Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   HMPREF0837_RS00250 Genome accession   NC_014251
Coordinates   38689..39015 (-) Length   108 a.a.
NCBI ID   WP_000738650.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TCH8431/19A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 33689..44015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0837_RS00210 (HMPREF0837_10038) rnpA 33713..34084 (-) 372 WP_000739246.1 ribonuclease P protein component -
  HMPREF0837_RS13140 (HMPREF0837_10039) - 34101..34232 (-) 132 WP_000768904.1 hypothetical protein -
  HMPREF0837_RS00215 (HMPREF0837_10040) - 34233..35423 (-) 1191 WP_000167766.1 acetate kinase -
  HMPREF0837_RS00220 (HMPREF0837_10041) comYH 35474..36427 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF0837_RS00225 (HMPREF0837_10042) - 36488..37075 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  HMPREF0837_RS00230 (HMPREF0837_10043) comGG/cglG 37212..37625 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  HMPREF0837_RS00235 (HMPREF0837_10044) comGF/cglF 37603..38064 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF0837_RS00240 (HMPREF0837_10045) comGE/cglE 38027..38329 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  HMPREF0837_RS00245 (HMPREF0837_10046) comGD/cglD 38292..38696 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF0837_RS00250 (HMPREF0837_10047) comGC/cglC 38689..39015 (-) 327 WP_000738650.1 comG operon protein ComGC Machinery gene
  HMPREF0837_RS00255 (HMPREF0837_10048) comGB/cglB 39017..40033 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF0837_RS00260 (HMPREF0837_10049) comGA/cglA/cilD 39981..40922 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF0837_RS00265 (HMPREF0837_10050) - 40998..41363 (-) 366 WP_000286415.1 DUF1033 family protein -
  HMPREF0837_RS00270 (HMPREF0837_10051) - 41514..42572 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  HMPREF0837_RS00275 (HMPREF0837_10052) nagA 42735..43886 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12189.35 Da        Isoelectric Point: 10.0523

>NTDB_id=37576 HMPREF0837_RS00250 WP_000738650.1 38689..39015(-) (comGC/cglC) [Streptococcus pneumoniae TCH8431/19A]
MKKMMTFLKKSKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
DGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=37576 HMPREF0837_RS00250 WP_000738650.1 38689..39015(-) (comGC/cglC) [Streptococcus pneumoniae TCH8431/19A]
ATGAAAAAAATGATGACATTCTTGAAAAAATCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae D39

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae R6

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comGC/cglC Streptococcus mitis SK321

93.519

100

0.935
  comGC/cglC Streptococcus mitis NCTC 12261

92.157

94.444

0.87
  comYC Streptococcus gordonii str. Challis substr. CH1

72.917

88.889

0.648
  comYC Streptococcus mutans UA140

63.725

94.444

0.602
  comYC Streptococcus mutans UA159

63.725

94.444

0.602
  comYC Streptococcus suis isolate S10

70.37

75

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comGC Staphylococcus aureus MW2

50

79.63

0.398
  comGC Staphylococcus aureus N315

50

79.63

0.398
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment