 (+) 444 WP_003090190.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27621.16 Da        Isoelectric Point: 4.1430

>NTDB_id=383560 FY406_RS03955 WP_003090200.1 804102..804818(+) (mecA) [Streptococcus ratti strain ATCC 31377]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFKTLEETMREKGDTAALDKLAEAEKKEEEAQKQNEESEQPDYIHFVLDFPSLKEAVS
FAKTVDYEVEASELFKEADAYHMTILLSLENKPDYYADLMFARMLEHAGKGTKTRAYLLEHGVQLIMSDALQELQMIG

Nucleotide


Download         Length: 717 bp        

>NTDB_id=383560 FY406_RS03955 WP_003090200.1 804102..804818(+) (mecA) [Streptococcus ratti strain ATCC 31377]
ATGGAAATGAAACAAATCAGCGAAACAACACTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAGGATTTCTTAATTCCACAGGAAAAAACAGAAGAATTTTTCTATACTGTTATGGATGAATTAGATCTGCCTGAGAATT
TTAAAGACAGCGGCATGCTGAGCTTTCGCGTCACACCGAGAAATGATCGGATCGATGTTTTTGTGACCAAATCAGAAATC
AACAAGAACCTTAATCTGGAGGACTTGTCTGACTTTGATGATATCTCAAAAATGTCTCCTGAGGATTTCTTCAAAACTTT
GGAAGAGACTATGAGAGAAAAAGGCGATACGGCAGCTTTAGATAAACTGGCTGAAGCAGAGAAAAAGGAAGAGGAAGCCC
AAAAACAAAATGAAGAGAGCGAGCAGCCAGACTATATTCACTTTGTTCTTGATTTTCCAAGCCTAAAAGAAGCGGTCAGC
TTTGCTAAGACGGTTGATTATGAGGTGGAAGCATCAGAACTTTTTAAGGAAGCTGATGCCTATCATATGACGATTCTTCT
CAGCCTTGAAAATAAGCCGGATTATTATGCTGATCTTATGTTTGCCAGAATGTTAGAACACGCTGGCAAAGGGACTAAGA
CACGGGCTTACCTTTTAGAGCACGGCGTTCAGCTGATCATGTCAGATGCTCTGCAAGAATTGCAAATGATTGGATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7X9LCM5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

87.5

100

0.882
  mecA Streptococcus thermophilus LMD-9

58.197

100

0.597
  mecA Streptococcus thermophilus LMG 18311

57.787

100

0.592
  mecA Streptococcus pneumoniae Rx1

51.429

100

0.529
  mecA Streptococcus pneumoniae D39

51.429

100

0.529
  mecA Streptococcus pneumoniae R6

51.429

100

0.529
  mecA Streptococcus pneumoniae TIGR4

51.02

100

0.525

Multiple sequence alignment