Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   SMI_RS10370 Genome accession   NC_013853
Coordinates   2113692..2114354 (-) Length   220 a.a.
NCBI ID   WP_000649962.1    Uniprot ID   D3HBP3
Organism   Streptococcus mitis B6     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2108692..2119354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS10345 (smi_2052) - 2108842..2109108 (-) 267 WP_001278169.1 Veg family protein -
  SMI_RS10350 (smi_2053) dnaB 2109110..2110462 (-) 1353 WP_000852497.1 replicative DNA helicase -
  SMI_RS10355 (smi_2054) rplI 2110506..2110958 (-) 453 WP_000864219.1 50S ribosomal protein L9 -
  SMI_RS10360 (smi_2055) - 2110955..2112928 (-) 1974 WP_000715137.1 DHH family phosphoesterase -
  SMI_RS10365 (smi_2056) hpf 2113064..2113612 (-) 549 WP_000599100.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SMI_RS10370 (smi_2057) comFC/cflB 2113692..2114354 (-) 663 WP_000649962.1 ComF family protein Machinery gene
  SMI_RS10375 (smi_2058) comFA/cflA 2114351..2115649 (-) 1299 WP_000867723.1 DEAD/DEAH box helicase Machinery gene
  SMI_RS10380 (smi_2059) - 2115706..2116341 (+) 636 WP_000395727.1 YigZ family protein -
  SMI_RS10890 - 2116435..2116530 (+) 96 Protein_2029 PH domain-containing protein -
  SMI_RS10385 (smi_2060) cysK 2116627..2117553 (+) 927 WP_000029885.1 cysteine synthase A -
  SMI_RS10390 (smi_2061) tsf 2117675..2118715 (-) 1041 WP_000808070.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25289.35 Da        Isoelectric Point: 7.7114

>NTDB_id=36348 SMI_RS10370 WP_000649962.1 2113692..2114354(-) (comFC/cflB) [Streptococcus mitis B6]
MKCLLCGQTMKTILTFSSLLLLKNDDSCLCSDCDSTFKRIGEEYCPNCMKTGLLTKCQDCQFWCKEGVEVSHRAIFVYNQ
AMKDFFSRYKFDGDFLLRKVFASVLSEELKKYKEYQFVVIPLSPERLLERGFNQVEGLVEVAGFSFQDLLDKREERASYS
KSRSERLATELSFFIKSGVTIPKKILLIDDIYTTGTTINRVKKLLEEAGAEDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=36348 SMI_RS10370 WP_000649962.1 2113692..2114354(-) (comFC/cflB) [Streptococcus mitis B6]
ATGAAGTGCTTGTTGTGTGGGCAGACTATGAAGACTATTTTAACTTTTAGTAGTCTCTTACTTCTGAAGAATGATGACTC
TTGTCTTTGTTCAGACTGTGACTCTACTTTTAAGAGGATTGGAGAAGAGTACTGTCCAAACTGTATGAAAACAGGTTTGT
TAACGAAGTGTCAAGACTGTCAATTTTGGTGTAAAGAAGGAGTTGAGGTGAGTCATAGAGCGATTTTTGTTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTTTTAAGAAAAGTTTTTGCTTCAGTTTTAAGTGA
GGAGTTAAAAAAGTACAAAGAGTATCAATTTGTCGTAATTCCCCTAAGTCCTGAAAGATTGCTCGAGAGGGGATTTAACC
AGGTTGAAGGTTTAGTTGAAGTAGCAGGGTTCTCTTTTCAAGACTTACTGGATAAGAGAGAAGAGAGAGCTAGTTATTCT
AAAAGTCGTTCAGAACGCTTGGCAACAGAACTTTCTTTCTTTATTAAAAGTGGAGTTACTATTCCTAAAAAAATCTTACT
TATAGACGACATTTATACTACTGGAACAACTATAAATCGTGTGAAGAAACTATTGGAAGAGGCTGGTGCTGAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(160-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3HBP3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909
  comFC/cflB Streptococcus mitis NCTC 12261

90.909

100

0.909
  comFC/cflB Streptococcus pneumoniae TIGR4

89.091

100

0.891
  comFC/cflB Streptococcus pneumoniae Rx1

88.636

100

0.886
  comFC/cflB Streptococcus pneumoniae D39

88.636

100

0.886
  comFC/cflB Streptococcus pneumoniae R6

88.636

100

0.886
  comFC Bacillus subtilis subsp. subtilis str. 168

35.526

100

0.368

Multiple sequence alignment