Detailed information NTG0036613

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SMUNN2025_RS08605
• Genome accession: NC_013928
• Coordinates: 1780438..1782720 (-)
• Length: 760 a.a.
• NCBI ID: WP_002277918.1
• Uniprot ID: -
• Organism: Streptococcus mutans NN2025
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1775438..1787720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNN2025_RS08590 (SmuNN2025_1677)	ulaG	1775805..1776896 (-)	1092	WP_002263526.1	L-ascorbate 6-phosphate lactonase	-
SMUNN2025_RS08595 (SmuNN2025_1678)	-	1777476..1779140 (-)	1665	WP_012997940.1	BglG family transcription antiterminator	-
SMUNN2025_RS08600 (SmuNN2025_1679)	comB/nlmE	1779513..1780424 (-)	912	WP_002269618.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
SMUNN2025_RS08605 (SmuNN2025_1680)	comA/nlmT	1780438..1782720 (-)	2283	WP_002277918.1	peptide cleavage/export ABC transporter	Regulator
SMUNN2025_RS08610 (SmuNN2025_1682)	-	1783375..1783779 (-)	405	WP_002269821.1	hypothetical protein	-
SMUNN2025_RS08615 (SmuNN2025_1683)	-	1783798..1784016 (-)	219	WP_002278140.1	Blp family class II bacteriocin	-
SMUNN2025_RS10495	-	1784296..1784487 (-)	192	WP_162465514.1	hypothetical protein	-
SMUNN2025_RS08620 (SmuNN2025_1685)	-	1785095..1785373 (-)	279	WP_002278151.1	hypothetical protein	-
SMUNN2025_RS08625 (SmuNN2025_1686)	-	1785611..1785820 (-)	210	WP_002273561.1	hypothetical protein	-
SMUNN2025_RS10195 (SmuNN2025_1687)	-	1786303..1786464 (-)	162	WP_162137516.1	hypothetical protein	-
SMUNN2025_RS10565	-	1786505..1786681 (-)	177	WP_079993450.1	hypothetical protein	-
SMUNN2025_RS08630 (SmuNN2025_1688)	-	1786678..1786953 (-)	276	WP_002278146.1	hypothetical protein	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 85094.76 Da
• Isoelectric Point: 8.9095

>NTDB_id=36613 SMUNN2025_RS08605 WP_002277918.1 1780438..1782720(-) (comA/nlmT) [Streptococcus mutans NN2025]
MKQVIYVVLIVIAVNILLEVIKRVTKRGGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIA
YLRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPS
VKVTRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEY
IPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPISFFATRRTGEITSRFTDANQII
DAVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMET
IKSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSN
PIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLV
GASGSGKTTLTKLIVNFYEPNKGIVRINGNDLKVIDKTALRRHISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACE
IAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILTEKKIISNLLQMTEKTIIFVAH
RLSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2283 bp

>NTDB_id=36613 SMUNN2025_RS08605 WP_002277918.1 1780438..1782720(-) (comA/nlmT) [Streptococcus mutans NN2025]
ATGAAACAAGTTATTTATGTTGTTTTAATCGTCATAGCCGTTAACATTCTCTTAGAGGTTATCAAAAGAGTAACAAAAAG
GGGAGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTAGTAC
CTCAGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTACGGATCTAACTACTCTATCGCT
TATCTGCGGGAACTCTCAAAGACTAACAAGCAGGGAACAACAGCTCTTGGCATTGTTGAAGCTGCTAAAAAGTTAGGCTT
TGAAACACGCTCTATCAAGGCGGATATGACGCTTTTTGATTATAATGATTTGACCTATCCTTTTATCGTCCATGTGATTA
AAGGAAAACGTCTGCAGCATTATTATGTCGTCTATGGCAGCCAGAATAATCAGCTGATTATTGGAGATCCTGATCCTTCA
GTTAAGGTGACTAGGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGCCTTGCAATTTTCCTAGCTCCTCAGCCTAA
CTATAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCTAATTTCTTCCCGTTGATCTTTAAGCAGAAAGCTTTGATGACTT
ATATTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTAC
ATTCCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGGTCATGGC
TTTTGCAAAAGAATACCTCTTGGCCGTACTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATCAAACATATTT
TTACGCTTCCTATATCTTTCTTTGCGACAAGGCGAACAGGAGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATT
GATGCTGTAGCGTCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTAATTTTGGTTGGCGGGGTTTTGTTGGCGCA
AAACAATAACCTTTTCTTTCTAACCTTGCTCTCCATTCCGATTTATGCCATCATTATTTTTGCTTTCTTGAAACCCTTTG
AGAAAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGATATCAATGGGATGGAAACC
ATTAAATCACTCACAAGTGAGTCCGCTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAA
GCTACACAAGTATAGTGCCATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATCCTCAATGTTGTCATTCTCTGGTATG
GCTCTCGTCTAGTTATGGATAATAAAATCTCAGTTGGTCAGCTTATCACCTTTAATGCTTTGCTGTCTTATTTCTCAAAT
CCAATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAGGTCTATCT
TGTCGAATCTGAATTTGAAAAAGACGGCGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAAAATCTTT
CTTATAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGTCTAGTT
GGAGCCAGTGGTTCTGGTAAGACAACTTTGACTAAACTGATTGTCAATTTCTACGAGCCTAACAAGGGGATTGTTCGAAT
CAATGGCAATGATTTAAAAGTTATTGATAAGACAGCTTTGCGGCGGCATATTAGCTATTTGCCGCAACAGGCCTATGTTT
TTAGTGGCTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCTTGTGAA
ATTGCTGAAATCCGCTCGGACATTGAACAAATGCCTCAGGGCTATCAGACAGAGTTATCAGATGGTGCCGGTATTTCTGG
CGGTCAAAAACAGCGGATTGCTTTAGCTAGGGCCTTATTAACGCAGGCACCGGTTTTGATTCTGGATGAAGCCACCAGCA
GTCTTGATATTTTGACAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACAATAATTTTTGTTGCCCAC
CGCTTAAGCATTTCACAGCGTACTGACGAAGTCATTGTTATGGATCAGGGAAAAATTGTTGAACAAGGCACTCATAAGGA
ACTTTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (544-693)

• Peptidase C39 family (Peptidase_C39) (50-186)

• ABC transporter transmembrane region (ABC_membrane) (212-481)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	99.605	100	0.996
comA	Streptococcus mitis NCTC 12261	65.132	94.342	0.614
comA	Streptococcus pneumoniae Rx1	64.575	94.342	0.609
comA	Streptococcus pneumoniae D39	64.575	94.342	0.609
comA	Streptococcus pneumoniae R6	64.575	94.342	0.609
comA	Streptococcus mitis SK321	64.435	94.342	0.608
comA	Streptococcus pneumoniae TIGR4	64.296	94.342	0.607
comA	Streptococcus gordonii str. Challis substr. CH1	64.156	94.342	0.605