Detailed information NTG0037573

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: HMPREF0837_RS00235
• Genome accession: NC_014251
• Coordinates: 37603..38064 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250545.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae TCH8431/19A
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 32603..43064

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0837_RS00205 (HMPREF0837_10037)	-	32914..33738 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
HMPREF0837_RS00210 (HMPREF0837_10038)	rnpA	33713..34084 (-)	372	WP_000739246.1	ribonuclease P protein component	-
HMPREF0837_RS13140 (HMPREF0837_10039)	-	34101..34232 (-)	132	WP_000768904.1	hypothetical protein	-
HMPREF0837_RS00215 (HMPREF0837_10040)	-	34233..35423 (-)	1191	WP_000167766.1	acetate kinase	-
HMPREF0837_RS00220 (HMPREF0837_10041)	comYH	35474..36427 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
HMPREF0837_RS00225 (HMPREF0837_10042)	-	36488..37075 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
HMPREF0837_RS00230 (HMPREF0837_10043)	comGG/cglG	37212..37625 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
HMPREF0837_RS00235 (HMPREF0837_10044)	comGF/cglF	37603..38064 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
HMPREF0837_RS00240 (HMPREF0837_10045)	comGE/cglE	38027..38329 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
HMPREF0837_RS00245 (HMPREF0837_10046)	comGD/cglD	38292..38696 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
HMPREF0837_RS00250 (HMPREF0837_10047)	comGC/cglC	38689..39015 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
HMPREF0837_RS00255 (HMPREF0837_10048)	comGB/cglB	39017..40033 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
HMPREF0837_RS00260 (HMPREF0837_10049)	comGA/cglA/cilD	39981..40922 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
HMPREF0837_RS00265 (HMPREF0837_10050)	-	40998..41363 (-)	366	WP_000286415.1	DUF1033 family protein	-
HMPREF0837_RS00270 (HMPREF0837_10051)	-	41514..42572 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17855.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=37573 HMPREF0837_RS00235 WP_000250545.1 37603..38064(-) (comGF/cglF) [Streptococcus pneumoniae TCH8431/19A]
MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RFYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=37573 HMPREF0837_RS00235 WP_000250545.1 37603..38064(-) (comGF/cglF) [Streptococcus pneumoniae TCH8431/19A]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT
CGTCATCAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTGGAAGGCAAT
CGTTTCTATATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915