Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   G4G26_RS20480 Genome accession   NZ_CP049924
Coordinates   4006837..4008039 (-) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis strain So1b     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4001837..4013039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G4G26_RS20445 (G4G26_20510) - 4002314..4003267 (-) 954 WP_015715049.1 sporulation-delaying protein SdpB family protein -
  G4G26_RS20450 (G4G26_20515) - 4003252..4003806 (-) 555 WP_015715050.1 SdpA family antimicrobial peptide system protein -
  G4G26_RS20455 (G4G26_20520) - 4003990..4004625 (-) 636 WP_041520538.1 SdpI family protein -
  G4G26_RS20460 (G4G26_20525) - 4004625..4004909 (-) 285 WP_015715052.1 autorepressor SdpR family transcription factor -
  G4G26_RS20465 (G4G26_20530) rocR 4005140..4006525 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  G4G26_RS20470 (G4G26_20535) - 4006507..4006665 (-) 159 Protein_4007 ATP-binding protein -
  G4G26_RS20475 (G4G26_20540) - 4006687..4006816 (-) 130 Protein_4008 hypothetical protein -
  G4G26_RS20480 (G4G26_20545) htrA 4006837..4008039 (-) 1203 WP_015250812.1 serine protease HtrC Regulator
  G4G26_RS20485 (G4G26_20550) vicX 4008121..4008915 (-) 795 WP_088467475.1 MBL fold metallo-hydrolase Regulator
  G4G26_RS20490 (G4G26_20555) walI 4008937..4009779 (-) 843 WP_128422530.1 WalRK two-component regulatory system regulator WalI -
  G4G26_RS20495 (G4G26_20560) walH 4009766..4011133 (-) 1368 WP_046664054.1 WalRK two-component regulatory system regulator WalH -
  G4G26_RS20500 (G4G26_20565) walK 4011123..4012958 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=375711 G4G26_RS20480 WP_015250812.1 4006837..4008039(-) (htrA) [Bacillus subtilis strain So1b]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=375711 G4G26_RS20480 WP_015250812.1 4006837..4008039(-) (htrA) [Bacillus subtilis strain So1b]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGTGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACAGGCG
CCTTAGATCAGCAGCAGAACAATAACGGACGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGGGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCGCGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGATCTG
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTCGATGT
CATCACGGAATTTGACGGTTACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378