Detailed information NTG0368795

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FIU19_RS12985
• Genome accession: NZ_CP041010
• Coordinates: 2428606..2429493 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_766
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2423606..2434493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIU19_RS12950 (FIU19_12945)	-	2423625..2423717 (+)	93	WP_010956583.1	hypothetical protein	-
FIU19_RS12955 (FIU19_12950)	-	2423825..2424322 (-)	498	WP_001065268.1	glutathione peroxidase	-
FIU19_RS12960 (FIU19_12955)	-	2424332..2424592 (-)	261	WP_001789910.1	hypothetical protein	-
FIU19_RS12970 (FIU19_12965)	-	2424974..2425087 (-)	114	WP_011447078.1	hypothetical protein	-
FIU19_RS12975 (FIU19_12970)	-	2425746..2427746 (-)	2001	WP_000776751.1	ABC transporter permease	-
FIU19_RS12980 (FIU19_12975)	-	2427743..2428498 (-)	756	WP_033841467.1	ABC transporter ATP-binding protein	-
FIU19_RS12985 (FIU19_12980)	braS	2428606..2429493 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FIU19_RS12990 (FIU19_12985)	braR	2429504..2430169 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FIU19_RS12995 (FIU19_12990)	-	2430195..2430395 (-)	201	WP_000604728.1	hypothetical protein	-
FIU19_RS13000 (FIU19_12995)	-	2430593..2432017 (+)	1425	WP_000953744.1	alkaline phosphatase	-
FIU19_RS15880 (FIU19_13000)	-	2432077..2432178 (-)	102	WP_000731972.1	SE2200 family small protein	-
FIU19_RS13010 (FIU19_13005)	-	2432300..2432755 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FIU19_RS13015 (FIU19_13010)	-	2433000..2433761 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=368795 FIU19_RS12985 WP_000143419.1 2428606..2429493(-) (braS) [Staphylococcus aureus strain FDAARGOS_766]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=368795 FIU19_RS12985 WP_000143419.1 2428606..2429493(-) (braS) [Staphylococcus aureus strain FDAARGOS_766]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997