Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   FD735_RS00215 Genome accession   NZ_CP040231
Coordinates   36695..38044 (+) Length   449 a.a.
NCBI ID   WP_139658204.1    Uniprot ID   A0A5B7Y396
Organism   Streptococcus sp. 1643     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 31695..43044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS00180 (FD735_00180) plsX 31841..32833 (+) 993 WP_139658202.1 phosphate acyltransferase PlsX -
  FD735_RS00185 (FD735_00185) - 32839..33075 (+) 237 WP_000136435.1 acyl carrier protein -
  FD735_RS00190 (FD735_00190) - 33514..33702 (+) 189 WP_049501355.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  FD735_RS00195 (FD735_00195) - 33720..33887 (+) 168 WP_000415691.1 bacteriocin -
  FD735_RS00200 (FD735_00200) - 33897..34085 (+) 189 WP_139658203.1 hypothetical protein -
  FD735_RS00205 (FD735_00205) - 34110..34319 (+) 210 WP_125414669.1 bacteriocin immunity protein -
  FD735_RS00210 (FD735_00210) comA 34529..36682 (+) 2154 WP_125414668.1 peptide cleavage/export ABC transporter ComA Regulator
  FD735_RS00215 (FD735_00215) comB 36695..38044 (+) 1350 WP_139658204.1 competence pheromone export protein ComB Regulator
  FD735_RS00220 (FD735_00220) purC 38213..38920 (+) 708 WP_139658205.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  FD735_RS09860 - 39000..39065 (+) 66 Protein_37 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  FD735_RS00230 (FD735_00230) - 39133..42858 (+) 3726 WP_139658206.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49990.98 Da        Isoelectric Point: 5.2480

>NTDB_id=362611 FD735_RS00215 WP_139658204.1 36695..38044(+) (comB) [Streptococcus sp. 1643]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQLIVANYLEENKL
VKQGELLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQANSLRSNVSQQN
ASISSQNAAASQSQTEIGNLISQTQDKIRDYKTAKSAIETGDQLDSQNPAYSFYQTYKNQGEEDPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAHATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETHLTSEQAEKLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=362611 FD735_RS00215 WP_139658204.1 36695..38044(+) (comB) [Streptococcus sp. 1643]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGCTCGTGTTTTTACTGGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTGTCTACCAGAGCGACTGTTG
AACCTAGTCGGATCATTGCTAATATCCAGTCGACTAGCAATCAACTCATCGTGGCCAATTATCTAGAAGAAAACAAACTA
GTCAAGCAGGGGGAACTCCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTTGAGGCATATGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCAG
ATAAGTTTGGTTACCAGGAGATGTTTCGAGATTATCTCAGCCAAGCGAATAGTCTAAGAAGTAATGTTTCTCAACAAAAT
GCTAGCATATCTTCTCAAAATGCGGCAGCAAGTCAGAGCCAGACCGAGATTGGCAATCTTATCAGTCAAACACAGGATAA
AATTCGAGATTATAAAACAGCTAAGTCGGCGATTGAAACAGGGGATCAACTGGATAGTCAGAATCCAGCCTACTCTTTTT
ATCAGACCTATAAAAATCAAGGTGAAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCGCAAGTGGATGCACAAATTGCT
CAGCTAGAGTCCAGTCTAGCTACGTATCGTGTACAGTATGCGGGTTCTGGAGCTCAACAGGCTCATGCAACGGGACTGGA
TAGTCAACTGGAATCGCTCAAATCTCAGCACTTAGTCAAAGTCGGTCAGGAATTAACTCTTTTGGATCAGAAAATTTTGG
AGGCGGAATCGGGTAAGAAGGTACAGGGAGGTCTCCTAGATAAAGGGAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTCAATCCTGAGACTAGTGAATCTACGATGGTCGCAGAAGGAACCCTGCTAGCCCAACTCTACCCATCCTTGGAAAAAGA
AGGGAAAACCAAACTCACAGCTTATCTCAGTTCAAAAGATGTTGCTAGAGTCAAGATTGGGGACTCTGTTCGTTATACTA
CGACTAATGATGCGAAGAATCAAATTTTCCTGGATTCTACGATTACAAGTATCGATGCGACAGCTACAAAGACTGAAAAA
GGGAATTTCTTTAAAATTGAGGCGGAGACCCATCTGACTTCTGAGCAGGCTGAAAAACTTCGCTATGGTTTAGAAGGCCG
CCTGCAGATGATTACGGGAAAGAAAAGCTATCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5B7Y396

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

84.152

99.777

0.84
  comB Streptococcus pneumoniae Rx1

82.812

99.777

0.826
  comB Streptococcus pneumoniae D39

82.812

99.777

0.826
  comB Streptococcus pneumoniae R6

82.812

99.777

0.826
  comB Streptococcus pneumoniae TIGR4

82.366

99.777

0.822
  comB Streptococcus mitis NCTC 12261

82.143

99.777

0.82
  comB Streptococcus gordonii str. Challis substr. CH1

55.31

100

0.557

Multiple sequence alignment