Detailed information NTG0368579

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: FIU13_RS00545
• Genome accession: NZ_CP040997
• Coordinates: 96640..97476 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain FDAARGOS_774
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 91640..102476

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIU13_RS00515 (FIU13_00515)	-	92194..92562 (+)	369	WP_010922310.1	hypothetical protein	-
FIU13_RS00520 (FIU13_00520)	-	92612..93523 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
FIU13_RS00525 (FIU13_00525)	trhA	93640..94290 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
FIU13_RS00530 (FIU13_00530)	-	94287..94727 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
FIU13_RS00535 (FIU13_00535)	ylqF	94946..95794 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
FIU13_RS00540 (FIU13_00540)	-	95784..96575 (+)	792	WP_011285534.1	ribonuclease HII	-
FIU13_RS00545 (FIU13_00545)	dprA	96640..97476 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
FIU13_RS00550 (FIU13_00550)	topA	97583..99712 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
FIU13_RS10085	-	99787..100669 (-)	883	Protein_105	LysR family transcriptional regulator	-
FIU13_RS00565 (FIU13_00565)	-	100682..101227 (+)	546	Protein_106	PTS sugar transporter subunit IIC	-
FIU13_RS00570 (FIU13_00570)	-	101242..102234 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=368579 FIU13_RS00545 WP_010922314.1 96640..97476(+) (dprA) [Streptococcus pyogenes strain FDAARGOS_774]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=368579 FIU13_RS00545 WP_010922314.1 96640..97476(+) (dprA) [Streptococcus pyogenes strain FDAARGOS_774]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367