Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB/nlmE   Type   Regulator
Locus tag   SMUNN2025_RS08600 Genome accession   NC_013928
Coordinates   1779513..1780424 (-) Length   303 a.a.
NCBI ID   WP_002269618.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1774513..1785424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS08590 (SmuNN2025_1677) ulaG 1775805..1776896 (-) 1092 WP_002263526.1 L-ascorbate 6-phosphate lactonase -
  SMUNN2025_RS08595 (SmuNN2025_1678) - 1777476..1779140 (-) 1665 WP_012997940.1 BglG family transcription antiterminator -
  SMUNN2025_RS08600 (SmuNN2025_1679) comB/nlmE 1779513..1780424 (-) 912 WP_002269618.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  SMUNN2025_RS08605 (SmuNN2025_1680) comA/nlmT 1780438..1782720 (-) 2283 WP_002277918.1 peptide cleavage/export ABC transporter Regulator
  SMUNN2025_RS08610 (SmuNN2025_1682) - 1783375..1783779 (-) 405 WP_002269821.1 hypothetical protein -
  SMUNN2025_RS08615 (SmuNN2025_1683) - 1783798..1784016 (-) 219 WP_002278140.1 Blp family class II bacteriocin -
  SMUNN2025_RS10495 - 1784296..1784487 (-) 192 WP_162465514.1 hypothetical protein -
  SMUNN2025_RS08620 (SmuNN2025_1685) - 1785095..1785373 (-) 279 WP_002278151.1 hypothetical protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 34515.00 Da        Isoelectric Point: 10.4914

>NTDB_id=36612 SMUNN2025_RS08600 WP_002269618.1 1779513..1780424(-) (comB/nlmE) [Streptococcus mutans NN2025]
MDPKFLQSAEFYRRRYHNFATLLIVPLVCLIIFLVIFLCFAKKEITVISTGEVAPTKVVDVIQSYSDSSIIKNNLDNNAA
VEKGDVLIEYSENASPNRQTEQKNIIKERQKREEKEKKKHRKSKKKKKSKSKKASKDKKKKSKNKKDKESSSDDENETKK
VSIFASEDGIIHTNPKYDGANIIPKQTEIAQIYPDIQKTRKVLITYYASSDDVVSMKKGQTARLSLEKKGNDKVVIEGKI
NNVASSATTTKKGNLFKVTAKVKVSKKNSKLIKYGMTGKTVTVIDKKTYFDYFKDKLLHKMDN

Nucleotide


Download         Length: 912 bp        

>NTDB_id=36612 SMUNN2025_RS08600 WP_002269618.1 1779513..1780424(-) (comB/nlmE) [Streptococcus mutans NN2025]
ATGGATCCTAAATTTTTACAAAGTGCAGAATTTTATAGGAGACGCTATCATAATTTTGCGACACTATTAATTGTTCCTTT
GGTCTGCTTGATTATCTTTTTGGTTATATTCCTTTGTTTTGCTAAAAAAGAAATTACAGTGATTTCTACTGGTGAAGTTG
CGCCAACAAAGGTTGTAGATGTTATCCAATCTTACAGTGACAGTTCAATCATTAAAAATAATTTAGATAATAATGCAGCT
GTTGAGAAAGGAGACGTTTTAATTGAATATTCAGAAAATGCCAGTCCAAACCGTCAGACTGAACAAAAGAATATTATAAA
AGAAAGACAAAAACGAGAAGAGAAGGAAAAGAAAAAACACCGAAAGAGCAAGAAAAAGAAGAAGTCTAAGAGCAAGAAAG
CTTCCAAAGATAAGAAAAAGAAATCGAAAAACAAGAAAGACAAGGAAAGCAGCTCTGACGATGAAAATGAGACAAAAAAG
GTTTCGATTTTTGCTTCAGAAGATGGTATTATTCATACCAATCCCAAATATGATGGTGCCAATATTATTCCGAAGCAAAC
CGAGATTGCTCAAATCTATCCTGATATTCAAAAAACAAGAAAAGTGTTAATCACCTATTATGCTTCTTCTGATGATGTTG
TTTCTATGAAAAAGGGGCAAACCGCTCGTCTTTCCTTGGAAAAAAAGGGAAATGACAAGGTTGTTATTGAAGGAAAAATT
AACAATGTCGCTTCATCAGCAACTACTACTAAAAAAGGAAATCTCTTTAAGGTTACTGCCAAAGTAAAGGTTTCTAAGAA
AAATAGCAAACTCATCAAGTATGGTATGACAGGCAAGACAGTCACTGTCATTGATAAAAAGACTTATTTTGATTATTTCA
AAGATAAATTACTGCATAAAATGGATAATTAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(163-275)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB/nlmE Streptococcus mutans UA159

98.68

100

0.987

Multiple sequence alignment