Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   FAH67_RS09835 Genome accession   NZ_CP039886
Coordinates   1921825..1923015 (+) Length   396 a.a.
NCBI ID   WP_003679496.1    Uniprot ID   C0EKN5
Organism   Neisseria flavescens strain ATCC 13120     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1916825..1928015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FAH67_RS09820 (FAH67_09820) - 1917605..1918198 (+) 594 WP_003679492.1 DUF4390 domain-containing protein -
  FAH67_RS09825 (FAH67_09825) - 1918202..1920328 (+) 2127 WP_115287659.1 PAS domain-containing sensor histidine kinase -
  FAH67_RS09830 (FAH67_09830) - 1920315..1921589 (+) 1275 WP_003679494.1 sigma-54 dependent transcriptional regulator -
  FAH67_RS09835 (FAH67_09835) dprA 1921825..1923015 (+) 1191 WP_003679496.1 DNA-processing protein DprA Machinery gene
  FAH67_RS09840 (FAH67_09840) - 1923040..1923201 (+) 162 Protein_1881 DUF494 family protein -
  FAH67_RS11915 (FAH67_09845) - 1923225..1923707 (-) 483 WP_112890822.1 transposase -
  FAH67_RS11920 (FAH67_09850) - 1923725..1923988 (-) 264 WP_112890679.1 transposase -
  FAH67_RS09855 (FAH67_09855) - 1924020..1924316 (+) 297 Protein_1884 DUF494 family protein -
  FAH67_RS09860 (FAH67_09860) topA 1924396..1926702 (+) 2307 WP_003679500.1 type I DNA topoisomerase -
  FAH67_RS09865 (FAH67_09865) - 1926774..1927469 (-) 696 WP_003679502.1 hypothetical protein -

Sequence

Protein


Download         Length: 396 a.a.        Molecular weight: 42801.78 Da        Isoelectric Point: 5.8852

>NTDB_id=360915 FAH67_RS09835 WP_003679496.1 1921825..1923015(+) (dprA) [Neisseria flavescens strain ATCC 13120]
MTENERFAWLQLAFTPYIGAESFLVLLQQFGNAQAALNAPADRIAALVRHKQAAESWRNADKRALAQQSAEAALQWEMQD
GCRLLLLQDDDFPEMLTQGITAPPVLFLRGNAELLHTPSAAIVGSRHATPQAMRIAKDFGRALGEKGIPVVSGMASGIDT
AAHQGALQADGGTIAVWGTGIDRIYPPSNKNLAYEIAERGLIVSEFPLDTRPFAGNFPRRNRLIAALSQLTLVVEAALES
GSLITAKLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILHECPQLLQNTPVPSYSINKTVKPKNNQTERL
QPKTRADEPQRPSENLPAAPSTSALLEAMGYDPIHPDILAQQTNTAAADVYAQLLEYELDGIVAALPGGRYQRVKA

Nucleotide


Download         Length: 1191 bp        

>NTDB_id=360915 FAH67_RS09835 WP_003679496.1 1921825..1923015(+) (dprA) [Neisseria flavescens strain ATCC 13120]
ATGACGGAAAACGAGCGTTTTGCTTGGTTGCAACTGGCATTTACGCCTTATATCGGCGCAGAAAGTTTTTTGGTGCTGTT
GCAGCAATTCGGTAATGCACAAGCTGCCTTGAATGCGCCGGCAGATAGAATTGCCGCGTTGGTGCGCCATAAACAGGCAG
CCGAGTCGTGGCGCAATGCAGATAAACGGGCTTTGGCGCAGCAGTCTGCCGAAGCCGCTTTACAATGGGAAATGCAGGAC
GGTTGCCGTTTGTTGCTGCTGCAAGATGATGATTTCCCCGAAATGCTGACACAAGGCATTACCGCGCCGCCGGTCTTGTT
TTTACGCGGCAATGCAGAGCTGCTGCACACACCTTCTGCCGCGATTGTCGGCAGCCGCCATGCCACGCCGCAGGCAATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGAAAAGGGCATTCCCGTCGTATCGGGTATGGCTTCGGGTATCGATACC
GCTGCACATCAAGGTGCATTGCAGGCAGATGGCGGTACCATTGCCGTCTGGGGAACCGGTATAGACCGCATTTATCCGCC
ATCCAATAAAAACCTTGCTTATGAAATTGCCGAAAGAGGATTGATTGTCAGCGAGTTTCCTTTGGATACGCGGCCTTTTG
CGGGCAACTTTCCGCGCCGCAACCGTTTGATTGCCGCATTATCGCAGCTGACATTGGTGGTCGAGGCGGCATTGGAATCC
GGCTCATTGATTACCGCCAAGCTGGCGGCGGAGATGGGACGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAGCTGATTAAAGACGGGGCAAAACTGGTGGAATGTTTGGACGATATTCTCCATGAGTGTCCGC
AGCTATTGCAAAATACGCCTGTTCCATCATATTCTATAAATAAGACGGTCAAACCGAAAAACAATCAAACCGAACGTCTG
CAACCAAAAACAAGAGCGGATGAACCGCAAAGGCCGTCTGAAAACCTACCTGCCGCCCCATCAACAAGCGCTTTATTGGA
AGCAATGGGTTACGACCCGATACACCCCGATATTTTGGCGCAACAAACCAATACGGCAGCGGCAGACGTGTACGCACAGC
TTTTGGAATACGAACTTGACGGTATCGTCGCCGCCTTGCCGGGCGGCCGTTATCAGCGTGTCAAAGCATAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(79-283)

DprA winged helix domain (DprA_WH)

(332-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0EKN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Neisseria meningitidis strain C311

77.273

100

0.773
  dprA Neisseria meningitidis MC58

77.273

100

0.773
  dprA Neisseria gonorrhoeae MS11

76.633

100

0.77
  dprA Neisseria gonorrhoeae strain FA1090

76.131

100

0.765
  dprA Vibrio cholerae strain A1552

38.071

99.495

0.379
  dprA Glaesserella parasuis strain SC1401

43.323

85.101

0.369
  dprA Vibrio campbellii strain DS40M4

37.209

97.727

0.364

Multiple sequence alignment