Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I33_RS19560 Genome accession   NC_017195
Coordinates   3952089..3953291 (-) Length   400 a.a.
NCBI ID   WP_014478539.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis str. RO-NN-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3947089..3958291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I33_RS19545 (I33_4203) rocE 3947322..3948725 (-) 1404 WP_014478536.1 amino acid permease -
  I33_RS19550 (I33_4204) rocD 3948948..3950153 (-) 1206 WP_014478537.1 ornithine aminotransferase -
  I33_RS19555 (I33_4205) rocR 3950394..3951776 (+) 1383 WP_014478538.1 arginine utilization regulatory protein RocR -
  I33_RS21125 - 3951758..3951909 (-) 152 Protein_3941 ATP-binding protein -
  I33_RS21130 - 3951937..3952068 (-) 132 Protein_3942 hypothetical protein -
  I33_RS19560 (I33_4206) htrA 3952089..3953291 (-) 1203 WP_014478539.1 serine protease HtrC Regulator
  I33_RS19565 (I33_4207) vicX 3953373..3954167 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  I33_RS19570 (I33_4208) walI 3954189..3955031 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  I33_RS19575 (I33_4209) walH 3955018..3956385 (-) 1368 WP_014478540.1 WalRK two-component regulatory system regulator WalH -
  I33_RS19580 (I33_4210) walK 3956375..3958210 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42728.48 Da        Isoelectric Point: 5.3354

>NTDB_id=36053 I33_RS19560 WP_014478539.1 3952089..3953291(-) (htrA) [Bacillus subtilis subsp. subtilis str. RO-NN-1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLEKYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=36053 I33_RS19560 WP_014478539.1 3952089..3953291(-) (htrA) [Bacillus subtilis subsp. subtilis str. RO-NN-1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTAAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATTCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAAATACGGAAAGGTCAAAC
GCCCGTTCCTTGGGATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTTACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(200-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.264

96.5

0.417
  htrA Streptococcus pneumoniae TIGR4

45.455

82.5

0.375
  htrA Streptococcus pneumoniae D39

45.455

82.5

0.375
  htrA Streptococcus pneumoniae Rx1

45.455

82.5

0.375
  htrA Streptococcus pneumoniae R6

45.455

82.5

0.375

Multiple sequence alignment