Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   FOD75_RS10545 Genome accession   NZ_CP041676
Coordinates   2179497..2179796 (+) Length   99 a.a.
NCBI ID   WP_020843448.1    Uniprot ID   S5N8C6
Organism   Limosilactobacillus reuteri strain LL7     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2174497..2184796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOD75_RS12035 - 2174826..2175080 (+) 255 WP_231122868.1 DUF3278 domain-containing protein -
  FOD75_RS10525 (FOD75_10525) - 2175799..2176860 (+) 1062 WP_144227696.1 GHKL domain-containing protein -
  FOD75_RS10530 (FOD75_10530) - 2176873..2177676 (+) 804 WP_144227699.1 LytR/AlgR family response regulator transcription factor -
  FOD75_RS10535 (FOD75_10535) - 2177748..2178914 (-) 1167 WP_144227704.1 RNA-guided endonuclease TnpB family protein -
  FOD75_RS10540 (FOD75_10540) tnpA 2178936..2179364 (-) 429 WP_144227774.1 IS200/IS605 family transposase -
  FOD75_RS10545 (FOD75_10545) comA 2179497..2179796 (+) 300 WP_020843448.1 cysteine peptidase family C39 domain-containing protein Regulator
  FOD75_RS10550 (FOD75_10550) - 2180058..2180384 (-) 327 WP_019253437.1 type II toxin-antitoxin system PemK/MazF family toxin -
  FOD75_RS10555 (FOD75_10555) - 2180374..2180634 (-) 261 WP_225420498.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  FOD75_RS10560 (FOD75_10560) - 2180878..2181372 (+) 495 WP_102816243.1 prolyl-tRNA synthetase associated domain-containing protein -
  FOD75_RS10565 (FOD75_10565) arsC 2181733..2182143 (+) 411 WP_135951263.1 arsenate reductase (thioredoxin) -
  FOD75_RS10570 (FOD75_10570) - 2182213..2183232 (-) 1020 WP_135951261.1 serine hydrolase domain-containing protein -
  FOD75_RS10575 (FOD75_10575) hpt 2183446..2183982 (+) 537 WP_065533464.1 hypoxanthine phosphoribosyltransferase -
  FOD75_RS10580 (FOD75_10580) - 2184113..2184790 (+) 678 WP_172616833.1 MgtC/SapB family protein -

Sequence

Protein


Download         Length: 99 a.a.        Molecular weight: 11046.78 Da        Isoelectric Point: 8.8454

>NTDB_id=372975 FOD75_RS10545 WP_020843448.1 2179497..2179796(+) (comA) [Limosilactobacillus reuteri strain LL7]
MYNFRRHYINQVDEADCGVAALAMILHNYGSKISLATLRKFTKTTTDGTTALGIVKAAKKLKMDVEAYQADASLFDSKDV
IYPFIADPDIQVKRIPSVF

Nucleotide


Download         Length: 300 bp        

>NTDB_id=372975 FOD75_RS10545 WP_020843448.1 2179497..2179796(+) (comA) [Limosilactobacillus reuteri strain LL7]
ATGTATAACTTTAGAAGACACTATATAAATCAAGTGGATGAAGCTGATTGTGGAGTAGCAGCACTAGCAATGATTCTTCA
TAATTACGGCTCTAAAATTTCATTAGCAACTCTGCGAAAATTTACAAAAACCACTACTGATGGAACTACTGCACTTGGGA
TTGTAAAAGCAGCAAAAAAGTTAAAAATGGATGTTGAAGCATATCAAGCAGATGCTAGTTTATTTGATTCAAAAGATGTA
ATTTATCCTTTTATTGCTGATCCTGATATACAAGTTAAACGTATTCCTTCAGTATTTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(6-86)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S5N8C6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

62.195

82.828

0.515
  comA Streptococcus mitis SK321

54.878

82.828

0.455
  comA Streptococcus mitis NCTC 12261

54.878

82.828

0.455
  comA Streptococcus pneumoniae Rx1

53.659

82.828

0.444
  comA Streptococcus pneumoniae D39

53.659

82.828

0.444
  comA Streptococcus pneumoniae R6

53.659

82.828

0.444
  comA Streptococcus pneumoniae TIGR4

53.659

82.828

0.444
  comA/nlmT Streptococcus mutans UA159

52.381

84.848

0.444

Multiple sequence alignment