Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   G6536_RS21945 Genome accession   NZ_CP049330
Coordinates   4273867..4275078 (-) Length   403 a.a.
NCBI ID   WP_017475028.1    Uniprot ID   -
Organism   Bacillus licheniformis strain CP6     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4268867..4280078
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G6536_RS21915 (G6536_22195) rlmH 4269619..4270098 (-) 480 WP_207185258.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  G6536_RS21920 (G6536_22200) - 4270179..4270337 (-) 159 WP_003177948.1 CxxH/CxxC protein -
  G6536_RS21925 (G6536_22205) - 4270536..4271018 (-) 483 WP_009330015.1 DUF4234 domain-containing protein -
  G6536_RS21930 (G6536_22210) - 4271449..4271967 (-) 519 WP_011201784.1 GNAT family N-acetyltransferase -
  G6536_RS21935 (G6536_22215) - 4271998..4272468 (-) 471 WP_009330017.1 membrane protein -
  G6536_RS21940 (G6536_22220) - 4272725..4273570 (-) 846 WP_011198491.1 S-adenosyl-l-methionine hydroxide adenosyltransferase family protein -
  G6536_RS21945 (G6536_22225) htrA 4273867..4275078 (-) 1212 WP_017475028.1 trypsin-like peptidase domain-containing protein Regulator
  G6536_RS21950 (G6536_22230) vicX 4275161..4275955 (-) 795 WP_003177960.1 MBL fold metallo-hydrolase Regulator
  G6536_RS21955 (G6536_22235) yycI 4275970..4276818 (-) 849 WP_003177962.1 two-component system regulatory protein YycI -
  G6536_RS21960 (G6536_22240) yycH 4276805..4278169 (-) 1365 WP_003177963.1 two-component system activity regulator YycH -
  G6536_RS21965 (G6536_22245) walK 4278159..4280003 (-) 1845 WP_003177965.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 403 a.a.        Molecular weight: 43105.93 Da        Isoelectric Point: 5.7694

>NTDB_id=373641 G6536_RS21945 WP_017475028.1 4273867..4275078(-) (htrA) [Bacillus licheniformis strain CP6]
MEFNHDEEKFVREKPVRSWRSFLFSSLVGAVIGALLTLFALPYLSQQGWLPYNLQVIEARGGQGAQQGGTVRNVSVNVNN
EVTQVVSKVSDSVVGVINIQKTGVWDGDSEAGTGSGVIYKKDGNTSHIVTNHHVIEGASQIEISLNDGTRIPAKLIGSDK
LMDLAVLQVNSNKIKAAAEFGDSDKVKTGEPVIAIGNPLGLQFSGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDA
AINPGNSGGGLFNIDGKVIGINSMKIAESAVEGIGLSIPANLAIPVIEDLETYGEVRRPYLGIEMKSLGDIASYHWQETL
KLPKNVTSGVVVMGVQPVSPAGRAGLKELDVIVEFNGDRVYDIVDLRKKLYTKNVGDKVKIKYLRGGKEKTTEVKLTRSQ
LGS

Nucleotide


Download         Length: 1212 bp        

>NTDB_id=373641 G6536_RS21945 WP_017475028.1 4273867..4275078(-) (htrA) [Bacillus licheniformis strain CP6]
GTGGAGTTTAATCATGATGAGGAAAAATTCGTTCGGGAAAAGCCGGTGAGAAGTTGGAGAAGCTTTTTGTTTTCAAGCCT
GGTCGGCGCCGTCATCGGCGCTCTTTTAACATTGTTTGCCTTGCCGTATCTCTCGCAGCAGGGATGGCTGCCGTATAATC
TGCAAGTCATCGAAGCGCGCGGCGGCCAAGGAGCACAGCAGGGCGGGACGGTCCGCAATGTATCCGTCAACGTGAATAAT
GAAGTCACGCAAGTGGTCTCTAAGGTTTCTGATTCTGTTGTCGGCGTTATCAACATCCAAAAGACAGGTGTATGGGATGG
TGACAGCGAAGCGGGAACAGGCTCGGGCGTTATTTATAAAAAGGACGGCAACACATCCCACATTGTGACAAACCACCATG
TCATTGAAGGGGCGTCCCAAATAGAAATCAGCCTGAATGACGGAACACGGATTCCGGCAAAACTGATCGGCAGCGATAAG
CTGATGGATCTGGCCGTCCTGCAAGTCAACAGCAACAAAATAAAAGCAGCTGCCGAATTTGGAGATTCTGATAAAGTGAA
GACAGGCGAGCCTGTCATCGCGATTGGAAACCCGCTCGGCCTGCAGTTTTCAGGCTCTGTTACACAAGGAATCATCTCAG
GAACCGAACGCGCTGTGCCGGTCGATTCCAACGGAGACGGACAGCCGGACTGGAACGCCGAAGTACTGCAGACGGATGCT
GCCATTAACCCGGGTAACAGCGGAGGCGGGCTGTTTAATATTGATGGAAAAGTCATCGGCATTAATTCGATGAAAATCGC
TGAATCAGCCGTCGAAGGCATCGGTCTGAGCATTCCGGCCAACCTTGCCATTCCGGTTATCGAAGATTTGGAAACGTACG
GTGAAGTGAGACGGCCGTATCTCGGAATTGAGATGAAATCACTTGGCGATATCGCAAGCTACCACTGGCAGGAAACGCTT
AAACTGCCGAAAAACGTAACATCAGGCGTAGTTGTGATGGGTGTTCAGCCGGTATCTCCTGCAGGCAGAGCCGGTCTGAA
AGAGCTCGATGTCATCGTCGAATTTAACGGTGACCGTGTTTACGATATCGTTGATCTGCGTAAAAAGCTTTACACCAAAA
ACGTCGGCGACAAGGTAAAAATCAAATACCTGCGGGGCGGAAAAGAAAAGACAACAGAAGTAAAGCTGACCCGATCCCAA
TTAGGAAGCTGA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(299-396)

Peptidase family M50 (Peptidase_M50)

(261-398)

Trypsin-like peptidase domain (Trypsin_2)

(114-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

43.536

94.045

0.409
  htrA Streptococcus mutans UA159

45.17

87.345

0.395
  htrA Streptococcus pneumoniae D39

46.847

82.63

0.387
  htrA Streptococcus pneumoniae TIGR4

46.847

82.63

0.387
  htrA Streptococcus pneumoniae R6

46.847

82.63

0.387
  htrA Streptococcus pneumoniae Rx1

46.847

82.63

0.387
  htrA Streptococcus gordonii str. Challis substr. CH1

42.693

86.6

0.37