Detailed information NTG0383558

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FY406_RS03175
• Genome accession: NZ_CP043405
• Coordinates: 658823..659737 (+)
• Length: 304 a.a.
• NCBI ID: WP_003090542.1
• Uniprot ID: -
• Organism: Streptococcus ratti strain ATCC 31377
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 653823..664737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FY406_RS03145 (FY406_03145)	-	653943..654692 (+)	750	WP_003086944.1	hypothetical protein	-
FY406_RS03150 (FY406_03150)	-	654703..655395 (+)	693	WP_003086943.1	aspartate/glutamate racemase family protein	-
FY406_RS03155 (FY406_03155)	-	655460..656071 (+)	612	WP_003086942.1	CPBP family intramembrane glutamic endopeptidase	-
FY406_RS03160 (FY406_03160)	-	656104..656505 (+)	402	WP_003086941.1	SRPBCC family protein	-
FY406_RS10630	-	656507..656560 (+)	54	WP_162129578.1	hypothetical protein	-
FY406_RS03165 (FY406_03165)	-	656583..657380 (+)	798	WP_225310761.1	hypothetical protein	-
FY406_RS03170 (FY406_03170)	purB	657384..658682 (+)	1299	WP_003086936.1	adenylosuccinate lyase	-
FY406_RS03175 (FY406_03175)	comR	658823..659737 (+)	915	WP_003090542.1	helix-turn-helix domain-containing protein	Regulator
FY406_RS03180 (FY406_03180)	ruvB	660082..661083 (+)	1002	WP_003086929.1	Holliday junction branch migration DNA helicase RuvB	-
FY406_RS03185 (FY406_03185)	-	661114..661536 (+)	423	WP_003086927.1	low molecular weight protein-tyrosine-phosphatase	-
FY406_RS03190 (FY406_03190)	-	661603..661983 (+)	381	WP_003090541.1	hypothetical protein	-
FY406_RS03195 (FY406_03195)	-	661980..663764 (+)	1785	WP_003086923.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 36059.40 Da
• Isoelectric Point: 4.6051

>NTDB_id=383558 FY406_RS03175 WP_003090542.1 658823..659737(+) (comR) [Streptococcus ratti strain ATCC 31377]
MLEDFGERVKRLRLEKGLTKEVFCQDESELSMRQLTRIESGESVPTLRKAVYIAERLGVTLDYLTDGRNIDLPNRYKELK
YLLLRTPTYGDQEKLAEREVYFDEIFNHFYDTLPEEEQLVIDALQSKLDIHLSQNIDFGVGILNDYFDQILMRKRYQVND
LIIIDLYFSCLTISDLRMDIFDLDKYHKLMQVLLKQSDYLPVEDLFVLNNVLLNNFGILLLLEKYDIIKELIAVANDIMV
RTSDFQKKPIVSILEWKYYLLAENNEAEARKSYDSAILFAKLTENTTLREKLEREWQKDYQNRT

Nucleotide

• Length: 915 bp

>NTDB_id=383558 FY406_RS03175 WP_003090542.1 658823..659737(+) (comR) [Streptococcus ratti strain ATCC 31377]
ATGTTAGAAGATTTTGGGGAGAGAGTAAAACGTCTGCGGTTAGAAAAGGGACTGACCAAAGAAGTTTTCTGTCAAGATGA
GTCTGAGCTGTCTATGCGGCAGCTGACAAGGATTGAGTCGGGGGAATCAGTGCCTACGCTCAGAAAGGCTGTTTATATTG
CTGAGCGCTTAGGTGTAACACTGGATTATCTGACGGATGGAAGAAATATTGATCTGCCGAACCGTTACAAGGAACTGAAA
TATCTGTTGCTGAGAACACCGACCTACGGCGATCAGGAAAAGCTGGCTGAAAGGGAGGTTTATTTTGATGAGATTTTTAA
TCATTTTTATGACACCCTGCCTGAGGAAGAGCAGCTTGTGATTGATGCTCTTCAGTCAAAATTAGATATTCATTTGAGCC
AAAATATTGATTTTGGGGTCGGAATTTTAAACGATTACTTTGATCAGATTTTAATGCGCAAACGCTATCAGGTGAATGAT
TTAATCATCATTGATCTTTATTTTTCCTGCCTAACGATCAGTGATTTACGTATGGATATTTTTGATTTGGATAAGTATCA
TAAGCTGATGCAGGTCCTTTTAAAACAGAGTGATTACCTGCCCGTGGAAGATTTATTTGTGCTGAATAACGTTTTATTAA
ATAATTTTGGCATTCTCCTTCTTTTAGAAAAATATGACATTATCAAGGAGCTGATTGCAGTTGCCAATGATATCATGGTA
AGGACCTCTGATTTTCAAAAGAAACCCATTGTCAGTATACTTGAATGGAAGTATTATCTGTTGGCAGAGAATAATGAAGC
AGAAGCAAGAAAAAGCTATGACTCGGCTATTTTGTTTGCGAAATTAACTGAAAATACCACATTAAGAGAAAAGTTAGAAA
GAGAGTGGCAGAAGGACTACCAAAACAGGACATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (9-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	74.013	100	0.74
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	50.347	94.737	0.477
comR	Streptococcus pyogenes MGAS315	45.485	98.355	0.447
comR	Streptococcus pyogenes MGAS8232	44.04	99.342	0.438
comR	Streptococcus suis P1/7	43.813	98.355	0.431
comR	Streptococcus suis 05ZYH33	43.813	98.355	0.431
comR	Streptococcus suis D9	40.532	99.013	0.401