Detailed information NTG0374999

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: FPL13_RS02665
• Genome accession: NZ_CP041968
• Coordinates: 545904..547256 (+)
• Length: 450 a.a.
• NCBI ID: WP_022526267.1
• Uniprot ID: A0A7L8W455
• Organism: Streptococcus sp. KS 6
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 540904..552256

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPL13_RS02640 (FPL13_02690)	ccpA	540910..541914 (+)	1005	WP_049514346.1	catabolite control protein A	Regulator
FPL13_RS02645 (FPL13_02695)	-	542246..543244 (+)	999	WP_049513500.1	glycosyltransferase family 4 protein	-
FPL13_RS02650 (FPL13_02700)	-	543246..544559 (+)	1314	WP_049513498.1	glycosyltransferase family 4 protein	-
FPL13_RS02655 (FPL13_02705)	-	544585..544926 (+)	342	WP_049513496.1	hypothetical protein	-
FPL13_RS02660 (FPL13_02710)	micA	545210..545911 (+)	702	WP_049513494.1	response regulator YycF	Regulator
FPL13_RS02665 (FPL13_02715)	micB	545904..547256 (+)	1353	WP_022526267.1	cell wall metabolism sensor histidine kinase VicK	Regulator
FPL13_RS02670 (FPL13_02720)	vicX	547258..548061 (+)	804	WP_049513492.1	MBL fold metallo-hydrolase	Regulator
FPL13_RS02675 (FPL13_02725)	-	548070..548429 (+)	360	WP_049513490.1	YbaN family protein	-
FPL13_RS02680 (FPL13_02730)	rnc	548814..549512 (+)	699	WP_049513488.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51348.57 Da
• Isoelectric Point: 4.6876

>NTDB_id=374999 FPL13_RS02665 WP_022526267.1 545904..547256(+) (micB) [Streptococcus sp. KS 6]
MIDNIRQFVVSKDFVFVLLILGFILVITLLSLENRRDNVRIRQLNQKVKDLIAGNYSEILDVQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTDTQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide

• Length: 1353 bp

>NTDB_id=374999 FPL13_RS02665 WP_022526267.1 545904..547256(+) (micB) [Streptococcus sp. KS 6]
ATGATTGATAATATTAGACAATTTGTTGTATCAAAAGATTTTGTATTTGTCTTACTCATTTTAGGATTTATTTTGGTGAT
TACCTTGCTTTCCTTGGAAAACCGACGTGATAATGTTCGTATTCGCCAATTGAATCAAAAAGTAAAAGATTTAATTGCAG
GCAATTACTCAGAAATTTTAGATGTACAAGGTGGTCCAGAAATTACGGATATTACCAATAGTATCAATGATTTATCTGAG
GTAATCCGTCTAACGCATGAAAATTTAGAGCAAGAAACTAAGCGCCTGTCAAGTATTTTATCCTATATGACGGACGGTGT
TCTTGCGACCAATCGTCGTGGGCAGATTATTATGATCAATGATATGGCAACCAAACAGTTGGGAGTCAAAGAATCCGAAG
CACGAAAGATGAATATCTTAAAACTGCTGGATATTGAAGACGAATATGACTTACGAGACTTGATTACGAAAGTTCCAGAA
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTTCGATTTGCCTTGATTCGGCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCGGTGTTGCACGATACAACGGAGCAGGAAAAAGAAGAGCGTGAGCGGAGACTGTTTGTTT
CGAATGTCAGTCACGAATTACGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCACTAGATGAAGGTGCCTTGTCA
GAACCAGTTGCACCGGATTTTATCAAGGTTTCATTAGATGAGACCAATCGGATGATGCGAATGGTTTCGGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACAGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGTCAGAACGATGATAAAAAGTATGAAATTATTCGAGATTATCCCATTAATTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAAATTACGGTCAGTATGAAAACAACGGATACCCAAATGATTTTGTCAATTTCAGATGAAGGCTTAGGAATTCCTAAAA
AAGATTTGCCGAAAATTTTTGATAGATTTTATCGTGTAGACAAAGCGAGAAGTCGCGCCCAAGGTGGATCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAGCATAACGGCTTTATCTGGGCAAAGAGCGAGTATGGCAAAGGTTCAACGTT
TACTATAGTTCTGCCGTATGACAAGGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGGTAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-198)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

3D structure

• AlphaFold DB: A0A7L8W455

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	80.638	97.556	0.787
vicK	Streptococcus mutans UA159	71.883	90.889	0.653