Detailed information NTG0375234

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: FPT06_RS05270
• Genome accession: NZ_CP041994
• Coordinates: 1034965..1036161 (-)
• Length: 398 a.a.
• NCBI ID: WP_009911075.1
• Uniprot ID: G7SHV4
• Organism: Streptococcus suis strain INT-01
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1029965..1041161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPT06_RS05250 (FPT06_05250)	-	1030161..1031030 (-)	870	WP_013730047.1	diacylglycerol kinase family protein	-
FPT06_RS05255 (FPT06_05255)	dnaN	1031274..1032410 (-)	1137	WP_004194538.1	DNA polymerase III subunit beta	-
FPT06_RS05260 (FPT06_05260)	dnaA	1032564..1033937 (-)	1374	WP_004194536.1	chromosomal replication initiator protein DnaA	-
FPT06_RS05265 (FPT06_05265)	spo0J	1034140..1034904 (-)	765	WP_004194534.1	ParB/RepB/Spo0J family partition protein	Regulator
FPT06_RS05270 (FPT06_05270)	htrA	1034965..1036161 (-)	1197	WP_009911075.1	S1C family serine protease	Regulator
FPT06_RS05275 (FPT06_05275)	rlmH	1036335..1036814 (+)	480	WP_004194528.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
FPT06_RS05280 (FPT06_05280)	-	1036839..1037522 (+)	684	WP_004194526.1	YoaK family protein	-
FPT06_RS05300 (FPT06_05300)	-	1037923..1040502 (-)	2580	WP_004194524.1	YfhO family protein	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41818.83 Da
• Isoelectric Point: 4.6655

>NTDB_id=375234 FPT06_RS05270 WP_009911075.1 1034965..1036161(-) (htrA) [Streptococcus suis strain INT-01]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPRVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=375234 FPT06_RS05270 WP_009911075.1 1034965..1036161(-) (htrA) [Streptococcus suis strain INT-01]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAGCCACGGGTTCAACAAGCAAATTCTGCCATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCTACTACAAAGGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCCGTTGCTGGGGAGGGATCTGGTGTTAT
CTACAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCTGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

3D structure

• AlphaFold DB: G7SHV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.446	99.749	0.593
htrA	Streptococcus gordonii str. Challis substr. CH1	59.494	99.246	0.59
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565