Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE/cglE   Type   Machinery gene
Locus tag   HMPREF0837_RS00240 Genome accession   NC_014251
Coordinates   38027..38329 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TCH8431/19A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 33027..43329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0837_RS00210 (HMPREF0837_10038) rnpA 33713..34084 (-) 372 WP_000739246.1 ribonuclease P protein component -
  HMPREF0837_RS13140 (HMPREF0837_10039) - 34101..34232 (-) 132 WP_000768904.1 hypothetical protein -
  HMPREF0837_RS00215 (HMPREF0837_10040) - 34233..35423 (-) 1191 WP_000167766.1 acetate kinase -
  HMPREF0837_RS00220 (HMPREF0837_10041) comYH 35474..36427 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF0837_RS00225 (HMPREF0837_10042) - 36488..37075 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  HMPREF0837_RS00230 (HMPREF0837_10043) comGG/cglG 37212..37625 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  HMPREF0837_RS00235 (HMPREF0837_10044) comGF/cglF 37603..38064 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF0837_RS00240 (HMPREF0837_10045) comGE/cglE 38027..38329 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  HMPREF0837_RS00245 (HMPREF0837_10046) comGD/cglD 38292..38696 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF0837_RS00250 (HMPREF0837_10047) comGC/cglC 38689..39015 (-) 327 WP_000738650.1 comG operon protein ComGC Machinery gene
  HMPREF0837_RS00255 (HMPREF0837_10048) comGB/cglB 39017..40033 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF0837_RS00260 (HMPREF0837_10049) comGA/cglA/cilD 39981..40922 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF0837_RS00265 (HMPREF0837_10050) - 40998..41363 (-) 366 WP_000286415.1 DUF1033 family protein -
  HMPREF0837_RS00270 (HMPREF0837_10051) - 41514..42572 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence


Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=37574 HMPREF0837_RS00240 WP_000413380.1 38027..38329(-) (comGE/cglE) [Streptococcus pneumoniae TCH8431/19A]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=37574 HMPREF0837_RS00240 WP_000413380.1 38027..38329(-) (comGE/cglE) [Streptococcus pneumoniae TCH8431/19A]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99

  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99

  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99

  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99

  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99

  comGE/cglE Streptococcus mitis SK321

98

100

0.98

  comYE Streptococcus mutans UA140

43.333

90

0.39

  comYE Streptococcus mutans UA159

43.333

90

0.39


Multiple sequence alignment