Detailed information NTG0373905

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FO444_RS11950
• Genome accession: NZ_CP041759
• Coordinates: 2338692..2339720 (-)
• Length: 342 a.a.
• NCBI ID: WP_017865178.1
• Uniprot ID: A0AAE4T0V0
• Organism: Lactococcus lactis subsp. lactis strain IMAU11823
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2333692..2344720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FO444_RS11920 (FO444_11875)	-	2333979..2334476 (-)	498	WP_003132662.1	nitroreductase family protein	-
FO444_RS11925 (FO444_11880)	-	2334463..2334672 (-)	210	WP_003132661.1	hypothetical protein	-
FO444_RS11930 (FO444_11885)	-	2334669..2335496 (-)	828	WP_026138971.1	radical SAM protein	-
FO444_RS11935	-	2335489..2336688 (-)	1200	WP_017865175.1	MFS transporter	-
FO444_RS11940	-	2336685..2337611 (-)	927	WP_235585823.1	radical SAM protein	-
FO444_RS11945 (FO444_11895)	-	2337714..2338571 (-)	858	WP_058210929.1	Rgg/GadR/MutR family transcriptional regulator	-
FO444_RS11950 (FO444_11900)	sepM	2338692..2339720 (-)	1029	WP_017865178.1	SepM family pheromone-processing serine protease	Regulator
FO444_RS11955 (FO444_11905)	coaD	2339707..2340204 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
FO444_RS11960 (FO444_11910)	rsmD	2340252..2340791 (-)	540	WP_050558566.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FO444_RS11965 (FO444_11915)	-	2340962..2342182 (-)	1221	WP_012898647.1	MFS transporter	-
FO444_RS11970 (FO444_11920)	lmrP	2342266..2343492 (-)	1227	WP_017865180.1	multidrug efflux MFS transporter LmrP	-
FO444_RS11975 (FO444_11925)	-	2343680..2344174 (+)	495	WP_017865181.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37362.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=373905 FO444_RS11950 WP_017865178.1 2338692..2339720(-) (sepM) [Lactococcus lactis subsp. lactis strain IMAU11823]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKNIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=373905 FO444_RS11950 WP_017865178.1 2338692..2339720(-) (sepM) [Lactococcus lactis subsp. lactis strain IMAU11823]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TTAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAAATATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

• PDZ domain (PDZ_2) (134-194)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.986	100	0.494