Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   FXN58_RS02850 Genome accession   NZ_CP043003
Coordinates   532086..533441 (-) Length   451 a.a.
NCBI ID   WP_148323785.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain HK_907     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 527086..538441
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FXN58_RS02825 (FXN58_02820) - 527849..528235 (+) 387 WP_392388678.1 Mov34/MPN/PAD-1 family protein -
  FXN58_RS02830 (FXN58_02825) - 528228..529058 (+) 831 WP_148323777.1 DUF6602 domain-containing protein -
  FXN58_RS02835 (FXN58_02830) - 529323..530177 (-) 855 WP_148323779.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  FXN58_RS02840 (FXN58_02835) aroB 530180..531268 (-) 1089 WP_148323781.1 3-dehydroquinate synthase -
  FXN58_RS02845 (FXN58_02840) aroK 531292..531819 (-) 528 WP_148323783.1 shikimate kinase AroK -
  FXN58_RS02850 (FXN58_02845) comE 532086..533441 (-) 1356 WP_148323785.1 type IV pilus secretin PilQ Machinery gene
  FXN58_RS02855 (FXN58_02850) - 533462..533854 (-) 393 WP_148323787.1 pilus assembly protein PilP -
  FXN58_RS02860 (FXN58_02855) - 533854..534378 (-) 525 WP_148323789.1 type II secretion system protein M -
  FXN58_RS02865 (FXN58_02860) - 534375..534893 (-) 519 WP_148323791.1 PilN domain-containing protein -
  FXN58_RS02870 (FXN58_02865) - 534904..535713 (-) 810 WP_148323793.1 competence protein ComA -
  FXN58_RS02875 (FXN58_02870) - 535847..538414 (+) 2568 WP_005581959.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 451 a.a.        Molecular weight: 49305.44 Da        Isoelectric Point: 6.5120

>NTDB_id=380119 FXN58_RS02850 WP_148323785.1 532086..533441(-) (comE) [Aggregatibacter actinomycetemcomitans strain HK_907]
MKSILSRQLKCGLLFGCFLSLAVQAEQNPVFSIRLKQAPLVPTLQQLALAHNTNLIIDDELQGTVSLQLENVDLDQLFRS
VAKIKQLDLWQENGIYYFTKGDTNTKFAGKMEEPFPLSVSMAEEPAQLTTATIKLHFAKASEVMKSLTGGSGSLLSPNGS
ITFDDRSNLLLIQDEPRSVHNIKKLIKELDKPIEQIAIEARIVTINDESLKELGGRWGIFSPTDNAHRVGGSLAGNGFDN
LVNQLNVNFPTTTTPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTELPYILVNEKSGSQ
SVEFREAVLGLEVTPHISQDKQILLDLIVSQNSPGSRVAYGLGEVVSIDKQEINTQVFAKDGETVVLGGVFSDTITKGTD
KVPVLGDIPGIKHLFSKESERHQKRELVIFVTPHILRKGAPRTLSNKSESG

Nucleotide


Download         Length: 1356 bp        

>NTDB_id=380119 FXN58_RS02850 WP_148323785.1 532086..533441(-) (comE) [Aggregatibacter actinomycetemcomitans strain HK_907]
ATGAAATCGATTCTTTCCCGACAGCTAAAGTGCGGTCTGCTTTTCGGGTGTTTTTTAAGTCTTGCGGTGCAGGCGGAACA
AAATCCGGTGTTTTCCATTCGGCTGAAACAGGCACCACTGGTTCCGACTTTGCAGCAGTTGGCATTAGCCCACAATACCA
ATTTGATTATTGACGACGAGCTGCAGGGCACGGTGTCGTTACAGTTGGAAAACGTGGATTTGGATCAGCTGTTTCGTTCT
GTGGCGAAAATTAAACAACTGGATTTATGGCAGGAAAACGGCATTTATTATTTCACTAAAGGCGACACCAACACGAAATT
TGCCGGCAAAATGGAAGAGCCTTTCCCTCTTTCAGTGTCCATGGCGGAAGAACCGGCACAGCTGACCACGGCGACCATTA
AATTACACTTTGCCAAAGCGTCGGAAGTGATGAAATCCCTCACCGGGGGGAGCGGTTCCCTGTTGTCGCCTAACGGCAGT
ATCACTTTCGACGATCGTAGCAATTTGTTGCTGATTCAGGATGAACCGCGTTCCGTCCACAACATAAAAAAGCTGATTAA
GGAACTTGATAAACCCATTGAGCAAATCGCCATTGAAGCGCGCATTGTCACCATTAACGATGAAAGCCTGAAAGAACTGG
GCGGGCGCTGGGGGATCTTCAGCCCGACGGACAACGCCCATCGCGTCGGCGGCAGTTTGGCGGGCAACGGCTTTGATAAT
CTTGTCAATCAGTTAAACGTAAATTTTCCCACGACCACGACACCGGCAGGCTCTGTGGCGTTACAGGTTGCGAAAATCAA
TGGGCGACTTTTAGACTTAGAATTGACCGCACTTGAACGGGAAAATAATGTGGAAATCATCGCAAGCCCACGACTGCTAA
CGACAAACAAAAAAAGCGCCAGCATCAAACAGGGGACGGAATTGCCCTATATTCTGGTGAACGAAAAAAGCGGTTCGCAA
AGCGTAGAATTTCGTGAGGCGGTACTAGGTTTGGAAGTCACGCCGCACATTTCGCAGGATAAACAAATTCTGTTAGATCT
TATCGTCAGCCAAAACTCGCCGGGCAGCCGTGTGGCATACGGTTTGGGCGAAGTGGTTTCTATTGATAAACAGGAGATTA
ATACACAAGTCTTCGCCAAGGACGGCGAAACCGTTGTGCTGGGCGGTGTATTTAGCGATACCATCACCAAAGGCACCGAT
AAAGTGCCGGTGCTGGGTGACATTCCGGGTATTAAACATTTATTCAGCAAGGAAAGTGAACGCCATCAAAAACGCGAGCT
GGTGATTTTTGTCACACCACATATTTTGCGTAAAGGCGCCCCCCGGACGCTTTCAAACAAAAGCGAATCGGGGTAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(130-195)

Bacterial type II and III secretion system protein (Secretin)

(277-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

70.852

98.891

0.701
  comE Haemophilus influenzae 86-028NP

70.805

96.452

0.683
  comE Glaesserella parasuis strain SC1401

52

94.235

0.49
  pilQ Vibrio campbellii strain DS40M4

41.475

96.231

0.399
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.056

94.9

0.399
  pilQ Vibrio cholerae strain A1552

42.056

94.9

0.399

Multiple sequence alignment