Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   FPL13_RS02660 Genome accession   NZ_CP041968
Coordinates   545210..545911 (+) Length   233 a.a.
NCBI ID   WP_049513494.1    Uniprot ID   A0AAU7Q090
Organism   Streptococcus sp. KS 6     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 540210..550911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS02640 (FPL13_02690) ccpA 540910..541914 (+) 1005 WP_049514346.1 catabolite control protein A Regulator
  FPL13_RS02645 (FPL13_02695) - 542246..543244 (+) 999 WP_049513500.1 glycosyltransferase family 4 protein -
  FPL13_RS02650 (FPL13_02700) - 543246..544559 (+) 1314 WP_049513498.1 glycosyltransferase family 4 protein -
  FPL13_RS02655 (FPL13_02705) - 544585..544926 (+) 342 WP_049513496.1 hypothetical protein -
  FPL13_RS02660 (FPL13_02710) micA 545210..545911 (+) 702 WP_049513494.1 response regulator YycF Regulator
  FPL13_RS02665 (FPL13_02715) micB 545904..547256 (+) 1353 WP_022526267.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FPL13_RS02670 (FPL13_02720) vicX 547258..548061 (+) 804 WP_049513492.1 MBL fold metallo-hydrolase Regulator
  FPL13_RS02675 (FPL13_02725) - 548070..548429 (+) 360 WP_049513490.1 YbaN family protein -
  FPL13_RS02680 (FPL13_02730) rnc 548814..549512 (+) 699 WP_049513488.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26953.92 Da        Isoelectric Point: 4.6947

>NTDB_id=374998 FPL13_RS02660 WP_049513494.1 545210..545911(+) (micA) [Streptococcus sp. KS 6]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAEHPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAEPKEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=374998 FPL13_RS02660 WP_049513494.1 545210..545911(+) (micA) [Streptococcus sp. KS 6]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCGACGGTCGCGAAGCGTTAGAAATGTTTGAAGCAGAACATCCAGATATTTTGATTTTGGACTTGA
TGTTGCCCGAAATGGATGGTTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGACAAAGTTATTGGTCTTGAGATTGGTGCAGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
ATTGCAGGCGCGTGTCAAAGCCATTTTGCGGCGGACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGAACCAAAAG
AAATTGTGATTGGAGATCTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTAGATTTAACACAC
CGTGAGTTTGAATTGCTCCACCATTTGGCAACGCATATCGGGCAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGCTATGATTATTTTGGAGATGTGCGGACGGTCGATGTGACAATTCGTCGTTTGAGAGAAAAGATTGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACACGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

44.978

98.283

0.442
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment