Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   E8M06_RS07580 Genome accession   NZ_CP039462
Coordinates   1537237..1537941 (-) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain WUSS351     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1532237..1542941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M06_RS07565 (E8M06_07575) vga(F) 1533442..1534827 (-) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -
  E8M06_RS07570 (E8M06_07580) vicX 1535085..1535888 (-) 804 WP_024399908.1 MBL fold metallo-hydrolase Regulator
  E8M06_RS07575 (E8M06_07585) micB 1535895..1537244 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  E8M06_RS07580 (E8M06_07590) micA 1537237..1537941 (-) 705 WP_002935840.1 response regulator YycF Regulator
  E8M06_RS07585 (E8M06_07595) - 1538135..1538896 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  E8M06_RS07590 (E8M06_07600) - 1538907..1539746 (+) 840 WP_136581444.1 transporter substrate-binding domain-containing protein -
  E8M06_RS07595 (E8M06_07605) - 1539761..1540459 (+) 699 WP_004298848.1 amino acid ABC transporter permease -
  E8M06_RS07600 (E8M06_07610) - 1540474..1541133 (+) 660 WP_024378367.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=358855 E8M06_RS07580 WP_002935840.1 1537237..1537941(-) (micA) [Streptococcus suis strain WUSS351]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=358855 E8M06_RS07580 WP_002935840.1 1537237..1537941(-) (micA) [Streptococcus suis strain WUSS351]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGCCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTAGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment