Detailed information
Bioinformatically predicted
Overview
| Name | comFC/cflB | Type | Machinery gene |
| Locus tag | FD735_RS09630 | Genome accession | NZ_CP040231 |
| Coordinates | 1865362..1866024 (-) | Length | 220 a.a. |
| NCBI ID | WP_139659068.1 | Uniprot ID | - |
| Organism | Streptococcus sp. 1643 | ||
| Function | ssDNA transport into the cell (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1828278..1883933 | 1865362..1866024 | within | 0 |
Gene organization within MGE regions
Location: 1828278..1883933
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FD735_RS09435 (FD735_09435) | pnuC | 1828278..1829057 (-) | 780 | WP_139659051.1 | nicotinamide riboside transporter PnuC | - |
| FD735_RS09440 (FD735_09440) | - | 1829067..1830125 (-) | 1059 | WP_139659052.1 | AAA family ATPase | - |
| FD735_RS09445 (FD735_09445) | clpC | 1830271..1832703 (-) | 2433 | WP_139659053.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| FD735_RS09450 (FD735_09450) | - | 1832705..1833163 (-) | 459 | WP_001211258.1 | CtsR family transcriptional regulator | - |
| FD735_RS09455 (FD735_09455) | - | 1833492..1833812 (-) | 321 | WP_125391513.1 | hypothetical protein | - |
| FD735_RS09460 (FD735_09460) | - | 1833802..1834263 (-) | 462 | WP_125391512.1 | Panacea domain-containing protein | - |
| FD735_RS09975 | - | 1834405..1834755 (-) | 351 | WP_255296286.1 | hypothetical protein | - |
| FD735_RS09470 (FD735_09470) | - | 1834771..1835061 (-) | 291 | WP_139659054.1 | hypothetical protein | - |
| FD735_RS09475 (FD735_09475) | - | 1835111..1835323 (-) | 213 | WP_033630508.1 | hypothetical protein | - |
| FD735_RS09480 (FD735_09480) | - | 1835592..1835933 (-) | 342 | WP_139659119.1 | HNH endonuclease | - |
| FD735_RS09485 (FD735_09485) | - | 1836115..1836762 (-) | 648 | WP_139659055.1 | hypothetical protein | - |
| FD735_RS09490 (FD735_09490) | - | 1837282..1838736 (-) | 1455 | WP_125391509.1 | virulence-associated E family protein | - |
| FD735_RS09495 (FD735_09495) | - | 1838729..1839244 (-) | 516 | WP_125391508.1 | hypothetical protein | - |
| FD735_RS09500 (FD735_09500) | - | 1839241..1839504 (-) | 264 | WP_125391507.1 | hypothetical protein | - |
| FD735_RS09980 (FD735_09505) | - | 1839506..1839715 (-) | 210 | WP_125391506.1 | hypothetical protein | - |
| FD735_RS09985 (FD735_09510) | - | 1839717..1839920 (-) | 204 | WP_084930585.1 | hypothetical protein | - |
| FD735_RS09835 | - | 1840129..1840278 (-) | 150 | WP_162837410.1 | hypothetical protein | - |
| FD735_RS09515 (FD735_09515) | - | 1840281..1840709 (-) | 429 | WP_139659056.1 | hypothetical protein | - |
| FD735_RS09520 (FD735_09520) | - | 1840829..1841083 (-) | 255 | WP_125391504.1 | hypothetical protein | - |
| FD735_RS09525 (FD735_09525) | - | 1841338..1841523 (-) | 186 | WP_000909283.1 | hypothetical protein | - |
| FD735_RS09530 (FD735_09530) | - | 1841679..1842263 (+) | 585 | WP_139659057.1 | helix-turn-helix transcriptional regulator | - |
| FD735_RS09535 (FD735_09535) | - | 1842298..1842567 (+) | 270 | WP_004261908.1 | DUF4177 domain-containing protein | - |
| FD735_RS09540 (FD735_09540) | - | 1842828..1843292 (+) | 465 | WP_049510243.1 | hypothetical protein | - |
| FD735_RS09545 (FD735_09545) | - | 1843285..1844073 (+) | 789 | WP_049510244.1 | DUF1828 domain-containing protein | - |
| FD735_RS09555 (FD735_09555) | - | 1844479..1845645 (+) | 1167 | WP_139659058.1 | site-specific integrase | - |
| FD735_RS09560 (FD735_09560) | - | 1845965..1848832 (-) | 2868 | WP_139659059.1 | Spy0128 family protein | - |
| FD735_RS09565 (FD735_09565) | - | 1849038..1849766 (-) | 729 | WP_139659060.1 | ABC transporter ATP-binding protein | - |
| FD735_RS09570 (FD735_09570) | - | 1849766..1850773 (-) | 1008 | WP_139659061.1 | ABC transporter substrate-binding protein | - |
| FD735_RS09575 (FD735_09575) | - | 1850811..1851569 (-) | 759 | WP_139659062.1 | ABC transporter permease | - |
| FD735_RS09580 (FD735_09580) | - | 1851532..1851822 (-) | 291 | WP_139659063.1 | thiamine-binding protein | - |
| FD735_RS09585 (FD735_09585) | polA | 1852101..1854734 (-) | 2634 | WP_139659064.1 | DNA polymerase I | - |
| FD735_RS09590 (FD735_09590) | - | 1854865..1857894 (-) | 3030 | WP_139659065.1 | SIALI-17 repeat-containing surface protein | - |
| FD735_RS09595 (FD735_09595) | - | 1858010..1859131 (-) | 1122 | WP_139659066.1 | CHAP domain-containing protein | - |
| FD735_RS09600 (FD735_09600) | - | 1859231..1859497 (-) | 267 | WP_001278165.1 | Veg family protein | - |
| FD735_RS09605 (FD735_09605) | dnaB | 1859499..1860851 (-) | 1353 | WP_000852476.1 | replicative DNA helicase | - |
| FD735_RS09610 (FD735_09610) | rplI | 1860895..1861347 (-) | 453 | WP_000864208.1 | 50S ribosomal protein L9 | - |
| FD735_RS09615 (FD735_09615) | - | 1861344..1863317 (-) | 1974 | WP_139659067.1 | DHH family phosphoesterase | - |
| FD735_RS09620 (FD735_09620) | - | 1863474..1864652 (-) | 1179 | WP_139659120.1 | acetyl-CoA C-acetyltransferase | - |
| FD735_RS09625 (FD735_09625) | raiA | 1864734..1865282 (-) | 549 | WP_000599111.1 | ribosome hibernation-promoting factor, HPF/YfiA family | - |
| FD735_RS09630 (FD735_09630) | comFC/cflB | 1865362..1866024 (-) | 663 | WP_139659068.1 | ComF family protein | Machinery gene |
| FD735_RS09635 (FD735_09635) | comFA/cflA | 1866021..1867319 (-) | 1299 | WP_139659069.1 | DEAD/DEAH box helicase | Machinery gene |
| FD735_RS09640 (FD735_09640) | - | 1867376..1868011 (+) | 636 | WP_139659070.1 | YigZ family protein | - |
| FD735_RS09645 (FD735_09645) | - | 1868026..1868469 (+) | 444 | WP_139659071.1 | PH domain-containing protein | - |
| FD735_RS09650 (FD735_09650) | cysK | 1868566..1869492 (+) | 927 | WP_139659072.1 | cysteine synthase A | - |
| FD735_RS09655 (FD735_09655) | tsf | 1869596..1870636 (-) | 1041 | WP_139659073.1 | translation elongation factor Ts | - |
| FD735_RS09660 (FD735_09660) | rpsB | 1870715..1871494 (-) | 780 | WP_000268475.1 | 30S ribosomal protein S2 | - |
| FD735_RS09665 (FD735_09665) | pcsB | 1871717..1872928 (-) | 1212 | WP_139659074.1 | peptidoglycan hydrolase PcsB | - |
| FD735_RS09670 (FD735_09670) | mreD | 1873022..1873516 (-) | 495 | WP_049477904.1 | rod shape-determining protein MreD | - |
| FD735_RS09675 (FD735_09675) | mreC | 1873519..1874334 (-) | 816 | WP_139659075.1 | rod shape-determining protein MreC | - |
| FD735_RS09680 (FD735_09680) | - | 1874395..1875189 (-) | 795 | WP_139659076.1 | energy-coupling factor transporter transmembrane protein EcfT | - |
| FD735_RS09685 (FD735_09685) | - | 1875182..1876021 (-) | 840 | WP_084944240.1 | energy-coupling factor transporter ATPase | - |
| FD735_RS09690 (FD735_09690) | - | 1876006..1876833 (-) | 828 | WP_139659077.1 | energy-coupling factor ABC transporter ATP-binding protein | - |
| FD735_RS09695 (FD735_09695) | pgsA | 1876830..1877375 (-) | 546 | WP_139659078.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| FD735_RS09700 (FD735_09700) | rodZ | 1877386..1878207 (-) | 822 | WP_176553070.1 | cytoskeleton protein RodZ | - |
| FD735_RS09705 (FD735_09705) | - | 1878243..1879526 (-) | 1284 | WP_125391774.1 | EF-P 5-aminopentanol modification-associated protein YfmH | - |
| FD735_RS09710 (FD735_09710) | - | 1879523..1880773 (-) | 1251 | WP_139659080.1 | EF-P 5-aminopentanol modification-associated protein YfmF | - |
| FD735_RS09715 (FD735_09715) | yaaA | 1880934..1881302 (+) | 369 | WP_139659081.1 | S4 domain-containing protein YaaA | - |
| FD735_RS09720 (FD735_09720) | recF | 1881305..1882396 (+) | 1092 | WP_139659082.1 | DNA replication/repair protein RecF | - |
| FD735_RS09725 (FD735_09725) | guaB | 1882455..1883933 (-) | 1479 | WP_071851777.1 | IMP dehydrogenase | - |
Sequence
Protein
Download Length: 220 a.a. Molecular weight: 25206.10 Da Isoelectric Point: 5.8735
>NTDB_id=362676 FD735_RS09630 WP_139659068.1 1865362..1866024(-) (comFC/cflB) [Streptococcus sp. 1643]
MNCLLCGQTIKSDLMFCHLLLFKNENNYLCSDCESTFEKIGEDYCPNCMKTGLSTVCQDCKFWCKEEILVNHNAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFAPVLANELKKYGDYQFVVIPLSPERLLERGFNQVEGLVEAAGFSFQDLLGKREETASSS
KNRSERLATEIPFFIKTEAPLPKKILVIDDIYTTGATVNRVKRLFEEAGALDVKTFSLVR
MNCLLCGQTIKSDLMFCHLLLFKNENNYLCSDCESTFEKIGEDYCPNCMKTGLSTVCQDCKFWCKEEILVNHNAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFAPVLANELKKYGDYQFVVIPLSPERLLERGFNQVEGLVEAAGFSFQDLLGKREETASSS
KNRSERLATEIPFFIKTEAPLPKKILVIDDIYTTGATVNRVKRLFEEAGALDVKTFSLVR
Nucleotide
Download Length: 663 bp
>NTDB_id=362676 FD735_RS09630 WP_139659068.1 1865362..1866024(-) (comFC/cflB) [Streptococcus sp. 1643]
ATGAACTGTTTATTATGTGGACAGACAATAAAGAGTGACCTGATGTTTTGTCACCTCTTGCTGTTTAAGAATGAGAACAA
CTATCTTTGTTCAGATTGTGAGTCTACTTTTGAGAAAATTGGTGAGGACTATTGCCCGAACTGTATGAAAACAGGGCTGT
CAACCGTGTGTCAAGACTGTAAATTTTGGTGTAAAGAAGAGATTCTAGTCAATCATAATGCAATCTTCACCTATAATCAA
GCTATGAAAGACTTCTTTAGTCGATATAAGTTTGATGGGGATTTTCTACTTAGAAAGGTTTTTGCTCCTGTTCTTGCTAA
TGAATTGAAAAAGTATGGAGACTATCAATTTGTTGTTATTCCCCTAAGTCCTGAAAGATTGCTTGAGAGGGGATTTAACC
AGGTTGAAGGTTTGGTTGAGGCAGCAGGTTTTTCTTTTCAAGATTTACTAGGGAAAAGAGAAGAGACGGCTAGTTCTTCT
AAGAATCGCTCGGAACGATTAGCTACCGAAATTCCATTTTTTATAAAAACTGAAGCCCCTCTTCCTAAGAAAATTTTGGT
TATTGATGACATCTATACAACAGGTGCGACTGTCAATCGTGTGAAGCGTCTTTTTGAAGAAGCAGGAGCTTTGGATGTTA
AAACTTTTTCCCTTGTAAGATGA
ATGAACTGTTTATTATGTGGACAGACAATAAAGAGTGACCTGATGTTTTGTCACCTCTTGCTGTTTAAGAATGAGAACAA
CTATCTTTGTTCAGATTGTGAGTCTACTTTTGAGAAAATTGGTGAGGACTATTGCCCGAACTGTATGAAAACAGGGCTGT
CAACCGTGTGTCAAGACTGTAAATTTTGGTGTAAAGAAGAGATTCTAGTCAATCATAATGCAATCTTCACCTATAATCAA
GCTATGAAAGACTTCTTTAGTCGATATAAGTTTGATGGGGATTTTCTACTTAGAAAGGTTTTTGCTCCTGTTCTTGCTAA
TGAATTGAAAAAGTATGGAGACTATCAATTTGTTGTTATTCCCCTAAGTCCTGAAAGATTGCTTGAGAGGGGATTTAACC
AGGTTGAAGGTTTGGTTGAGGCAGCAGGTTTTTCTTTTCAAGATTTACTAGGGAAAAGAGAAGAGACGGCTAGTTCTTCT
AAGAATCGCTCGGAACGATTAGCTACCGAAATTCCATTTTTTATAAAAACTGAAGCCCCTCTTCCTAAGAAAATTTTGGT
TATTGATGACATCTATACAACAGGTGCGACTGTCAATCGTGTGAAGCGTCTTTTTGAAGAAGCAGGAGCTTTGGATGTTA
AAACTTTTTCCCTTGTAAGATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comFC/cflB | Streptococcus mitis SK321 |
78.182 |
100 |
0.782 |
| comFC/cflB | Streptococcus mitis NCTC 12261 |
76.364 |
100 |
0.764 |
| comFC/cflB | Streptococcus pneumoniae D39 |
75.909 |
100 |
0.759 |
| comFC/cflB | Streptococcus pneumoniae TIGR4 |
75.909 |
100 |
0.759 |
| comFC/cflB | Streptococcus pneumoniae R6 |
75.909 |
100 |
0.759 |
| comFC/cflB | Streptococcus pneumoniae Rx1 |
75.909 |
100 |
0.759 |
| comFC | Bacillus subtilis subsp. subtilis str. 168 |
35.683 |
100 |
0.368 |