Detailed information NTG0368612

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: FIU13_RS06150
• Genome accession: NZ_CP040997
• Coordinates: 1164922..1165356 (+)
• Length: 144 a.a.
• NCBI ID: WP_010921800.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain FDAARGOS_774
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1159922..1170356

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIU13_RS06120 (FIU13_06120)	-	1161591..1161956 (+)	366	WP_002986560.1	DUF1033 family protein	-
FIU13_RS06125 (FIU13_06125)	comYA	1162049..1162987 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
FIU13_RS06130 (FIU13_06130)	comYB	1162923..1163957 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
FIU13_RS06135 (FIU13_06135)	comYC	1163959..1164285 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
FIU13_RS06140 (FIU13_06140)	comGD	1164260..1164688 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
FIU13_RS06145 (FIU13_06145)	comGE	1164645..1164929 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
FIU13_RS06150 (FIU13_06150)	comYF	1164922..1165356 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
FIU13_RS06155 (FIU13_06155)	comGG	1165340..1165666 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
FIU13_RS06160 (FIU13_06160)	comYH	1165764..1166717 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
FIU13_RS06165 (FIU13_06165)	-	1166776..1167972 (+)	1197	WP_010921803.1	acetate kinase	-
FIU13_RS06170 (FIU13_06170)	-	1168159..1168467 (+)	309	WP_010921804.1	hypothetical protein	-
FIU13_RS06175 (FIU13_06175)	proC	1168550..1169320 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16654.28 Da
• Isoelectric Point: 10.2526

>NTDB_id=368612 FIU13_RS06150 WP_010921800.1 1164922..1165356(+) (comYF) [Streptococcus pyogenes strain FDAARGOS_774]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=368612 FIU13_RS06150 WP_010921800.1 1164922..1165356(+) (comYF) [Streptococcus pyogenes strain FDAARGOS_774]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGGTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.445	95.139	0.451
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae D39	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae R6	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae TIGR4	42.857	92.361	0.396
comGF/cglF	Streptococcus mitis SK321	42.105	92.361	0.389