Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FA707_RS09955 Genome accession   NZ_CP039712
Coordinates   2104451..2105710 (+) Length   419 a.a.
NCBI ID   WP_136954055.1    Uniprot ID   A0A4D7CUZ5
Organism   Vagococcus zengguangii strain MN-17     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2099451..2110710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FA707_RS09935 (FA707_09935) sdaAA 2100680..2101555 (-) 876 WP_136954051.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  FA707_RS09940 (FA707_09940) sdaAB 2101569..2102276 (-) 708 WP_136954052.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  FA707_RS09945 (FA707_09945) - 2102522..2103406 (-) 885 WP_136954053.1 AbaSI family restriction endonuclease -
  FA707_RS09950 (FA707_09950) rlmH 2103431..2103910 (-) 480 WP_136954054.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FA707_RS09955 (FA707_09955) htrA 2104451..2105710 (+) 1260 WP_136954055.1 trypsin-like peptidase domain-containing protein Regulator
  FA707_RS09960 (FA707_09960) - 2105758..2106924 (-) 1167 WP_136954056.1 cation:proton antiporter -
  FA707_RS09965 (FA707_09965) - 2107098..2108315 (-) 1218 WP_136954057.1 GNAT family N-acetyltransferase -
  FA707_RS09970 (FA707_09970) - 2108349..2108978 (-) 630 WP_136954058.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FA707_RS09975 (FA707_09975) - 2109121..2109855 (+) 735 WP_136954234.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  FA707_RS09980 (FA707_09980) - 2109845..2110150 (+) 306 WP_136954059.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 44003.58 Da        Isoelectric Point: 4.3920

>NTDB_id=360310 FA707_RS09955 WP_136954055.1 2104451..2105710(+) (htrA) [Vagococcus zengguangii strain MN-17]
MEQEHQEFNNQKKSSLLKRFGVSLAGGILGGGLVFGGAQLVTNDSTNSVVENKGNTQVSTINYDVKSDTTKAVSKVQDAV
VSVINLQKQQTSNDPFGGLFGGGSTQSSDNDKDDLQTTSEGSGVIYRKDGDNAYIVTNNHVVSGSDALEILFSDGTTVKG
ELVGRDSYTDLAVIKINSKNVKTVAEFGDSDAIKVGEPAIAIGSPLGTEYASSVTQGIISAKNRSIQNTNDDNEPVNINA
IQTDAAINPGNSGGALVNAAGQVIGINSVKIASSNSGVSAEGMGFAIPSNDVVNIINQLEKDGKVTRPALGVTMYDLANI
SSQQRSQILNLTDEVTAGVAVITVQNATPAEKAGLQQYDVIVDIDGEAIESASDLQSILYNKKVGDKIKVTYYRGKDKKT
TTVELSIDQSALQQNNSDQ

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=360310 FA707_RS09955 WP_136954055.1 2104451..2105710(+) (htrA) [Vagococcus zengguangii strain MN-17]
ATGGAACAAGAACATCAAGAATTTAATAATCAGAAAAAATCTAGTTTGTTAAAACGATTCGGCGTAAGTTTAGCCGGTGG
TATTTTAGGTGGTGGTCTAGTTTTTGGTGGAGCGCAATTAGTCACTAACGATTCCACTAACTCTGTTGTTGAAAACAAAG
GCAACACGCAAGTAAGTACAATCAACTATGATGTTAAAAGCGATACAACAAAAGCCGTCTCTAAAGTACAAGATGCAGTT
GTTTCAGTGATTAATTTACAAAAGCAACAAACTAGCAACGATCCATTTGGGGGTCTATTCGGTGGCGGTAGCACACAATC
TTCAGATAATGACAAAGATGATTTACAAACGACTAGTGAAGGTAGCGGCGTTATTTACCGCAAAGATGGGGATAATGCCT
ATATCGTCACCAATAACCACGTGGTTTCAGGTTCGGATGCATTAGAGATTTTATTTAGCGATGGTACGACTGTCAAAGGT
GAACTAGTTGGACGCGACTCTTACACTGACTTAGCTGTCATCAAAATCAATAGTAAAAACGTAAAAACAGTTGCTGAATT
TGGTGACTCTGATGCGATTAAAGTCGGTGAACCTGCGATTGCGATTGGCTCTCCACTAGGTACTGAGTATGCAAGTTCCG
TTACCCAAGGAATTATTTCTGCTAAAAACCGCAGTATTCAAAACACCAATGACGACAATGAGCCTGTTAACATTAACGCA
ATTCAAACAGATGCTGCTATCAACCCAGGTAACTCAGGTGGGGCTTTAGTTAATGCTGCTGGCCAAGTTATCGGTATTAA
TTCTGTTAAAATTGCCTCATCAAATTCCGGTGTTTCCGCAGAAGGAATGGGCTTTGCTATTCCAAGTAACGATGTGGTGA
ATATCATTAACCAATTAGAAAAAGACGGAAAAGTAACACGTCCTGCACTTGGTGTAACCATGTACGATTTAGCGAATATT
AGCTCACAACAACGTAGCCAAATCTTGAATTTAACTGATGAGGTAACTGCTGGTGTGGCGGTTATTACGGTTCAAAATGC
AACACCTGCTGAAAAAGCTGGTTTACAGCAATACGATGTGATTGTCGATATCGACGGTGAAGCCATTGAATCAGCTAGTG
ACTTACAATCTATTCTTTACAACAAAAAAGTTGGTGATAAGATTAAGGTGACTTACTACCGTGGCAAAGATAAGAAAACA
ACTACTGTTGAATTAAGCATCGATCAATCAGCGCTACAACAAAATAATAGCGATCAATAG

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(13-406)

PDZ domain (PDZ_2)

(308-405)

Trypsin-like peptidase domain (Trypsin_2)

(121-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4D7CUZ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

54.208

96.42

0.523
  htrA Streptococcus mitis NCTC 12261

50.249

95.943

0.482
  htrA Streptococcus pneumoniae Rx1

49.628

96.181

0.477
  htrA Streptococcus pneumoniae D39

49.628

96.181

0.477
  htrA Streptococcus pneumoniae R6

49.628

96.181

0.477
  htrA Streptococcus pneumoniae TIGR4

49.628

96.181

0.477
  htrA Streptococcus gordonii str. Challis substr. CH1

49.872

93.317

0.465

Multiple sequence alignment