Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   HMPREF0837_RS00220 Genome accession   NC_014251
Coordinates   35474..36427 (-) Length   317 a.a.
NCBI ID   WP_000345119.1    Uniprot ID   A0A0T7TMT7
Organism   Streptococcus pneumoniae TCH8431/19A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 30474..41427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0837_RS00195 (HMPREF0837_10035) - 31235..31858 (-) 624 WP_000932633.1 hypothetical protein -
  HMPREF0837_RS00200 (HMPREF0837_10036) jag 31909..32895 (-) 987 WP_000260019.1 RNA-binding cell elongation regulator Jag/EloR -
  HMPREF0837_RS00205 (HMPREF0837_10037) - 32914..33738 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  HMPREF0837_RS00210 (HMPREF0837_10038) rnpA 33713..34084 (-) 372 WP_000739246.1 ribonuclease P protein component -
  HMPREF0837_RS13140 (HMPREF0837_10039) - 34101..34232 (-) 132 WP_000768904.1 hypothetical protein -
  HMPREF0837_RS00215 (HMPREF0837_10040) - 34233..35423 (-) 1191 WP_000167766.1 acetate kinase -
  HMPREF0837_RS00220 (HMPREF0837_10041) comYH 35474..36427 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF0837_RS00225 (HMPREF0837_10042) - 36488..37075 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  HMPREF0837_RS00230 (HMPREF0837_10043) comGG/cglG 37212..37625 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  HMPREF0837_RS00235 (HMPREF0837_10044) comGF/cglF 37603..38064 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF0837_RS00240 (HMPREF0837_10045) comGE/cglE 38027..38329 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  HMPREF0837_RS00245 (HMPREF0837_10046) comGD/cglD 38292..38696 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF0837_RS00250 (HMPREF0837_10047) comGC/cglC 38689..39015 (-) 327 WP_000738650.1 comG operon protein ComGC Machinery gene
  HMPREF0837_RS00255 (HMPREF0837_10048) comGB/cglB 39017..40033 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF0837_RS00260 (HMPREF0837_10049) comGA/cglA/cilD 39981..40922 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF0837_RS00265 (HMPREF0837_10050) - 40998..41363 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35746.93 Da        Isoelectric Point: 4.2434

>NTDB_id=37571 HMPREF0837_RS00220 WP_000345119.1 35474..36427(-) (comYH) [Streptococcus pneumoniae TCH8431/19A]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=37571 HMPREF0837_RS00220 WP_000345119.1 35474..36427(-) (comYH) [Streptococcus pneumoniae TCH8431/19A]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T7TMT7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.313

98.738

0.536
  comYH Streptococcus mutans UA159

53.994

98.738

0.533

Multiple sequence alignment